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- W2772997310 abstract "There are strong evidences that common mitochondrial DNA (mtDNA) haplogroups may influence the pathogenesis of cardiovascular diseases (CVDs). In this matched case-control study, we investigate the association between mtDNA haplogroups and two CVDs, myocardial infarction (MI) and stroke, and classical cardiovascular risk factors. Data obtained show that haplogroup H constitute a susceptibility risk factor for MI (p = 0.001; OR = 2.379, 95% CI [1.440–3.990]). Otherwise, our data also suggest a beneficial role of haplogroup J against hypertension (p = 0.019; OR = 0.348, 95% CI [0.144–0.840]). These results may provide some guidance for predicting the genetic risk of these diseases in different human populations through the differences in energy efficiency between haplogroups." @default.
- W2772997310 created "2017-12-22" @default.
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- W2772997310 date "2019-01-01" @default.
- W2772997310 modified "2023-10-12" @default.
- W2772997310 title "Involvement of mitochondrial haplogroups in myocardial infarction and stroke: A case-control study in Castile and Leon (Spain) population" @default.
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- W2772997310 doi "https://doi.org/10.1016/j.mito.2017.12.004" @default.
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