FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2771904265> ?p ?o ?g. }

• W2771904265 abstract "Abstract Previous studies suggest that leptin (LEP) has an important role in glucose metabolism in the nonpregnant state. During pregnancy, circulating maternal concentrations of leptin rise significantly, mainly due to increased secretion of leptin from maternal adipose tissue and placenta. This study aimed to analyze the impact of maternal and fetal common LEP variants on glucose homeostasis in the pregnant state. Several glycemic traits, including fasting plasma glucose, fasting plasma insulin (FPI), and plasma glucose 1 hour after a 50-g oral glucose load, were measured in 1,112 unrelated Chinese Han pregnant women at 24–28 weeks gestation. Homeostatic model assessment (HOMA) was used to assess beta cell function (HOMA1-β and HOMA2-β) and insulin resistance (HOMA1-IR and HOMA2-IR).The relationships between glycemic traits and 12 LEP variants were determined. After applying the Bonferroni correction, we detected that (1) maternal rs10954173 and fetal rs10244329 were associated with maternal FPI although the effect of fetal rs10244329 may be not independent of maternal rs10244329, and (2) maternal rs12537573 was associated with maternal FPI and HOMA2-IR. This study provides genetic evidence that both maternal and fetal LEP polymorphisms may affect maternal glucose metabolism in pregnancy." @default.
• W2771904265 created "2017-12-22" @default.
• W2771904265 creator A5006909809 @default.
• W2771904265 creator A5015462122 @default.
• W2771904265 creator A5029636776 @default.
• W2771904265 creator A5033393620 @default.
• W2771904265 creator A5036859784 @default.
• W2771904265 creator A5069030526 @default.
• W2771904265 creator A5083666748 @default.
• W2771904265 creator A5091838611 @default.
• W2771904265 date "2017-12-18" @default.
• W2771904265 modified "2023-09-23" @default.
• W2771904265 title "Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy" @default.
• W2771904265 cites W1536987359 @default.
• W2771904265 cites W1554432647 @default.
• W2771904265 cites W1592674309 @default.
• W2771904265 cites W1631449371 @default.
• W2771904265 cites W1887831276 @default.
• W2771904265 cites W1901760383 @default.
• W2771904265 cites W1969858460 @default.
• W2771904265 cites W1981583644 @default.
• W2771904265 cites W1981677358 @default.
• W2771904265 cites W1992953906 @default.
• W2771904265 cites W1999575197 @default.
• W2771904265 cites W2013799006 @default.
• W2771904265 cites W2016972371 @default.
• W2771904265 cites W2017485612 @default.
• W2771904265 cites W2019134967 @default.
• W2771904265 cites W2027531062 @default.
• W2771904265 cites W2042760540 @default.
• W2771904265 cites W2054945495 @default.
• W2771904265 cites W2056251384 @default.
• W2771904265 cites W2059015027 @default.
• W2771904265 cites W2072700176 @default.
• W2771904265 cites W2076134327 @default.
• W2771904265 cites W2090390027 @default.
• W2771904265 cites W2100028812 @default.
• W2771904265 cites W2101921785 @default.
• W2771904265 cites W2104549677 @default.
• W2771904265 cites W2105912552 @default.
• W2771904265 cites W2109937108 @default.
• W2771904265 cites W2124620553 @default.
• W2771904265 cites W2134644953 @default.
• W2771904265 cites W2138116074 @default.
• W2771904265 cites W2148316821 @default.
• W2771904265 cites W2153479757 @default.
• W2771904265 cites W2153651314 @default.
• W2771904265 cites W2156353972 @default.
• W2771904265 cites W2160859576 @default.
• W2771904265 cites W2169890072 @default.
• W2771904265 cites W2182343999 @default.
• W2771904265 cites W2607031541 @default.
• W2771904265 cites W4205677347 @default.
• W2771904265 cites W4241883936 @default.
• W2771904265 doi "https://doi.org/10.1038/s41598-017-18117-z" @default.
• W2771904265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5735190" @default.
• W2771904265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29255202" @default.
• W2771904265 hasPublicationYear "2017" @default.
• W2771904265 type Work @default.
• W2771904265 sameAs 2771904265 @default.
• W2771904265 citedByCount "3" @default.
• W2771904265 countsByYear W27719042652019 @default.
• W2771904265 countsByYear W27719042652020 @default.
• W2771904265 countsByYear W27719042652023 @default.
• W2771904265 crossrefType "journal-article" @default.
• W2771904265 hasAuthorship W2771904265A5006909809 @default.
• W2771904265 hasAuthorship W2771904265A5015462122 @default.
• W2771904265 hasAuthorship W2771904265A5029636776 @default.
• W2771904265 hasAuthorship W2771904265A5033393620 @default.
• W2771904265 hasAuthorship W2771904265A5036859784 @default.
• W2771904265 hasAuthorship W2771904265A5069030526 @default.
• W2771904265 hasAuthorship W2771904265A5083666748 @default.
• W2771904265 hasAuthorship W2771904265A5091838611 @default.
• W2771904265 hasBestOaLocation W27719042651 @default.
• W2771904265 hasConcept C126322002 @default.
• W2771904265 hasConcept C134018914 @default.
• W2771904265 hasConcept C17093226 @default.
• W2771904265 hasConcept C171089720 @default.
• W2771904265 hasConcept C172680121 @default.
• W2771904265 hasConcept C2776953305 @default.
• W2771904265 hasConcept C2777391703 @default.
• W2771904265 hasConcept C2779234561 @default.
• W2771904265 hasConcept C2779306644 @default.
• W2771904265 hasConcept C2780473172 @default.
• W2771904265 hasConcept C2780613262 @default.
• W2771904265 hasConcept C3018667095 @default.
• W2771904265 hasConcept C511355011 @default.
• W2771904265 hasConcept C54355233 @default.
• W2771904265 hasConcept C71924100 @default.
• W2771904265 hasConcept C86803240 @default.
• W2771904265 hasConceptScore W2771904265C126322002 @default.
• W2771904265 hasConceptScore W2771904265C134018914 @default.
• W2771904265 hasConceptScore W2771904265C17093226 @default.
• W2771904265 hasConceptScore W2771904265C171089720 @default.
• W2771904265 hasConceptScore W2771904265C172680121 @default.
• W2771904265 hasConceptScore W2771904265C2776953305 @default.
• W2771904265 hasConceptScore W2771904265C2777391703 @default.
• W2771904265 hasConceptScore W2771904265C2779234561 @default.
• W2771904265 hasConceptScore W2771904265C2779306644 @default.
• W2771904265 hasConceptScore W2771904265C2780473172 @default.

• next