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- W2770634204 abstract "Ultracentrifugated compact polyelectrolyte complexes (uCoPECs) represent a new class of materials that are obtained by ultracentrifugation of solutions of polyanion/polycation complexes in the presence of salt. In the present study, two polysaccharides, chitosan and alginate, were used to form such complexes, thus providing a solid material uniquely composed of polysaccharides. The conditions for obtaining the uCoPEC material were optimized: the optimal salt concentration and polysaccharide concentrations were assessed, and the ultracentrifugation speed proved to be a key parameter to obtain compact and homogeneous materials. The Young's modulus, E, of the material was of the order of 12 MPa, which is the highest E value measured for a uCoPEC. The material contained nanometer-sized crystals of chitosan as indicated by X-ray diffraction. Most strikingly, this material proves to be totally cell- and bacteria-resistant. Immunological tests show that this uCoPEC does not induce any proinflammatory response. This makes it a suitable candidate for the development of biocompatible and antifouling biomaterials composed only of polysaccharides." @default.
- W2770634204 created "2017-12-04" @default.
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- W2770634204 date "2017-12-04" @default.
- W2770634204 modified "2023-10-06" @default.
- W2770634204 title "Alginate/Chitosan Compact Polyelectrolyte Complexes: A Cell and Bacterial Repellent Material" @default.
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- W2770634204 doi "https://doi.org/10.1021/acs.chemmater.7b03863" @default.
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