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- W277333712 abstract "Publisher Summary This chapter discusses the physiological genetics of mouse. It reviews the effect of mutations in different organ systems of the mouse that include skeleton, integument, nervous system, pigment-forming system, blood, and developmental systems of the embryo. Mutations is discussed where an effect on enzyme systems can be demonstrated, such as those affecting pigmentation. Hemoglobin synthesis is shown to be disturbed in different hematopoietic tissues and in different phases of development by the action of mutational changes with far-reaching effects. One syndrome of abnormalities is discussed that is shown to have arisen as a result of the mutational effect on a hormone. The developmental analysis of some abnormalities of the nervous system demonstrates how the original effect of a mutation may show no direct relation to the eventual symptoms. The analysis of other mutations reveals that their effects are due to the changed rates of growth and differentiation of certain tissues." @default.
- W277333712 created "2016-06-24" @default.
- W277333712 creator A5070785867 @default.
- W277333712 date "1951-01-01" @default.
- W277333712 modified "2023-09-26" @default.
- W277333712 title "Physiological Genetics of the Mouse" @default.
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- W277333712 doi "https://doi.org/10.1016/s0065-2660(08)60230-8" @default.
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