Matches in SemOpenAlex for { <https://semopenalex.org/work/W2771303589> ?p ?o ?g. }
- W2771303589 abstract "To better understand the effects of a diet high in fat, sugar, and sodium on cerebrovascular function, Sprague Dawley rats were chronically exposed to a Cafeteria diet. Resting cerebral perfusion and cerebrovascular reactivity was quantified using continuous arterial spin labeling (CASL) magnetic resonance imaging (MRI). In addition, structural changes to the cerebrovasculature and susceptibility to ischemic lesion were examined. Compared to control animals fed standard chow (SD), Cafeteria diet (CAF) rats exhibited increased resting brain perfusion in the hippocampus and reduced cerebrovascular reactivity in response to 10% inspired CO2 challenges in both the hippocampus and the neocortex. CAF rats switched to chow for one month (SWT) exhibited improved resting perfusion in the hippocampus as well as improved cerebrovascular reactivity in the neocortex. However, the diet switch did not correct cerebrovascular reactivity in the hippocampus. These changes were not accompanied by alterations in the structural integrity of the cerebral microvasculature, examined using rat endothelial cell antigen-1 (RECA-1) and immunoglobulin G (IgG) immunostaining. Also, the extent of tissue damage induced by endothelin-1 injection into sensorimotor cortex was not affected by the Cafeteria diet. These results demonstrate that short-term consumption of an ultra-processed diet reduces cerebrovascular reactivity. This effect persists after dietary normalization despite recovery of peripheral symptomatology." @default.
- W2771303589 created "2017-12-22" @default.
- W2771303589 creator A5036949934 @default.
- W2771303589 creator A5041218352 @default.
- W2771303589 creator A5047765476 @default.
- W2771303589 creator A5054588526 @default.
- W2771303589 creator A5083489983 @default.
- W2771303589 creator A5084885023 @default.
- W2771303589 creator A5088635351 @default.
- W2771303589 creator A5004632189 @default.
- W2771303589 date "2018-02-01" @default.
- W2771303589 modified "2023-09-27" @default.
- W2771303589 title "Reduced Cerebrovascular Reactivity and Increased Resting Cerebral Perfusion in Rats Exposed to a Cafeteria Diet" @default.
- W2771303589 cites W1502898407 @default.
- W2771303589 cites W1668104130 @default.
- W2771303589 cites W175679200 @default.
- W2771303589 cites W1834081378 @default.
- W2771303589 cites W1871920786 @default.
- W2771303589 cites W1951724000 @default.
- W2771303589 cites W1967239550 @default.
- W2771303589 cites W1971716779 @default.
- W2771303589 cites W1982703569 @default.
- W2771303589 cites W1985884903 @default.
- W2771303589 cites W1992477463 @default.
- W2771303589 cites W1994524645 @default.
- W2771303589 cites W1997493159 @default.
- W2771303589 cites W2000450302 @default.
- W2771303589 cites W2002680203 @default.
- W2771303589 cites W2011103593 @default.
- W2771303589 cites W2012955685 @default.
- W2771303589 cites W2027508239 @default.
- W2771303589 cites W2028472802 @default.
- W2771303589 cites W2034292395 @default.
- W2771303589 cites W2036811411 @default.
- W2771303589 cites W2040878113 @default.
- W2771303589 cites W2042133266 @default.
- W2771303589 cites W2043370834 @default.
- W2771303589 cites W2043947812 @default.
- W2771303589 cites W2046518021 @default.
- W2771303589 cites W2050749363 @default.
- W2771303589 cites W2052687370 @default.
- W2771303589 cites W2058553880 @default.
- W2771303589 cites W2062870118 @default.
- W2771303589 cites W2072744514 @default.
- W2771303589 cites W2072915957 @default.
- W2771303589 cites W2083900005 @default.
- W2771303589 cites W2089798586 @default.
- W2771303589 cites W2089899502 @default.
- W2771303589 cites W2092669425 @default.
- W2771303589 cites W2096491557 @default.
- W2771303589 cites W2106322754 @default.
- W2771303589 cites W2107073645 @default.
- W2771303589 cites W2108999728 @default.
- W2771303589 cites W2109357385 @default.
- W2771303589 cites W2109644106 @default.
- W2771303589 cites W2110147352 @default.
- W2771303589 cites W2111719492 @default.
- W2771303589 cites W2121890486 @default.
- W2771303589 cites W2124967984 @default.
- W2771303589 cites W2131565364 @default.
- W2771303589 cites W2135158617 @default.
- W2771303589 cites W2136317345 @default.
- W2771303589 cites W2140560962 @default.
- W2771303589 cites W2143104968 @default.
- W2771303589 cites W2143167585 @default.
- W2771303589 cites W2153792184 @default.
- W2771303589 cites W2154348565 @default.
- W2771303589 cites W2162547471 @default.
- W2771303589 cites W2163815564 @default.
- W2771303589 cites W2169268292 @default.
- W2771303589 cites W2226817873 @default.
- W2771303589 cites W2229344867 @default.
- W2771303589 cites W2235774707 @default.
- W2771303589 cites W2342723962 @default.
- W2771303589 cites W2402088499 @default.
- W2771303589 cites W2529361286 @default.
- W2771303589 doi "https://doi.org/10.1016/j.neuroscience.2017.11.054" @default.
- W2771303589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29229555" @default.
- W2771303589 hasPublicationYear "2018" @default.
- W2771303589 type Work @default.
- W2771303589 sameAs 2771303589 @default.
- W2771303589 citedByCount "6" @default.
- W2771303589 countsByYear W27713035892018 @default.
- W2771303589 countsByYear W27713035892020 @default.
- W2771303589 countsByYear W27713035892022 @default.
- W2771303589 countsByYear W27713035892023 @default.
- W2771303589 crossrefType "journal-article" @default.
- W2771303589 hasAuthorship W2771303589A5004632189 @default.
- W2771303589 hasAuthorship W2771303589A5036949934 @default.
- W2771303589 hasAuthorship W2771303589A5041218352 @default.
- W2771303589 hasAuthorship W2771303589A5047765476 @default.
- W2771303589 hasAuthorship W2771303589A5054588526 @default.
- W2771303589 hasAuthorship W2771303589A5083489983 @default.
- W2771303589 hasAuthorship W2771303589A5084885023 @default.
- W2771303589 hasAuthorship W2771303589A5088635351 @default.
- W2771303589 hasConcept C126322002 @default.
- W2771303589 hasConcept C134018914 @default.
- W2771303589 hasConcept C142724271 @default.
- W2771303589 hasConcept C146957229 @default.
- W2771303589 hasConcept C148762608 @default.