FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2772064801> ?p ?o ?g. }

• W2772064801 endingPage "371" @default.
• W2772064801 startingPage "371" @default.
• W2772064801 abstract "Brain metastasis is considered rare in metastatic colorectal cancer (mCRC); thus, surveillance imaging does not routinely include the brain. The reported incidence of brain metastases ranges from 0.6% to 3.2%.The South Australian mCRC Registry (SAmCRC) was analyzed to assess the number of patients presenting with brain metastasis during their lifetime. Due to small numbers, a descriptive analysis is presented.Only 59 patients of 4,100 on the registry at the time of analysis had developed brain metastasis (1.4%). The clinical characteristics of those with brain metastasis were as follows: the median age was 65.3 years and 51% were female. Where the V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation status of the tumor was known, the majority harbored a KRAS mutation (55%); 31 (53%) underwent craniotomy and 55 (93%) underwent whole-brain radiotherapy. The median survival time from diagnosis of brain metastasis was 4.2 months (95% confidence interval 2.9-5.5). Patients who underwent craniotomy and radiotherapy had superior survival compared to those who underwent whole-brain radiotherapy (8.5 months vs. 2.2 months, respectively). Data from the SAmCRC (a population-based registry) confirm that brain metastases are rare and the median time to development is approximately 2 years.Brain metastasis is a rare outcome in advanced CRC. Patients within the registry tended to be female, young in age, and harbored with higher rates of KRAS mutations. Whether routine surveillance brain scanning should be considered remains controversial given the relative rarity of developing brain metastases in mCRC and ultimately, most patients with central nervous system involvement die from their extracranial disease." @default.
• W2772064801 created "2017-12-22" @default.
• W2772064801 creator A5005513857 @default.
• W2772064801 creator A5007684406 @default.
• W2772064801 creator A5035165249 @default.
• W2772064801 creator A5048682770 @default.
• W2772064801 creator A5061460550 @default.
• W2772064801 creator A5068720728 @default.
• W2772064801 creator A5070238121 @default.
• W2772064801 creator A5079190511 @default.
• W2772064801 creator A5082298944 @default.
• W2772064801 creator A5086946129 @default.
• W2772064801 creator A5090988352 @default.
• W2772064801 date "2017-01-01" @default.
• W2772064801 modified "2023-10-13" @default.
• W2772064801 title "Brain metastasis in advanced colorectal cancer: results from the South Australian metastatic colorectal cancer (SAmCRC) registry" @default.
• W2772064801 cites W1480056457 @default.
• W2772064801 cites W1492286179 @default.
• W2772064801 cites W1514077574 @default.
• W2772064801 cites W1518850804 @default.
• W2772064801 cites W1986195579 @default.
• W2772064801 cites W1991910930 @default.
• W2772064801 cites W1993456867 @default.
• W2772064801 cites W2012767846 @default.
• W2772064801 cites W2013195627 @default.
• W2772064801 cites W2017648402 @default.
• W2772064801 cites W2022428794 @default.
• W2772064801 cites W2023988458 @default.
• W2772064801 cites W2026152461 @default.
• W2772064801 cites W2032537620 @default.
• W2772064801 cites W2038202392 @default.
• W2772064801 cites W2065225411 @default.
• W2772064801 cites W2069392276 @default.
• W2772064801 cites W2072219397 @default.
• W2772064801 cites W2077428590 @default.
• W2772064801 cites W2093649059 @default.
• W2772064801 cites W2101493293 @default.
• W2772064801 cites W2102601309 @default.
• W2772064801 cites W2103789431 @default.
• W2772064801 cites W2116652221 @default.
• W2772064801 cites W2125945503 @default.
• W2772064801 cites W2138885918 @default.
• W2772064801 cites W2142479365 @default.
• W2772064801 cites W2143980344 @default.
• W2772064801 cites W2157416388 @default.
• W2772064801 cites W2399102496 @default.
• W2772064801 doi "https://doi.org/10.20892/j.issn.2095-3941.2017.0068" @default.
• W2772064801 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5785167" @default.
• W2772064801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29372103" @default.
• W2772064801 hasPublicationYear "2017" @default.
• W2772064801 type Work @default.
• W2772064801 sameAs 2772064801 @default.
• W2772064801 citedByCount "16" @default.
• W2772064801 countsByYear W27720648012018 @default.
• W2772064801 countsByYear W27720648012019 @default.
• W2772064801 countsByYear W27720648012020 @default.
• W2772064801 countsByYear W27720648012021 @default.
• W2772064801 countsByYear W27720648012022 @default.
• W2772064801 countsByYear W27720648012023 @default.
• W2772064801 crossrefType "journal-article" @default.
• W2772064801 hasAuthorship W2772064801A5005513857 @default.
• W2772064801 hasAuthorship W2772064801A5007684406 @default.
• W2772064801 hasAuthorship W2772064801A5035165249 @default.
• W2772064801 hasAuthorship W2772064801A5048682770 @default.
• W2772064801 hasAuthorship W2772064801A5061460550 @default.
• W2772064801 hasAuthorship W2772064801A5068720728 @default.
• W2772064801 hasAuthorship W2772064801A5070238121 @default.
• W2772064801 hasAuthorship W2772064801A5079190511 @default.
• W2772064801 hasAuthorship W2772064801A5082298944 @default.
• W2772064801 hasAuthorship W2772064801A5086946129 @default.
• W2772064801 hasAuthorship W2772064801A5090988352 @default.
• W2772064801 hasBestOaLocation W27720648011 @default.
• W2772064801 hasConcept C120665830 @default.
• W2772064801 hasConcept C121332964 @default.
• W2772064801 hasConcept C121608353 @default.
• W2772064801 hasConcept C126322002 @default.
• W2772064801 hasConcept C126838900 @default.
• W2772064801 hasConcept C143998085 @default.
• W2772064801 hasConcept C2778164965 @default.
• W2772064801 hasConcept C2778527826 @default.
• W2772064801 hasConcept C2778871575 @default.
• W2772064801 hasConcept C2779013556 @default.
• W2772064801 hasConcept C2781187634 @default.
• W2772064801 hasConcept C2908647359 @default.
• W2772064801 hasConcept C509974204 @default.
• W2772064801 hasConcept C526805850 @default.
• W2772064801 hasConcept C61511704 @default.
• W2772064801 hasConcept C71924100 @default.
• W2772064801 hasConcept C99454951 @default.
• W2772064801 hasConceptScore W2772064801C120665830 @default.
• W2772064801 hasConceptScore W2772064801C121332964 @default.
• W2772064801 hasConceptScore W2772064801C121608353 @default.
• W2772064801 hasConceptScore W2772064801C126322002 @default.
• W2772064801 hasConceptScore W2772064801C126838900 @default.
• W2772064801 hasConceptScore W2772064801C143998085 @default.
• W2772064801 hasConceptScore W2772064801C2778164965 @default.
• W2772064801 hasConceptScore W2772064801C2778527826 @default.
• W2772064801 hasConceptScore W2772064801C2778871575 @default.

• next