FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770768930> ?p ?o ?g. }

• W2770768930 endingPage "119" @default.
• W2770768930 startingPage "113" @default.
• W2770768930 abstract "We previously showed that global brain white matter hyperintensity volume (WMHV) was associated with accelerated long-term functional decline. The objective of the current study was to determine whether WMHV in particular brain regions is more predictive of functional decline.Prospective population-based study.Northern Manhattan magnetic resonance imaging (MRI) study.Individuals free of stroke at baseline (N = 1,195; mean age 71 ± 9; n = 460 (39%) male).Participants had brain MRI with axial T1, T2, and fluid attenuated inversion recovery sequences. Volumetric WMHV distribution across 14 brain regions (brainstem; cerebellum; bilateral frontal, occipital, temporal, and parietal lobes; and bilateral anterior and posterior periventricular white matter (PVWM)) was determined using a combination of bimodal image intensity distribution and atlas-based methods. Participants had annual functional assessments using the Barthel Index (BI) (range 0-100) over a mean of 7.3 years and were followed for stroke, myocardial infarction (MI), and mortality. Because there were multiple collinear variables, least absolute shrinkage and selection operator (LASSO) regression-selected regional WMHV variables most associated with outcomes and adjusted generalized estimating equations models were used to estimate associations with baseline BI and change over time.Using LASSO regularization, only right anterior PVWM was found to meet criteria for selection, and each standard deviation greater WMHV was associated with accelerated functional decline of 0.95 additional BI points per year (95% confidence interval (CI) = -1.20 to -0.70) in an unadjusted model, -0.92 points per year (95% CI = -1.18 to -0.67) with baseline covariate adjustment, and -0.87 points per year (95% CI = -1.12 to -0.62) after adjusting for incident stroke and MI.In this large population-based study with long-term repeated measures of function, periventricular WMHV was particularly associated with accelerated functional decline." @default.
• W2770768930 created "2017-12-04" @default.
• W2770768930 creator A5015545756 @default.
• W2770768930 creator A5016216017 @default.
• W2770768930 creator A5021756508 @default.
• W2770768930 creator A5035331220 @default.
• W2770768930 creator A5044706338 @default.
• W2770768930 creator A5047419602 @default.
• W2770768930 creator A5084539618 @default.
• W2770768930 date "2017-11-20" @default.
• W2770768930 modified "2023-10-15" @default.
• W2770768930 title "Periventricular White Matter Hyperintensities and Functional Decline" @default.
• W2770768930 cites W105952046 @default.
• W2770768930 cites W10901539 @default.
• W2770768930 cites W1519631919 @default.
• W2770768930 cites W1548831745 @default.
• W2770768930 cites W1843498179 @default.
• W2770768930 cites W1853985099 @default.
• W2770768930 cites W1984094638 @default.
• W2770768930 cites W1986159654 @default.
• W2770768930 cites W1987968004 @default.
• W2770768930 cites W1996120720 @default.
• W2770768930 cites W2029182084 @default.
• W2770768930 cites W2033268209 @default.
• W2770768930 cites W203586413 @default.
• W2770768930 cites W2037186395 @default.
• W2770768930 cites W2039231359 @default.
• W2770768930 cites W2041125257 @default.
• W2770768930 cites W2056297302 @default.
• W2770768930 cites W2068709323 @default.
• W2770768930 cites W2071881327 @default.
• W2770768930 cites W2073161926 @default.
• W2770768930 cites W2087625744 @default.
• W2770768930 cites W2089871988 @default.
• W2770768930 cites W2089900126 @default.
• W2770768930 cites W2102182499 @default.
• W2770768930 cites W2103648420 @default.
• W2770768930 cites W2106121313 @default.
• W2770768930 cites W2109412314 @default.
• W2770768930 cites W2122515144 @default.
• W2770768930 cites W2128431628 @default.
• W2770768930 cites W2134172803 @default.
• W2770768930 cites W2136451283 @default.
• W2770768930 cites W2136573752 @default.
• W2770768930 cites W2142735522 @default.
• W2770768930 cites W2146681131 @default.
• W2770768930 cites W2150802909 @default.
• W2770768930 cites W2152164662 @default.
• W2770768930 cites W2172945457 @default.
• W2770768930 cites W2338681188 @default.
• W2770768930 cites W2591660649 @default.
• W2770768930 cites W2768689142 @default.
• W2770768930 cites W2912460163 @default.
• W2770768930 doi "https://doi.org/10.1111/jgs.15149" @default.
• W2770768930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5777880" @default.
• W2770768930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29155435" @default.
• W2770768930 hasPublicationYear "2017" @default.
• W2770768930 type Work @default.
• W2770768930 sameAs 2770768930 @default.
• W2770768930 citedByCount "22" @default.
• W2770768930 countsByYear W27707689302018 @default.
• W2770768930 countsByYear W27707689302019 @default.
• W2770768930 countsByYear W27707689302020 @default.
• W2770768930 countsByYear W27707689302021 @default.
• W2770768930 countsByYear W27707689302022 @default.
• W2770768930 countsByYear W27707689302023 @default.
• W2770768930 crossrefType "journal-article" @default.
• W2770768930 hasAuthorship W2770768930A5015545756 @default.
• W2770768930 hasAuthorship W2770768930A5016216017 @default.
• W2770768930 hasAuthorship W2770768930A5021756508 @default.
• W2770768930 hasAuthorship W2770768930A5035331220 @default.
• W2770768930 hasAuthorship W2770768930A5044706338 @default.
• W2770768930 hasAuthorship W2770768930A5047419602 @default.
• W2770768930 hasAuthorship W2770768930A5084539618 @default.
• W2770768930 hasBestOaLocation W27707689301 @default.
• W2770768930 hasConcept C105795698 @default.
• W2770768930 hasConcept C119043178 @default.
• W2770768930 hasConcept C126322002 @default.
• W2770768930 hasConcept C126838900 @default.
• W2770768930 hasConcept C143409427 @default.
• W2770768930 hasConcept C146638467 @default.
• W2770768930 hasConcept C164705383 @default.
• W2770768930 hasConcept C2781192897 @default.
• W2770768930 hasConcept C2908647359 @default.
• W2770768930 hasConcept C2989005 @default.
• W2770768930 hasConcept C33923547 @default.
• W2770768930 hasConcept C44249647 @default.
• W2770768930 hasConcept C71924100 @default.
• W2770768930 hasConcept C99454951 @default.
• W2770768930 hasConceptScore W2770768930C105795698 @default.
• W2770768930 hasConceptScore W2770768930C119043178 @default.
• W2770768930 hasConceptScore W2770768930C126322002 @default.
• W2770768930 hasConceptScore W2770768930C126838900 @default.
• W2770768930 hasConceptScore W2770768930C143409427 @default.
• W2770768930 hasConceptScore W2770768930C146638467 @default.
• W2770768930 hasConceptScore W2770768930C164705383 @default.
• W2770768930 hasConceptScore W2770768930C2781192897 @default.
• W2770768930 hasConceptScore W2770768930C2908647359 @default.

• next