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• W2771652005 abstract "Abstract We show that CO 2 can be converted by an engineered “Knallgas” bacterium ( Cupriavidus necator ) into the terpene α‐humulene. Heterologous expression of the mevalonate pathway and α‐humulene synthase resulted in the production of approximately 10 mg α‐humulene per gram cell dry mass (CDW) under heterotrophic conditions. This first example of chemolithoautotrophic production of a terpene from carbon dioxide, hydrogen, and oxygen is a promising starting point for the production of different high‐value terpene compounds from abundant and simple raw materials. Furthermore, the production system was used to produce 17 mg α‐humulene per gram CDW from CO 2 and electrical energy in microbial electrosynthesis (MES) mode. Given that the system can convert CO 2 by using electrical energy from solar energy, it opens a new route to artificial photosynthetic systems." @default.
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• W2771652005 date "2018-01-15" @default.
• W2771652005 modified "2023-10-11" @default.
• W2771652005 title "CO₂ to Terpenes: Autotrophic and Electroautotrophic α‐Humulene Production with <i>Cupriavidus necator</i>" @default.
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• W2771652005 doi "https://doi.org/10.1002/anie.201711302" @default.
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