Matches in SemOpenAlex for { <https://semopenalex.org/work/W2772337324> ?p ?o ?g. }
- W2772337324 abstract "Background: Since 1987 HIV scientists and activists have debated the optimal point to start antiretroviral treatment. Positions have varied between treating people with HIV as soon as they are diagnosed, based on biological, modelling and observational evidence, versus delaying treatment until points in disease progression at which clinical trial evidence has shown unequivocally that treatment is beneficial.Objectives: Examining the conduct and resolution of this debate may provide insight into how science works in practice. It also documents an important part of the history of the HIV epidemic.Method: We describe clinical trials, observational studies, models and various documents that have advanced the debate from 1987 to 2015.Results and conclusion: Evidence accumulated over the past decade, especially from randomised controlled clinical trials, has shown that immediate treatment both reduces the mortality and the risk of HIV transmission; it benefits both public health and the individual patient. By mid-2015, the debate was resolved in favour of immediate treatment." @default.
- W2772337324 created "2017-12-22" @default.
- W2772337324 creator A5007196445 @default.
- W2772337324 creator A5083719766 @default.
- W2772337324 date "2017-12-05" @default.
- W2772337324 modified "2023-09-28" @default.
- W2772337324 title "When to start antiretroviral treatment? A history and analysis of a scientific controversy" @default.
- W2772337324 cites W1497170016 @default.
- W2772337324 cites W1579322524 @default.
- W2772337324 cites W1764595352 @default.
- W2772337324 cites W1767940945 @default.
- W2772337324 cites W1970496489 @default.
- W2772337324 cites W1977900451 @default.
- W2772337324 cites W1985266931 @default.
- W2772337324 cites W1995380235 @default.
- W2772337324 cites W2050848142 @default.
- W2772337324 cites W2065865339 @default.
- W2772337324 cites W2068824261 @default.
- W2772337324 cites W2089695993 @default.
- W2772337324 cites W2100430786 @default.
- W2772337324 cites W2105213363 @default.
- W2772337324 cites W2115053153 @default.
- W2772337324 cites W2117128648 @default.
- W2772337324 cites W2122986037 @default.
- W2772337324 cites W2124995497 @default.
- W2772337324 cites W2127832030 @default.
- W2772337324 cites W2131295062 @default.
- W2772337324 cites W2131486930 @default.
- W2772337324 cites W2137091788 @default.
- W2772337324 cites W2143265231 @default.
- W2772337324 cites W2147865551 @default.
- W2772337324 cites W2152505869 @default.
- W2772337324 cites W2238552371 @default.
- W2772337324 cites W2287953481 @default.
- W2772337324 cites W2333399282 @default.
- W2772337324 cites W2403671454 @default.
- W2772337324 cites W2913770505 @default.
- W2772337324 cites W3146498960 @default.
- W2772337324 cites W2328905102 @default.
- W2772337324 doi "https://doi.org/10.4102/sajhivmed.v18i1.734" @default.
- W2772337324 hasPublicationYear "2017" @default.
- W2772337324 type Work @default.
- W2772337324 sameAs 2772337324 @default.
- W2772337324 citedByCount "3" @default.
- W2772337324 countsByYear W27723373242019 @default.
- W2772337324 countsByYear W27723373242021 @default.
- W2772337324 countsByYear W27723373242023 @default.
- W2772337324 crossrefType "journal-article" @default.
- W2772337324 hasAuthorship W2772337324A5007196445 @default.
- W2772337324 hasAuthorship W2772337324A5083719766 @default.
- W2772337324 hasBestOaLocation W27723373241 @default.
- W2772337324 hasConcept C111472728 @default.
- W2772337324 hasConcept C124056412 @default.
- W2772337324 hasConcept C138816342 @default.
- W2772337324 hasConcept C138885662 @default.
- W2772337324 hasConcept C141071460 @default.
- W2772337324 hasConcept C142462285 @default.
- W2772337324 hasConcept C142724271 @default.
- W2772337324 hasConcept C168563851 @default.
- W2772337324 hasConcept C177713679 @default.
- W2772337324 hasConcept C204787440 @default.
- W2772337324 hasConcept C23131810 @default.
- W2772337324 hasConcept C2779134260 @default.
- W2772337324 hasConcept C2779974597 @default.
- W2772337324 hasConcept C2993143319 @default.
- W2772337324 hasConcept C3013748606 @default.
- W2772337324 hasConcept C3019165603 @default.
- W2772337324 hasConcept C512399662 @default.
- W2772337324 hasConcept C535046627 @default.
- W2772337324 hasConcept C71924100 @default.
- W2772337324 hasConceptScore W2772337324C111472728 @default.
- W2772337324 hasConceptScore W2772337324C124056412 @default.
- W2772337324 hasConceptScore W2772337324C138816342 @default.
- W2772337324 hasConceptScore W2772337324C138885662 @default.
- W2772337324 hasConceptScore W2772337324C141071460 @default.
- W2772337324 hasConceptScore W2772337324C142462285 @default.
- W2772337324 hasConceptScore W2772337324C142724271 @default.
- W2772337324 hasConceptScore W2772337324C168563851 @default.
- W2772337324 hasConceptScore W2772337324C177713679 @default.
- W2772337324 hasConceptScore W2772337324C204787440 @default.
- W2772337324 hasConceptScore W2772337324C23131810 @default.
- W2772337324 hasConceptScore W2772337324C2779134260 @default.
- W2772337324 hasConceptScore W2772337324C2779974597 @default.
- W2772337324 hasConceptScore W2772337324C2993143319 @default.
- W2772337324 hasConceptScore W2772337324C3013748606 @default.
- W2772337324 hasConceptScore W2772337324C3019165603 @default.
- W2772337324 hasConceptScore W2772337324C512399662 @default.
- W2772337324 hasConceptScore W2772337324C535046627 @default.
- W2772337324 hasConceptScore W2772337324C71924100 @default.
- W2772337324 hasIssue "1" @default.
- W2772337324 hasLocation W27723373241 @default.
- W2772337324 hasOpenAccess W2772337324 @default.
- W2772337324 hasPrimaryLocation W27723373241 @default.
- W2772337324 hasRelatedWork W1764595352 @default.
- W2772337324 hasRelatedWork W1969139841 @default.
- W2772337324 hasRelatedWork W2054935322 @default.
- W2772337324 hasRelatedWork W2064986594 @default.
- W2772337324 hasRelatedWork W2081208367 @default.
- W2772337324 hasRelatedWork W2083535389 @default.
- W2772337324 hasRelatedWork W2087514416 @default.