FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2773659596> ?p ?o ?g. }

• W2773659596 endingPage "489" @default.
• W2773659596 startingPage "480" @default.
• W2773659596 abstract "Long-acting neuraxial opioids provide excellent analgesia after surgery, but are associated with higher rates of postoperative nausea and vomiting. Dexamethasone effectively prevents postoperative nausea and vomiting after general anaesthesia, but its value in patients receiving long-acting neuraxial opioids is undetermined. Therefore, the objective of this meta-analysis was to assess the prophylactic anti-emetic efficacy of intravenous (i.v.) dexamethasone in this population. The study methodology followed the PRISMA statement guidelines. The primary outcome was the need for rescue anti-emetics during the first 24 postoperative hours, analysed according to the dose of dexamethasone (low-dose 2.5-5.0 mg; intermediate dose 6.0-10.0 mg), timing of administration (beginning or end of surgery) and route of long-acting opioid administration (intrathecal or epidural). Additionally, the rates of complications (restlessness, infection, hyperglycaemia) were sought. Thirteen trials were identified, representing a total of 1111 patients. When compared with placebo, intravenous dexamethasone reduced the need for rescue anti-emetics (risk ratio (95%CI) 0.44 (0.35-0.56); I2 = 43%; p < 0.00001; quality of GRADE evidence: moderate), without differences between dexamethasone doses (p for sub-group difference = 0.67), timing of administration (p for sub-group difference = 0.32) or route of long-acting opioid (p for sub-group difference = 0.10). No patients developed infection or restlessness among trials that sought these complications. No trial measured blood glucose levels. In conclusion, there is enough evidence to state that intravenous dexamethasone provides effective anti-emetic prophylaxis during the first 24 postoperative hours in patients who receive long-acting neuraxial opioids." @default.
• W2773659596 created "2017-12-22" @default.
• W2773659596 creator A5007702535 @default.
• W2773659596 creator A5017653508 @default.
• W2773659596 creator A5039115391 @default.
• W2773659596 creator A5082596627 @default.
• W2773659596 date "2017-12-11" @default.
• W2773659596 modified "2023-10-17" @default.
• W2773659596 title "Intravenous dexamethasone for prophylaxis of postoperative nausea and vomiting after administration of long‐acting neuraxial opioids: a systematic review and meta‐analysis" @default.
• W2773659596 cites W1978777348 @default.
• W2773659596 cites W1978871651 @default.
• W2773659596 cites W2014772207 @default.
• W2773659596 cites W2033585778 @default.
• W2773659596 cites W2033809002 @default.
• W2773659596 cites W2045893158 @default.
• W2773659596 cites W2057250652 @default.
• W2773659596 cites W2057450456 @default.
• W2773659596 cites W2078010750 @default.
• W2773659596 cites W2096740387 @default.
• W2773659596 cites W2098923148 @default.
• W2773659596 cites W2101977849 @default.
• W2773659596 cites W2109307601 @default.
• W2773659596 cites W2113009866 @default.
• W2773659596 cites W2126365855 @default.
• W2773659596 cites W2126930838 @default.
• W2773659596 cites W2129285275 @default.
• W2773659596 cites W2135400982 @default.
• W2773659596 cites W2143608063 @default.
• W2773659596 cites W2146491431 @default.
• W2773659596 cites W2157010033 @default.
• W2773659596 cites W2169205464 @default.
• W2773659596 cites W2170209256 @default.
• W2773659596 cites W2189448871 @default.
• W2773659596 cites W2196753110 @default.
• W2773659596 cites W2206340279 @default.
• W2773659596 cites W2312804035 @default.
• W2773659596 cites W2331796246 @default.
• W2773659596 cites W2497760421 @default.
• W2773659596 cites W2507445776 @default.
• W2773659596 cites W2529597016 @default.
• W2773659596 cites W2546985081 @default.
• W2773659596 cites W2568964326 @default.
• W2773659596 cites W2587800844 @default.
• W2773659596 cites W4251081008 @default.
• W2773659596 doi "https://doi.org/10.1111/anae.14166" @default.
• W2773659596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29226971" @default.
• W2773659596 hasPublicationYear "2017" @default.
• W2773659596 type Work @default.
• W2773659596 sameAs 2773659596 @default.
• W2773659596 citedByCount "25" @default.
• W2773659596 countsByYear W27736595962019 @default.
• W2773659596 countsByYear W27736595962020 @default.
• W2773659596 countsByYear W27736595962021 @default.
• W2773659596 countsByYear W27736595962022 @default.
• W2773659596 countsByYear W27736595962023 @default.
• W2773659596 crossrefType "journal-article" @default.
• W2773659596 hasAuthorship W2773659596A5007702535 @default.
• W2773659596 hasAuthorship W2773659596A5017653508 @default.
• W2773659596 hasAuthorship W2773659596A5039115391 @default.
• W2773659596 hasAuthorship W2773659596A5082596627 @default.
• W2773659596 hasBestOaLocation W27736595961 @default.
• W2773659596 hasConcept C126322002 @default.
• W2773659596 hasConcept C142724271 @default.
• W2773659596 hasConcept C170493617 @default.
• W2773659596 hasConcept C204787440 @default.
• W2773659596 hasConcept C27081682 @default.
• W2773659596 hasConcept C2776983577 @default.
• W2773659596 hasConcept C2777297131 @default.
• W2773659596 hasConcept C2780401358 @default.
• W2773659596 hasConcept C2780580376 @default.
• W2773659596 hasConcept C2780852908 @default.
• W2773659596 hasConcept C2781063702 @default.
• W2773659596 hasConcept C2908647359 @default.
• W2773659596 hasConcept C42219234 @default.
• W2773659596 hasConcept C71924100 @default.
• W2773659596 hasConcept C99454951 @default.
• W2773659596 hasConceptScore W2773659596C126322002 @default.
• W2773659596 hasConceptScore W2773659596C142724271 @default.
• W2773659596 hasConceptScore W2773659596C170493617 @default.
• W2773659596 hasConceptScore W2773659596C204787440 @default.
• W2773659596 hasConceptScore W2773659596C27081682 @default.
• W2773659596 hasConceptScore W2773659596C2776983577 @default.
• W2773659596 hasConceptScore W2773659596C2777297131 @default.
• W2773659596 hasConceptScore W2773659596C2780401358 @default.
• W2773659596 hasConceptScore W2773659596C2780580376 @default.
• W2773659596 hasConceptScore W2773659596C2780852908 @default.
• W2773659596 hasConceptScore W2773659596C2781063702 @default.
• W2773659596 hasConceptScore W2773659596C2908647359 @default.
• W2773659596 hasConceptScore W2773659596C42219234 @default.
• W2773659596 hasConceptScore W2773659596C71924100 @default.
• W2773659596 hasConceptScore W2773659596C99454951 @default.
• W2773659596 hasFunder F4320323833 @default.
• W2773659596 hasIssue "4" @default.
• W2773659596 hasLocation W27736595961 @default.
• W2773659596 hasLocation W27736595962 @default.
• W2773659596 hasOpenAccess W2773659596 @default.
• W2773659596 hasPrimaryLocation W27736595961 @default.
• W2773659596 hasRelatedWork W1593472362 @default.

• next