Matches in SemOpenAlex for { <https://semopenalex.org/work/W2771796238> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2771796238 endingPage "1436" @default.
- W2771796238 startingPage "1433" @default.
- W2771796238 abstract "Background Currently, treatment of latent tuberculosis infection (LTBI) in Australia consists most commonly of a 9-month course of isoniazid (9H). A 3-month course of weekly isoniazid and rifapentine (3HP) has been shown to be as effective as 9 months of daily isoniazid, and associated with less hepatotoxicity; however, rifapentine is not currently available in Australia. Introduction of this regimen would have apparent advantages for people with LTBI in Victoria by safely shortening duration of LTBI therapy. However, the cost benefit of this new therapeutic approach is uncertain. Aim Cost-analysis of standard and short-course therapy for LTBI in an Australian context. Methods Single-centre randomised controlled trial conducted between December 2013-March 2016. Participants underwent 1:1 randomisation to either a 9-month course of daily isoniazid or a 12-week course of weekly isoniazid and rifapentine. The primary outcome measure was total healthcare system costs (in Australian dollars; AUD) per completed course of LTBI therapy. Secondary cost analyses were performed to consider varying assumptions regarding commercial cost of rifapentine. Results Overall, 34 of 40 (85%) participants in the 9H group and 36/40 (90%) in the 3HR group completed therapy. One patient in the 3HP group was hospitalised for a febrile illness; no hospitalisations were recorded in the 9H group. The cost per completed course of 9H was 601 AUD, while that of 3HP was significantly lower at 511 AUD (P < 0.01). Conclusions This study provides cost analysis evidence to support the use of 3HP for the treatment of LTBI in Australia." @default.
- W2771796238 created "2017-12-22" @default.
- W2771796238 creator A5000873682 @default.
- W2771796238 creator A5004669472 @default.
- W2771796238 creator A5018948650 @default.
- W2771796238 creator A5021448672 @default.
- W2771796238 creator A5031283280 @default.
- W2771796238 creator A5042406854 @default.
- W2771796238 creator A5045440716 @default.
- W2771796238 creator A5052273880 @default.
- W2771796238 creator A5090536514 @default.
- W2771796238 date "2017-12-01" @default.
- W2771796238 modified "2023-09-23" @default.
- W2771796238 title "SIRCLE: a randomised controlled cost comparison of self-administered short-course isoniazid and rifapentine for cost-effective latent tuberculosis eradication" @default.
- W2771796238 cites W1541783454 @default.
- W2771796238 cites W1980075079 @default.
- W2771796238 cites W2043904209 @default.
- W2771796238 cites W2110778369 @default.
- W2771796238 cites W2148232746 @default.
- W2771796238 cites W2166822423 @default.
- W2771796238 cites W2184272173 @default.
- W2771796238 cites W2278425353 @default.
- W2771796238 cites W2325984955 @default.
- W2771796238 cites W2326547503 @default.
- W2771796238 cites W2334365448 @default.
- W2771796238 cites W2949583887 @default.
- W2771796238 doi "https://doi.org/10.1111/imj.13601" @default.
- W2771796238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29224209" @default.
- W2771796238 hasPublicationYear "2017" @default.
- W2771796238 type Work @default.
- W2771796238 sameAs 2771796238 @default.
- W2771796238 citedByCount "8" @default.
- W2771796238 countsByYear W27717962382018 @default.
- W2771796238 countsByYear W27717962382020 @default.
- W2771796238 countsByYear W27717962382021 @default.
- W2771796238 countsByYear W27717962382022 @default.
- W2771796238 countsByYear W27717962382023 @default.
- W2771796238 crossrefType "journal-article" @default.
- W2771796238 hasAuthorship W2771796238A5000873682 @default.
- W2771796238 hasAuthorship W2771796238A5004669472 @default.
- W2771796238 hasAuthorship W2771796238A5018948650 @default.
- W2771796238 hasAuthorship W2771796238A5021448672 @default.
- W2771796238 hasAuthorship W2771796238A5031283280 @default.
- W2771796238 hasAuthorship W2771796238A5042406854 @default.
- W2771796238 hasAuthorship W2771796238A5045440716 @default.
- W2771796238 hasAuthorship W2771796238A5052273880 @default.
- W2771796238 hasAuthorship W2771796238A5090536514 @default.
- W2771796238 hasBestOaLocation W27717962382 @default.
- W2771796238 hasConcept C126322002 @default.
- W2771796238 hasConcept C141071460 @default.
- W2771796238 hasConcept C142724271 @default.
- W2771796238 hasConcept C168563851 @default.
- W2771796238 hasConcept C187212893 @default.
- W2771796238 hasConcept C2776967927 @default.
- W2771796238 hasConcept C2776991065 @default.
- W2771796238 hasConcept C2777975735 @default.
- W2771796238 hasConcept C2779806340 @default.
- W2771796238 hasConcept C2780159726 @default.
- W2771796238 hasConcept C2781069245 @default.
- W2771796238 hasConcept C2781413609 @default.
- W2771796238 hasConcept C71924100 @default.
- W2771796238 hasConceptScore W2771796238C126322002 @default.
- W2771796238 hasConceptScore W2771796238C141071460 @default.
- W2771796238 hasConceptScore W2771796238C142724271 @default.
- W2771796238 hasConceptScore W2771796238C168563851 @default.
- W2771796238 hasConceptScore W2771796238C187212893 @default.
- W2771796238 hasConceptScore W2771796238C2776967927 @default.
- W2771796238 hasConceptScore W2771796238C2776991065 @default.
- W2771796238 hasConceptScore W2771796238C2777975735 @default.
- W2771796238 hasConceptScore W2771796238C2779806340 @default.
- W2771796238 hasConceptScore W2771796238C2780159726 @default.
- W2771796238 hasConceptScore W2771796238C2781069245 @default.
- W2771796238 hasConceptScore W2771796238C2781413609 @default.
- W2771796238 hasConceptScore W2771796238C71924100 @default.
- W2771796238 hasIssue "12" @default.
- W2771796238 hasLocation W27717962381 @default.
- W2771796238 hasLocation W27717962382 @default.
- W2771796238 hasLocation W27717962383 @default.
- W2771796238 hasOpenAccess W2771796238 @default.
- W2771796238 hasPrimaryLocation W27717962381 @default.
- W2771796238 hasRelatedWork W2038904221 @default.
- W2771796238 hasRelatedWork W2050876043 @default.
- W2771796238 hasRelatedWork W2125648033 @default.
- W2771796238 hasRelatedWork W2144322909 @default.
- W2771796238 hasRelatedWork W2516710169 @default.
- W2771796238 hasRelatedWork W2582313469 @default.
- W2771796238 hasRelatedWork W2767923653 @default.
- W2771796238 hasRelatedWork W3137262505 @default.
- W2771796238 hasRelatedWork W4295706067 @default.
- W2771796238 hasRelatedWork W4380370656 @default.
- W2771796238 hasVolume "47" @default.
- W2771796238 isParatext "false" @default.
- W2771796238 isRetracted "false" @default.
- W2771796238 magId "2771796238" @default.
- W2771796238 workType "article" @default.