Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770601688> ?p ?o ?g. }
- W2770601688 abstract "Using a variant of Hamilton-replica-exchange, we study for wild type and Iowa mutant Aβ40 the conversion between fibrils with antiparallel β-sheets and such with parallel β-sheets. We show that wild type and mutant form distinct salt bridges that in turn stabilize different fibril organizations. The conversion between the two fibril forms leads to the release of small aggregates that in the Iowa mutant may shift the equilibrium from fibrils to more toxic oligomers." @default.
- W2770601688 created "2017-12-04" @default.
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- W2770601688 date "2018-01-25" @default.
- W2770601688 modified "2023-09-24" @default.
- W2770601688 title "Conversion between parallel and antiparallel β-sheets in wild-type and Iowa mutant Aβ40 fibrils" @default.
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- W2770601688 doi "https://doi.org/10.1063/1.5016166" @default.
- W2770601688 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5785298" @default.
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