FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2771561797> ?p ?o ?g. }

• W2771561797 abstract "ABSTRACT Cryptococcosis occurs most frequently in immunocompromised individuals. This has led to the prevailing view that this disease is the result of weak immune responses that cannot control the fungus. However, increasingly, clinical and experimental studies have revealed that the host immune response can contribute to cryptococcal pathogenesis, including the recent study of L. M. Neal et al. (mBio 8:e01415-17, 2017, https://doi.org/10.1128/mBio.01415-17 ) that reports that CD4 + T cells mediate tissue damage in experimental murine cryptococcosis. This finding has fundamental implications for our understanding of the pathogenesis of cryptococcal disease; it helps explain why immunotherapy has been largely unsuccessful in treatment and provides insight into the paradoxical observation that HIV-associated cryptococcosis may have a better prognosis than cryptococcosis in those with no known immune impairment. The demonstration that host-mediated damage can drive cryptococcal disease provides proof of concept that the parabola put forth in the damage-response framework has the flexibility to depict complex and changing outcomes of host-microbe interaction." @default.
• W2771561797 created "2017-12-22" @default.
• W2771561797 creator A5016903148 @default.
• W2771561797 creator A5077902719 @default.
• W2771561797 date "2017-12-29" @default.
• W2771561797 modified "2023-09-28" @default.
• W2771561797 title "Immune-Mediated Damage Completes the Parabola: <i>Cryptococcus neoformans</i> Pathogenesis Can Reflect the Outcome of a Weak or Strong Immune Response" @default.
• W2771561797 cites W1506388750 @default.
• W2771561797 cites W1892054757 @default.
• W2771561797 cites W1908791257 @default.
• W2771561797 cites W1965093440 @default.
• W2771561797 cites W1978597348 @default.
• W2771561797 cites W2047505752 @default.
• W2771561797 cites W2054253853 @default.
• W2771561797 cites W2063902084 @default.
• W2771561797 cites W2080611668 @default.
• W2771561797 cites W2099198339 @default.
• W2771561797 cites W2107409415 @default.
• W2771561797 cites W2111345804 @default.
• W2771561797 cites W2111962782 @default.
• W2771561797 cites W2114419181 @default.
• W2771561797 cites W2117826414 @default.
• W2771561797 cites W2120465011 @default.
• W2771561797 cites W2127330103 @default.
• W2771561797 cites W2139205960 @default.
• W2771561797 cites W2147068333 @default.
• W2771561797 cites W2147314396 @default.
• W2771561797 cites W2147323935 @default.
• W2771561797 cites W2148956152 @default.
• W2771561797 cites W2154447377 @default.
• W2771561797 cites W2159361186 @default.
• W2771561797 cites W2161004182 @default.
• W2771561797 cites W2161157918 @default.
• W2771561797 cites W2168373615 @default.
• W2771561797 cites W2172094855 @default.
• W2771561797 cites W2267121933 @default.
• W2771561797 cites W2277731646 @default.
• W2771561797 cites W2409154810 @default.
• W2771561797 cites W2414962288 @default.
• W2771561797 cites W2621474592 @default.
• W2771561797 cites W2748655201 @default.
• W2771561797 cites W2770408307 @default.
• W2771561797 doi "https://doi.org/10.1128/mbio.02063-17" @default.
• W2771561797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5727418" @default.
• W2771561797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29233901" @default.
• W2771561797 hasPublicationYear "2017" @default.
• W2771561797 type Work @default.
• W2771561797 sameAs 2771561797 @default.
• W2771561797 citedByCount "54" @default.
• W2771561797 countsByYear W27715617972018 @default.
• W2771561797 countsByYear W27715617972019 @default.
• W2771561797 countsByYear W27715617972020 @default.
• W2771561797 countsByYear W27715617972021 @default.
• W2771561797 countsByYear W27715617972022 @default.
• W2771561797 countsByYear W27715617972023 @default.
• W2771561797 crossrefType "journal-article" @default.
• W2771561797 hasAuthorship W2771561797A5016903148 @default.
• W2771561797 hasAuthorship W2771561797A5077902719 @default.
• W2771561797 hasBestOaLocation W27715617971 @default.
• W2771561797 hasConcept C142724271 @default.
• W2771561797 hasConcept C203014093 @default.
• W2771561797 hasConcept C2777701055 @default.
• W2771561797 hasConcept C2777893358 @default.
• W2771561797 hasConcept C2778952914 @default.
• W2771561797 hasConcept C2779134260 @default.
• W2771561797 hasConcept C2779413141 @default.
• W2771561797 hasConcept C2780942790 @default.
• W2771561797 hasConcept C2994443828 @default.
• W2771561797 hasConcept C71924100 @default.
• W2771561797 hasConcept C86803240 @default.
• W2771561797 hasConcept C8891405 @default.
• W2771561797 hasConcept C89423630 @default.
• W2771561797 hasConceptScore W2771561797C142724271 @default.
• W2771561797 hasConceptScore W2771561797C203014093 @default.
• W2771561797 hasConceptScore W2771561797C2777701055 @default.
• W2771561797 hasConceptScore W2771561797C2777893358 @default.
• W2771561797 hasConceptScore W2771561797C2778952914 @default.
• W2771561797 hasConceptScore W2771561797C2779134260 @default.
• W2771561797 hasConceptScore W2771561797C2779413141 @default.
• W2771561797 hasConceptScore W2771561797C2780942790 @default.
• W2771561797 hasConceptScore W2771561797C2994443828 @default.
• W2771561797 hasConceptScore W2771561797C71924100 @default.
• W2771561797 hasConceptScore W2771561797C86803240 @default.
• W2771561797 hasConceptScore W2771561797C8891405 @default.
• W2771561797 hasConceptScore W2771561797C89423630 @default.
• W2771561797 hasFunder F4320337355 @default.
• W2771561797 hasIssue "6" @default.
• W2771561797 hasLocation W27715617971 @default.
• W2771561797 hasLocation W27715617972 @default.
• W2771561797 hasLocation W27715617973 @default.
• W2771561797 hasLocation W27715617974 @default.
• W2771561797 hasLocation W27715617975 @default.
• W2771561797 hasOpenAccess W2771561797 @default.
• W2771561797 hasPrimaryLocation W27715617971 @default.
• W2771561797 hasRelatedWork W1997824320 @default.
• W2771561797 hasRelatedWork W2104565935 @default.
• W2771561797 hasRelatedWork W2124593326 @default.
• W2771561797 hasRelatedWork W2131232351 @default.
• W2771561797 hasRelatedWork W2139873095 @default.
• W2771561797 hasRelatedWork W2161358734 @default.

• next