FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2773181066> ?p ?o ?g. }

• W2773181066 endingPage "85" @default.
• W2773181066 startingPage "85" @default.
• W2773181066 abstract "Ascorbic acid has been reported to have an adipogenic effect on 3T3-L1 preadipocytes, while evidence also suggests that ascorbic acid reduces body weight in humans. In this study, we tested the effects of ascorbic acid on adipogenesis and the balance of lipid accumulation in ovariectomized rats, in addition to long-term culture of differentiated 3T3-L1 adipocytes.Murine 3T3-L1 fibroblasts and ovariectomized rats were treated with ascorbic acid at various time points. In vitro adipogenesis was analyzed by Oil Red O staining, and in vivo body fat was measured by a body composition analyzer using nuclear magnetic resonance.When ascorbic acid was applied during an early time point in 3T3-L1 preadipocyte differentiation and after bilateral ovariectomy (OVX) in rats, adipogenesis and fat mass gain significantly increased, respectively. However, lipid accumulation in well-differentiated 3T3-L1 adipocytes showed a significant reduction when ascorbic acid was applied after differentiation (10 days after induction). Also, oral ascorbic acid administration 4 weeks after OVX in rats significantly reduced both body weight and subcutaneous fat layer. In comparison to the results of ascorbic acid, which is a well-known cofactor for an enzyme of collagen synthesis, and the antioxidant ramalin, a potent antioxidant but not a cofactor, showed only a lipolytic effect in well-differentiated 3T3-L1 adipocytes, not an adipogenic effect.Taking these results into account, we concluded that ascorbic acid has both an adipogenic effect as a cofactor of an enzymatic process and a lipolytic effect as an antioxidant." @default.
• W2773181066 created "2017-12-22" @default.
• W2773181066 creator A5000436607 @default.
• W2773181066 creator A5034176785 @default.
• W2773181066 creator A5041898048 @default.
• W2773181066 creator A5075466654 @default.
• W2773181066 creator A5082422712 @default.
• W2773181066 creator A5082573289 @default.
• W2773181066 date "2018-01-01" @default.
• W2773181066 modified "2023-10-18" @default.
• W2773181066 title "Adipogenic and Lipolytic Effects of Ascorbic Acid in Ovariectomized Rats" @default.
• W2773181066 cites W1508604676 @default.
• W2773181066 cites W1542645650 @default.
• W2773181066 cites W1918688335 @default.
• W2773181066 cites W1967448842 @default.
• W2773181066 cites W1969836283 @default.
• W2773181066 cites W1970499787 @default.
• W2773181066 cites W1977770985 @default.
• W2773181066 cites W1990223276 @default.
• W2773181066 cites W1994155619 @default.
• W2773181066 cites W2010163856 @default.
• W2773181066 cites W2013646480 @default.
• W2773181066 cites W2030068752 @default.
• W2773181066 cites W2039354575 @default.
• W2773181066 cites W2048614135 @default.
• W2773181066 cites W2056763289 @default.
• W2773181066 cites W2072095657 @default.
• W2773181066 cites W2078939137 @default.
• W2773181066 cites W2084063366 @default.
• W2773181066 cites W2097036103 @default.
• W2773181066 cites W2100577464 @default.
• W2773181066 cites W2101001040 @default.
• W2773181066 cites W2119754755 @default.
• W2773181066 cites W2482490599 @default.
• W2773181066 cites W2487403806 @default.
• W2773181066 cites W2521747054 @default.
• W2773181066 doi "https://doi.org/10.3349/ymj.2018.59.1.85" @default.
• W2773181066 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5725369" @default.
• W2773181066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29214781" @default.
• W2773181066 hasPublicationYear "2018" @default.
• W2773181066 type Work @default.
• W2773181066 sameAs 2773181066 @default.
• W2773181066 citedByCount "7" @default.
• W2773181066 countsByYear W27731810662018 @default.
• W2773181066 countsByYear W27731810662020 @default.
• W2773181066 countsByYear W27731810662021 @default.
• W2773181066 countsByYear W27731810662022 @default.
• W2773181066 crossrefType "journal-article" @default.
• W2773181066 hasAuthorship W2773181066A5000436607 @default.
• W2773181066 hasAuthorship W2773181066A5034176785 @default.
• W2773181066 hasAuthorship W2773181066A5041898048 @default.
• W2773181066 hasAuthorship W2773181066A5075466654 @default.
• W2773181066 hasAuthorship W2773181066A5082422712 @default.
• W2773181066 hasAuthorship W2773181066A5082573289 @default.
• W2773181066 hasBestOaLocation W27731810661 @default.
• W2773181066 hasConcept C122927707 @default.
• W2773181066 hasConcept C126322002 @default.
• W2773181066 hasConcept C134018914 @default.
• W2773181066 hasConcept C171089720 @default.
• W2773181066 hasConcept C185592680 @default.
• W2773181066 hasConcept C2778004101 @default.
• W2773181066 hasConcept C2986274086 @default.
• W2773181066 hasConcept C31903555 @default.
• W2773181066 hasConcept C55493867 @default.
• W2773181066 hasConcept C71315377 @default.
• W2773181066 hasConcept C71924100 @default.
• W2773181066 hasConcept C8264082 @default.
• W2773181066 hasConcept C86803240 @default.
• W2773181066 hasConceptScore W2773181066C122927707 @default.
• W2773181066 hasConceptScore W2773181066C126322002 @default.
• W2773181066 hasConceptScore W2773181066C134018914 @default.
• W2773181066 hasConceptScore W2773181066C171089720 @default.
• W2773181066 hasConceptScore W2773181066C185592680 @default.
• W2773181066 hasConceptScore W2773181066C2778004101 @default.
• W2773181066 hasConceptScore W2773181066C2986274086 @default.
• W2773181066 hasConceptScore W2773181066C31903555 @default.
• W2773181066 hasConceptScore W2773181066C55493867 @default.
• W2773181066 hasConceptScore W2773181066C71315377 @default.
• W2773181066 hasConceptScore W2773181066C71924100 @default.
• W2773181066 hasConceptScore W2773181066C8264082 @default.
• W2773181066 hasConceptScore W2773181066C86803240 @default.
• W2773181066 hasFunder F4320321373 @default.
• W2773181066 hasFunder F4320322120 @default.
• W2773181066 hasIssue "1" @default.
• W2773181066 hasLocation W27731810661 @default.
• W2773181066 hasLocation W27731810662 @default.
• W2773181066 hasLocation W27731810663 @default.
• W2773181066 hasLocation W27731810664 @default.
• W2773181066 hasOpenAccess W2773181066 @default.
• W2773181066 hasPrimaryLocation W27731810661 @default.
• W2773181066 hasRelatedWork W2070612534 @default.
• W2773181066 hasRelatedWork W2084245009 @default.
• W2773181066 hasRelatedWork W2093572014 @default.
• W2773181066 hasRelatedWork W2361999276 @default.
• W2773181066 hasRelatedWork W2385939269 @default.
• W2773181066 hasRelatedWork W2386420363 @default.
• W2773181066 hasRelatedWork W2393570286 @default.
• W2773181066 hasRelatedWork W2398068415 @default.

• next