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- W2770700244 abstract "Abstract Objective To describe the clinical presentations of patients diagnosed with ocular adnexal or orbital squamous cell carcinoma ( SCC ), which possess features similar to feline restrictive orbital myofibroblastic sarcoma ( FROMS ). Procedures A retrospective review of adnexal and/or orbital SCC was performed. Cases were collected from the University of Georgia College of Veterinary Medicine and the Comparative Ocular Pathology Laboratory of Wisconsin ( COPLOW ) (1990‐2016). Data included signalment, ophthalmic clinical signs, nonophthalmic history and clinical signs, clinician suspicion of FROMS , advanced imaging results, and subsequent histopathologic diagnosis. FROMS cases from the COPLOW over the same time span were reviewed and compared statistically to the SCC cases with a significance threshold of 0.05. Results Nineteen cases (20 eyes) were identified with adnexal SCC with features similar to FROMS , including keratitis and eyelid/third eyelid restriction and/or thickening. There were no statistically significant differences between clinical findings in the SCC cases and the identified and compared FROMS cases (57 cases; 67 eyes), except for exophthalmos and/or resistance to retropulsion, which was less common in SCC cases (20%) than in FROMS cases (47.8%) ( P = 0.027); and clinical or imaged presence of an overt eyelid or orbital mass, which was more common in the SCC cases (30%) than in the FROMS cases (4.5%) ( P = 0.0010). Conclusions SCC with adnexal involvement has many features similar to FROMS . In addition to FROMS , SCC should be considered a differential diagnosis in cats with restrictive adnexal or orbital signs and corneal changes." @default.
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- W2770700244 date "2017-11-21" @default.
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- W2770700244 title "Orbital invasive squamous cell carcinoma with adnexal involvement clinically mimicking feline restrictive orbital myofibroblastic sarcoma: 19 cases (1990-2016)" @default.
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- W2770700244 doi "https://doi.org/10.1111/vop.12506" @default.
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