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- W2770977268 abstract "The primary function of inositol 1,4,5-trisphosphate (InsP3) is to function as a second messenger to release Ca2+ from internal stores. Many cell stimuli act on receptors that are coupled to phospholipase C that hydrolyses phosphatidylinosol 4,5-bisphosphate (PIP2) to release InsP3 to the cytosol. InsP3 receptors located on the endoplasmic reticulum respond to this elevation of InsP3 by releasing Ca2+, which is often organized into characteristic spatial (elementary events and waves) and temporal (Ca2+ oscillations) patterns. This InsP3/Ca2+ pathway has been adapted to control processes as diverse as fertilization, proliferation, contraction, cell metabolism, vesicle and fluid secretion, and information processing in neuronal cells." @default.
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- W2770977268 date "2013-01-01" @default.
- W2770977268 modified "2023-10-16" @default.
- W2770977268 title "Inositol Trisphosphate and Calcium Signaling" @default.
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- W2770977268 doi "https://doi.org/10.1016/b978-0-12-378630-2.00314-5" @default.
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