FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2772838696> ?p ?o ?g. }

• W2772838696 endingPage "875" @default.
• W2772838696 startingPage "867" @default.
• W2772838696 abstract "BACKGROUND: Targeted temperature management (TTM) with therapeutic hypothermia is an integral component of postarrest care for survivors. However, recent randomized controlled trials (RCTs) have failed to demonstrate the benefit of TTM on clinical outcomes. We sought to determine if the pooled data from available RCTs support the use of prehospital and/or in-hospital TTM after cardiac arrest. METHODS: A comprehensive search of SCOPUS, Elsevier's abstract and citation database of peer-reviewed literature, from 1966 to November 2016 was performed using predefined criteria. Therapeutic hypothermia was defined as any strategy that aimed to cool post–cardiac arrest survivors to a temperature ≤34°C. Normothermia was temperature of ≥36°C. We compared mortality and neurologic outcomes in patients by categorizing the studies into 2 groups: (1) hypothermia versus normothermia and (2) prehospital hypothermia versus in-hospital hypothermia using standard meta-analytic methods. A random effects modeling was utilized to estimate comparative risk ratios (RR) and 95% confidence intervals (CIs). RESULTS: The hypothermia and normothermia strategies were compared in 5 RCTs with 1389 patients, whereas prehospital hypothermia and in-hospital hypothermia were compared in 6 RCTs with 3393 patients. We observed no difference in mortality (RR, 0.88; 95% CI, 0.73–1.05) or neurologic outcomes (RR, 1.26; 95% CI, 0.92–1.72) between the hypothermia and normothermia strategies. Similarly, no difference was observed in mortality (RR, 1.00; 95% CI, 0.97–1.03) or neurologic outcome (RR, 0.96; 95% CI, 0.85–1.08) between the prehospital hypothermia versus in-hospital hypothermia strategies. CONCLUSIONS: Our results suggest that TTM with therapeutic hypothermia may not improve mortality or neurologic outcomes in postarrest survivors. Using therapeutic hypothermia as a standard of care strategy of postarrest care in survivors may need to be reevaluated." @default.
• W2772838696 created "2017-12-22" @default.
• W2772838696 creator A5009457507 @default.
• W2772838696 creator A5030262630 @default.
• W2772838696 creator A5036729625 @default.
• W2772838696 creator A5056294557 @default.
• W2772838696 creator A5073142943 @default.
• W2772838696 creator A5075133520 @default.
• W2772838696 creator A5079746187 @default.
• W2772838696 date "2018-03-01" @default.
• W2772838696 modified "2023-10-17" @default.
• W2772838696 title "Targeted Temperature Management After Cardiac Arrest: Systematic Review and Meta-analyses" @default.
• W2772838696 cites W103126585 @default.
• W2772838696 cites W1480729244 @default.
• W2772838696 cites W1874700596 @default.
• W2772838696 cites W1983271145 @default.
• W2772838696 cites W1986215651 @default.
• W2772838696 cites W2005748286 @default.
• W2772838696 cites W2006496689 @default.
• W2772838696 cites W2033898528 @default.
• W2772838696 cites W2034229561 @default.
• W2772838696 cites W2038556396 @default.
• W2772838696 cites W2038693293 @default.
• W2772838696 cites W2049787783 @default.
• W2772838696 cites W2062642814 @default.
• W2772838696 cites W2071256185 @default.
• W2772838696 cites W2101602857 @default.
• W2772838696 cites W2104869294 @default.
• W2772838696 cites W2107092472 @default.
• W2772838696 cites W2107328434 @default.
• W2772838696 cites W2122968455 @default.
• W2772838696 cites W2123289930 @default.
• W2772838696 cites W2124645366 @default.
• W2772838696 cites W2126930838 @default.
• W2772838696 cites W2134852288 @default.
• W2772838696 cites W2141167900 @default.
• W2772838696 cites W2143457569 @default.
• W2772838696 cites W2145427448 @default.
• W2772838696 cites W2148405922 @default.
• W2772838696 cites W2150470528 @default.
• W2772838696 cites W2151217928 @default.
• W2772838696 cites W2154227981 @default.
• W2772838696 cites W2157347940 @default.
• W2772838696 cites W2157823046 @default.
• W2772838696 cites W2164130359 @default.
• W2772838696 cites W2171775058 @default.
• W2772838696 cites W2171886225 @default.
• W2772838696 cites W2180469576 @default.
• W2772838696 cites W2181372485 @default.
• W2772838696 cites W2211988058 @default.
• W2772838696 cites W2230641066 @default.
• W2772838696 cites W2281754568 @default.
• W2772838696 cites W2345811499 @default.
• W2772838696 cites W2490915042 @default.
• W2772838696 cites W2519185513 @default.
• W2772838696 cites W2556107335 @default.
• W2772838696 cites W3022903699 @default.
• W2772838696 doi "https://doi.org/10.1213/ane.0000000000002646" @default.
• W2772838696 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5820193" @default.
• W2772838696 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29239942" @default.
• W2772838696 hasPublicationYear "2018" @default.
• W2772838696 type Work @default.
• W2772838696 sameAs 2772838696 @default.
• W2772838696 citedByCount "32" @default.
• W2772838696 countsByYear W27728386962018 @default.
• W2772838696 countsByYear W27728386962019 @default.
• W2772838696 countsByYear W27728386962020 @default.
• W2772838696 countsByYear W27728386962021 @default.
• W2772838696 countsByYear W27728386962022 @default.
• W2772838696 countsByYear W27728386962023 @default.
• W2772838696 crossrefType "journal-article" @default.
• W2772838696 hasAuthorship W2772838696A5009457507 @default.
• W2772838696 hasAuthorship W2772838696A5030262630 @default.
• W2772838696 hasAuthorship W2772838696A5036729625 @default.
• W2772838696 hasAuthorship W2772838696A5056294557 @default.
• W2772838696 hasAuthorship W2772838696A5073142943 @default.
• W2772838696 hasAuthorship W2772838696A5075133520 @default.
• W2772838696 hasAuthorship W2772838696A5079746187 @default.
• W2772838696 hasBestOaLocation W27728386962 @default.
• W2772838696 hasConcept C126322002 @default.
• W2772838696 hasConcept C168563851 @default.
• W2772838696 hasConcept C2776296500 @default.
• W2772838696 hasConcept C2777055891 @default.
• W2772838696 hasConcept C2777390192 @default.
• W2772838696 hasConcept C2778165595 @default.
• W2772838696 hasConcept C2778619729 @default.
• W2772838696 hasConcept C42219234 @default.
• W2772838696 hasConcept C44249647 @default.
• W2772838696 hasConcept C71924100 @default.
• W2772838696 hasConcept C82789193 @default.
• W2772838696 hasConcept C95190672 @default.
• W2772838696 hasConceptScore W2772838696C126322002 @default.
• W2772838696 hasConceptScore W2772838696C168563851 @default.
• W2772838696 hasConceptScore W2772838696C2776296500 @default.
• W2772838696 hasConceptScore W2772838696C2777055891 @default.
• W2772838696 hasConceptScore W2772838696C2777390192 @default.
• W2772838696 hasConceptScore W2772838696C2778165595 @default.
• W2772838696 hasConceptScore W2772838696C2778619729 @default.

• next