FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2772079477> ?p ?o ?g. }

• W2772079477 endingPage "490" @default.
• W2772079477 startingPage "480" @default.
• W2772079477 abstract "A mosquito is known to precisely and easily insert its proboscis to the human skin by pressing down a labium and vibrating a fascicle bundle. Its advanced skin-piercing mechanisms indicate that skin resistance to the insertion of needle-like objects can be changed by the application of mechanophysical stimuli. Here, we characterize the effect of the application of mechanophysical stimuli on skin resistance to microneedle insertion to find clues for inserting a microneedle in a deep and precise fashion with low force. Microneedles with a diameter of 60–140 µm are inserted at a velocity of 0.1–2.0 mm/s to full-thickness porcine skins while either uniaxial/equibiaxial stretch of 0–20% or mechanical vibration at a frequency of 1 to 1000 Hz and an amplitude of 1–10 µm is applied to the skins as static or dynamic mechanophysical stimulus, respectively. The values of force and depth at two events of skin puncture and maximum penetration are measured to explore changes in skin resistance induced by the application of external stimuli. The static mechanophysical stimulus applied to the skin mainly affects the precision of microneedle insertion; the application of dynamic mechanophysical stimulus controls the value and deviation of skin resistance to microneedle insertion. The application of mechanophysical stimuli, inspired from a mosquito, therefore allows a microneedle to be deeply and easily inserted to the skin in a controlled way. The findings will have broad impacts on microneedle-mediated applications and lead to an in-depth understanding of skin biomechanics." @default.
• W2772079477 created "2017-12-22" @default.
• W2772079477 creator A5008301865 @default.
• W2772079477 creator A5050618975 @default.
• W2772079477 creator A5052194177 @default.
• W2772079477 creator A5063417001 @default.
• W2772079477 creator A5068257987 @default.
• W2772079477 creator A5080682087 @default.
• W2772079477 date "2018-02-01" @default.
• W2772079477 modified "2023-09-28" @default.
• W2772079477 title "Bioinspired microneedle insertion for deep and precise skin penetration with low force: Why the application of mechanophysical stimuli should be considered" @default.
• W2772079477 cites W1966936038 @default.
• W2772079477 cites W1970710265 @default.
• W2772079477 cites W1975853957 @default.
• W2772079477 cites W1981772845 @default.
• W2772079477 cites W1982974441 @default.
• W2772079477 cites W1987054766 @default.
• W2772079477 cites W1988871156 @default.
• W2772079477 cites W1996137682 @default.
• W2772079477 cites W1998488072 @default.
• W2772079477 cites W1999526290 @default.
• W2772079477 cites W2000574141 @default.
• W2772079477 cites W2003000923 @default.
• W2772079477 cites W2004143058 @default.
• W2772079477 cites W2014203632 @default.
• W2772079477 cites W2019019958 @default.
• W2772079477 cites W2021959041 @default.
• W2772079477 cites W2024888248 @default.
• W2772079477 cites W2041250960 @default.
• W2772079477 cites W2041658303 @default.
• W2772079477 cites W2044580452 @default.
• W2772079477 cites W2045172810 @default.
• W2772079477 cites W2047474960 @default.
• W2772079477 cites W2049428840 @default.
• W2772079477 cites W2051292995 @default.
• W2772079477 cites W2053684065 @default.
• W2772079477 cites W2054294261 @default.
• W2772079477 cites W2057930735 @default.
• W2772079477 cites W2063034638 @default.
• W2772079477 cites W2074770612 @default.
• W2772079477 cites W2075001207 @default.
• W2772079477 cites W2075674528 @default.
• W2772079477 cites W2078718040 @default.
• W2772079477 cites W2083490685 @default.
• W2772079477 cites W2084280576 @default.
• W2772079477 cites W2090415875 @default.
• W2772079477 cites W2097023289 @default.
• W2772079477 cites W2101946278 @default.
• W2772079477 cites W2109121052 @default.
• W2772079477 cites W2128851696 @default.
• W2772079477 cites W2137610248 @default.
• W2772079477 cites W2146558730 @default.
• W2772079477 cites W2148876857 @default.
• W2772079477 cites W2151363107 @default.
• W2772079477 cites W2152312983 @default.
• W2772079477 cites W2164152339 @default.
• W2772079477 cites W2165005041 @default.
• W2772079477 cites W2167462958 @default.
• W2772079477 cites W2167934753 @default.
• W2772079477 cites W2335972983 @default.
• W2772079477 cites W2339961086 @default.
• W2772079477 cites W2462019119 @default.
• W2772079477 cites W2606886292 @default.
• W2772079477 cites W4302358368 @default.
• W2772079477 doi "https://doi.org/10.1016/j.jmbbm.2017.12.006" @default.
• W2772079477 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29248845" @default.
• W2772079477 hasPublicationYear "2018" @default.
• W2772079477 type Work @default.
• W2772079477 sameAs 2772079477 @default.
• W2772079477 citedByCount "34" @default.
• W2772079477 countsByYear W27720794772018 @default.
• W2772079477 countsByYear W27720794772019 @default.
• W2772079477 countsByYear W27720794772020 @default.
• W2772079477 countsByYear W27720794772021 @default.
• W2772079477 countsByYear W27720794772022 @default.
• W2772079477 countsByYear W27720794772023 @default.
• W2772079477 crossrefType "journal-article" @default.
• W2772079477 hasAuthorship W2772079477A5008301865 @default.
• W2772079477 hasAuthorship W2772079477A5050618975 @default.
• W2772079477 hasAuthorship W2772079477A5052194177 @default.
• W2772079477 hasAuthorship W2772079477A5063417001 @default.
• W2772079477 hasAuthorship W2772079477A5068257987 @default.
• W2772079477 hasAuthorship W2772079477A5080682087 @default.
• W2772079477 hasConcept C127413603 @default.
• W2772079477 hasConcept C136229726 @default.
• W2772079477 hasConcept C175933922 @default.
• W2772079477 hasConcept C192562407 @default.
• W2772079477 hasConcept C2777459323 @default.
• W2772079477 hasConcept C42475967 @default.
• W2772079477 hasConcept C54355233 @default.
• W2772079477 hasConcept C71924100 @default.
• W2772079477 hasConcept C80107235 @default.
• W2772079477 hasConcept C86803240 @default.
• W2772079477 hasConceptScore W2772079477C127413603 @default.
• W2772079477 hasConceptScore W2772079477C136229726 @default.
• W2772079477 hasConceptScore W2772079477C175933922 @default.
• W2772079477 hasConceptScore W2772079477C192562407 @default.
• W2772079477 hasConceptScore W2772079477C2777459323 @default.

• next