FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2772073186> ?p ?o ?g. }

• W2772073186 abstract "Melasma is a characteristic pattern of facial hyperpigmentation, occurring primarily on the forehead, cheeks, and chin, in a mask-like distribution. The pathogenesis of melasma is not fully understood. Vitamin D plays a role in skin pigmentation. It exerts its effect through vitamin D receptor (VDR), which is expressed in variable cells including normal melanocytes.The aim of the current work was to investigate if VDR gene polymorphism (TaqI) confers susceptibility to melasma in Egyptian patients.A total of 45 female patients with melasma were recruited and 50 healthy subjects that were matched on age, sex, body mass index, and skin phototype, were included as a control group. TaqI polymorphism was investigated using restriction fragment length polymorphism polymerase chain reaction (RFLP PCR).Presence of (t) allele and (tt) genotype was significantly associated with melasma cases compared with control group (P < 0.001 for both). No significant association was found between (tt) genotype or (t) allele and clinical data of the studied cases.TaqI polymorphism is associated with melasma. Further, large-scale studies are recommended to underscore and validate the current findings. It is also necessary for future studies to extend the research to other populations and ethnicities. Investigating other VDR gene polymorphisms in melasma is also warranted. Since melasma is a multifactorial disease, gene-gene and gene-environment interactions should be considered in future genetic-epidemiologic researches to apply more comprehensive insight into the role of VDR gene in its pathogenesis." @default.
• W2772073186 created "2017-12-22" @default.
• W2772073186 creator A5002253998 @default.
• W2772073186 creator A5045183822 @default.
• W2772073186 creator A5074609595 @default.
• W2772073186 creator A5076154362 @default.
• W2772073186 date "2017-01-01" @default.
• W2772073186 modified "2023-09-23" @default.
• W2772073186 title "Identification of genotypes and allelic frequencies of vitamin D receptor gene polymorphism (TaqI) in egyptian melasma patients" @default.
• W2772073186 cites W1965485451 @default.
• W2772073186 cites W1981757494 @default.
• W2772073186 cites W2001930576 @default.
• W2772073186 cites W2007158870 @default.
• W2772073186 cites W2009180025 @default.
• W2772073186 cites W2011712218 @default.
• W2772073186 cites W2012171191 @default.
• W2772073186 cites W2013402282 @default.
• W2772073186 cites W2029724839 @default.
• W2772073186 cites W2038308015 @default.
• W2772073186 cites W2047681882 @default.
• W2772073186 cites W2050730569 @default.
• W2772073186 cites W2055984976 @default.
• W2772073186 cites W2073870011 @default.
• W2772073186 cites W2095351093 @default.
• W2772073186 cites W2107520088 @default.
• W2772073186 cites W2116565400 @default.
• W2772073186 cites W2120241921 @default.
• W2772073186 cites W2141218945 @default.
• W2772073186 cites W2153488515 @default.
• W2772073186 cites W2154616649 @default.
• W2772073186 cites W2161361832 @default.
• W2772073186 cites W2166517626 @default.
• W2772073186 cites W2170642623 @default.
• W2772073186 cites W2171469662 @default.
• W2772073186 cites W2235580196 @default.
• W2772073186 cites W2286818936 @default.
• W2772073186 cites W2476542314 @default.
• W2772073186 cites W4234516304 @default.
• W2772073186 doi "https://doi.org/10.4103/idoj.idoj_363_16" @default.
• W2772073186 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5707835" @default.
• W2772073186 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29204386" @default.
• W2772073186 hasPublicationYear "2017" @default.
• W2772073186 type Work @default.
• W2772073186 sameAs 2772073186 @default.
• W2772073186 citedByCount "2" @default.
• W2772073186 countsByYear W27720731862018 @default.
• W2772073186 countsByYear W27720731862021 @default.
• W2772073186 crossrefType "journal-article" @default.
• W2772073186 hasAuthorship W2772073186A5002253998 @default.
• W2772073186 hasAuthorship W2772073186A5045183822 @default.
• W2772073186 hasAuthorship W2772073186A5074609595 @default.
• W2772073186 hasAuthorship W2772073186A5076154362 @default.
• W2772073186 hasBestOaLocation W27720731861 @default.
• W2772073186 hasConcept C104317684 @default.
• W2772073186 hasConcept C124490489 @default.
• W2772073186 hasConcept C126322002 @default.
• W2772073186 hasConcept C135763542 @default.
• W2772073186 hasConcept C149737253 @default.
• W2772073186 hasConcept C16005928 @default.
• W2772073186 hasConcept C168007829 @default.
• W2772073186 hasConcept C179639408 @default.
• W2772073186 hasConcept C180754005 @default.
• W2772073186 hasConcept C2776677263 @default.
• W2772073186 hasConcept C2779105492 @default.
• W2772073186 hasConcept C54355233 @default.
• W2772073186 hasConcept C71924100 @default.
• W2772073186 hasConcept C76252995 @default.
• W2772073186 hasConcept C86803240 @default.
• W2772073186 hasConceptScore W2772073186C104317684 @default.
• W2772073186 hasConceptScore W2772073186C124490489 @default.
• W2772073186 hasConceptScore W2772073186C126322002 @default.
• W2772073186 hasConceptScore W2772073186C135763542 @default.
• W2772073186 hasConceptScore W2772073186C149737253 @default.
• W2772073186 hasConceptScore W2772073186C16005928 @default.
• W2772073186 hasConceptScore W2772073186C168007829 @default.
• W2772073186 hasConceptScore W2772073186C179639408 @default.
• W2772073186 hasConceptScore W2772073186C180754005 @default.
• W2772073186 hasConceptScore W2772073186C2776677263 @default.
• W2772073186 hasConceptScore W2772073186C2779105492 @default.
• W2772073186 hasConceptScore W2772073186C54355233 @default.
• W2772073186 hasConceptScore W2772073186C71924100 @default.
• W2772073186 hasConceptScore W2772073186C76252995 @default.
• W2772073186 hasConceptScore W2772073186C86803240 @default.
• W2772073186 hasLocation W27720731861 @default.
• W2772073186 hasLocation W27720731862 @default.
• W2772073186 hasLocation W27720731863 @default.
• W2772073186 hasLocation W27720731864 @default.
• W2772073186 hasLocation W27720731865 @default.
• W2772073186 hasOpenAccess W2772073186 @default.
• W2772073186 hasPrimaryLocation W27720731861 @default.
• W2772073186 hasRelatedWork W2114553125 @default.
• W2772073186 hasRelatedWork W2348970384 @default.
• W2772073186 hasRelatedWork W2351757521 @default.
• W2772073186 hasRelatedWork W2374660188 @default.
• W2772073186 hasRelatedWork W2383076329 @default.
• W2772073186 hasRelatedWork W2384893771 @default.
• W2772073186 hasRelatedWork W2397572595 @default.
• W2772073186 hasRelatedWork W2461703979 @default.
• W2772073186 hasRelatedWork W2772073186 @default.
• W2772073186 hasRelatedWork W3148031718 @default.

• next