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• W2772950492 abstract "Abstract Background An age‐related decrease in the number of osteogenic progenitor cells may compromise bone augmentation. Purpose Histomorphometrical assessment of age‐related new bone formation, following atrophic alveolar ridge reconstruction, using cancellous bone‐block allografts. Material and methods Ninety‐three consecutive patients (58 females and 35 males) were referred for implant‐supported restoration of 122 severe atrophic alveolar ridges. Alveolar ridge deficiency locations were classified as anterior maxilla ( n = 58), posterior maxilla ( n = 32), and posterior mandible ( n = 32). A bony deficiency of at least 3 mm horizontally and up to 3 mm vertically according to computerized tomography (CT) in the posterior mandible and anterior maxilla, served as inclusion criteria. In the posterior maxilla, a residual alveolar ridge up to 4 mm vertically according to CT served as inclusion criteria. Augmentation was performed by the use of cancellous bone‐block allografts. Bone biopsies (9‐month posterior maxilla, 4 months anterior maxilla and posterior mandible) of young (≤40 years) versus older (>40 years) patients were histomorphometrically evaluated. Results In the posterior maxilla, no statistically significant histomorphometric differences were noted. While at the anterior maxilla and posterior mandible, statistically significant more newly formed bone was found in young versus older individuals, respectively (38.6% vs 19.8%, P = 0.04 and 69% vs 31%, P = .05). Conclusion New bone formation following residual alveolar ridge bone grafting is age‐related. Longer bone consolidation and healing time may be recommended for older individuals." @default.
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• W2772950492 date "2017-12-01" @default.
• W2772950492 modified "2023-10-16" @default.
• W2772950492 title "Age-related new bone formation following the use of cancellous bone-block allografts for reconstruction of atrophic alveolar ridges" @default.
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• W2772950492 doi "https://doi.org/10.1111/cid.12560" @default.
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