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- W2772826058 abstract "Abstract Intraocular pressure (IOP) is a key clinical parameter in glaucoma management. However, despite the potential utility of daily measurements of IOP in the context of disease management, the necessary tools are currently lacking, and IOP is typically measured only a few times a year. Here we report on a microscale implantable sensor that could provide convenient, accurate, on-demand IOP monitoring in the home environment. When excited by broadband near-infrared (NIR) light from a tungsten bulb, the sensor’s optical cavity reflects a pressure-dependent resonance signature that can be converted to IOP. NIR light is minimally absorbed by tissue and is not perceived visually. The sensor’s nanodot-enhanced cavity allows for a 3–5 cm readout distance with an average accuracy of 0.29 mm Hg over the range of 0–40 mm Hg. Sensors were mounted onto intraocular lenses or silicone haptics and secured inside the anterior chamber in New Zealand white rabbits. Implanted sensors provided continuous in vivo tracking of short-term transient IOP elevations and provided continuous measurements of IOP for up to 4.5 months." @default.
- W2772826058 created "2017-12-22" @default.
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- W2772826058 date "2017-12-18" @default.
- W2772826058 modified "2023-10-18" @default.
- W2772826058 title "A microscale optical implant for continuous in vivo monitoring of intraocular pressure" @default.
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- W2772826058 doi "https://doi.org/10.1038/micronano.2017.57" @default.
- W2772826058 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6445001" @default.
- W2772826058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31057882" @default.
- W2772826058 hasPublicationYear "2017" @default.
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