FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770610507> ?p ?o ?g. }

• W2770610507 endingPage "e018758" @default.
• W2770610507 startingPage "e018758" @default.
• W2770610507 abstract "Women at high inherited risk of ovarian cancer are advised to undergo risk-reducing bilateral salpingo-oophorectomy (RRBSO) at age 40-45 years or when their families are complete. Most women are premenopausal at this age, so RRBSO will induce surgical menopause. Despite the clear benefits of RRBSO for cancer risk reduction, much less is known about the impact on non-cancer outcomes that contribute to health and well-being and inform surveillance and management strategies.This will be a multicentre, prospective cohort study of 105 premenopausal high-risk women undergoing RRBSO and an age-matched comparison group of 105 premenopausal women not planning oophorectomy or pregnancy in the next 2 years. The aim of this study is to measure the impact of RRBSO on sexual function (primary outcome) at 24 months in high-risk premenopausal women compared with the comparison group. Secondary outcomes include menopausal symptoms and menopause-related quality of life, mood, sleep quality, markers of cardiovascular disease and pre-diabetes, bone density and markers of bone turnover, and the impact of hormone replacement therapy use on these outcomes. Data analysis methods will include logistic and linear regression using general estimating equations accounting for the repeated outcome measurements within each participant.The study has been approved by institutional ethics committees at each participating centre. Findings will be disseminated through peer-reviewed publications and conference presentations, and national and international networks of centres managing high-risk women, and will inform national and international clinical guidelines.The pre-results protocol for this trial is registered with the Australian New Zealand Clinical Trials Registry (anzctr.org.au; registration no: ACTRN12615000082505)." @default.
• W2770610507 created "2017-12-04" @default.
• W2770610507 creator A5014432451 @default.
• W2770610507 creator A5014440215 @default.
• W2770610507 creator A5016560016 @default.
• W2770610507 creator A5031492399 @default.
• W2770610507 creator A5032931204 @default.
• W2770610507 creator A5050220299 @default.
• W2770610507 date "2017-11-01" @default.
• W2770610507 modified "2023-10-14" @default.
• W2770610507 title "What Happens After Menopause? (WHAM): protocol for a prospective, multicentre, age-matched cohort trial of risk-reducing bilateral salpingo-oophorectomy in high-risk premenopausal women" @default.
• W2770610507 cites W1600720583 @default.
• W2770610507 cites W1960696489 @default.
• W2770610507 cites W1964663917 @default.
• W2770610507 cites W1968585700 @default.
• W2770610507 cites W1973362112 @default.
• W2770610507 cites W1974403799 @default.
• W2770610507 cites W1976566530 @default.
• W2770610507 cites W1977022270 @default.
• W2770610507 cites W1977975426 @default.
• W2770610507 cites W1978322339 @default.
• W2770610507 cites W2000488225 @default.
• W2770610507 cites W2002392345 @default.
• W2770610507 cites W2004405160 @default.
• W2770610507 cites W2013526042 @default.
• W2770610507 cites W2029253341 @default.
• W2770610507 cites W2034572972 @default.
• W2770610507 cites W2035950836 @default.
• W2770610507 cites W2043705607 @default.
• W2770610507 cites W2070850090 @default.
• W2770610507 cites W2083026155 @default.
• W2770610507 cites W2083737455 @default.
• W2770610507 cites W2086063287 @default.
• W2770610507 cites W2089198100 @default.
• W2770610507 cites W2092050711 @default.
• W2770610507 cites W2093274439 @default.
• W2770610507 cites W2093288889 @default.
• W2770610507 cites W2098247759 @default.
• W2770610507 cites W2112997260 @default.
• W2770610507 cites W2113002312 @default.
• W2770610507 cites W2120385927 @default.
• W2770610507 cites W2123232353 @default.
• W2770610507 cites W2125921569 @default.
• W2770610507 cites W2135525536 @default.
• W2770610507 cites W2135650147 @default.
• W2770610507 cites W2136504378 @default.
• W2770610507 cites W2142535080 @default.
• W2770610507 cites W2148141599 @default.
• W2770610507 cites W2151487996 @default.
• W2770610507 cites W2159899668 @default.
• W2770610507 cites W2160795987 @default.
• W2770610507 cites W2174260157 @default.
• W2770610507 cites W2183506486 @default.
• W2770610507 cites W2269179103 @default.
• W2770610507 cites W2410337299 @default.
• W2770610507 cites W2466624553 @default.
• W2770610507 cites W2477763233 @default.
• W2770610507 cites W2486332150 @default.
• W2770610507 cites W2510812305 @default.
• W2770610507 cites W2524870530 @default.
• W2770610507 cites W2586145437 @default.
• W2770610507 cites W2586772518 @default.
• W2770610507 cites W2627871710 @default.
• W2770610507 cites W2733102233 @default.
• W2770610507 cites W4230202275 @default.
• W2770610507 doi "https://doi.org/10.1136/bmjopen-2017-018758" @default.
• W2770610507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5695307" @default.
• W2770610507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29138210" @default.
• W2770610507 hasPublicationYear "2017" @default.
• W2770610507 type Work @default.
• W2770610507 sameAs 2770610507 @default.
• W2770610507 citedByCount "15" @default.
• W2770610507 countsByYear W27706105072019 @default.
• W2770610507 countsByYear W27706105072020 @default.
• W2770610507 countsByYear W27706105072021 @default.
• W2770610507 countsByYear W27706105072022 @default.
• W2770610507 countsByYear W27706105072023 @default.
• W2770610507 crossrefType "journal-article" @default.
• W2770610507 hasAuthorship W2770610507A5014432451 @default.
• W2770610507 hasAuthorship W2770610507A5014440215 @default.
• W2770610507 hasAuthorship W2770610507A5016560016 @default.
• W2770610507 hasAuthorship W2770610507A5031492399 @default.
• W2770610507 hasAuthorship W2770610507A5032931204 @default.
• W2770610507 hasAuthorship W2770610507A5050220299 @default.
• W2770610507 hasBestOaLocation W27706105071 @default.
• W2770610507 hasConcept C126322002 @default.
• W2770610507 hasConcept C131872663 @default.
• W2770610507 hasConcept C141071460 @default.
• W2770610507 hasConcept C188816634 @default.
• W2770610507 hasConcept C201903717 @default.
• W2770610507 hasConcept C2777696064 @default.
• W2770610507 hasConcept C2778562196 @default.
• W2770610507 hasConcept C2779494336 @default.
• W2770610507 hasConcept C2908933131 @default.
• W2770610507 hasConcept C29456083 @default.
• W2770610507 hasConcept C71924100 @default.
• W2770610507 hasConceptScore W2770610507C126322002 @default.
• W2770610507 hasConceptScore W2770610507C131872663 @default.

• next