FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2773666809> ?p ?o ?g. }

• W2773666809 abstract "Adverse Reaction to Metal Debris (ARMD) is still a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. ARMD consists of a wide range of alterations in periprosthetic tissues, most important of which are metallosis, inflammation, pseudotumors and necrosis. Studies investigating histopathological findings and their association to implant wear or indirect measures of wear have yielded inconsistent results. Therefore, we aimed to investigate bearing surface wear volume, whole blood and synovial fluid metal ion concentrations, histopathological findings in periprosthetic tissues and their associations. Seventy-eight patients with 85 hips revised for ARMD were included in the study. Prior to revision surgery, all patients had whole blood chromium and cobalt ion levels assessed. In revision surgery, a synovial fluid sample was taken and analyzed for chromium and cobalt. Periprosthetic tissue samples were taken and analyzed for histopathological findings. Explanted implants were analyzed for bearing wear volume of both acetabular cup and femoral head components. Volumetric wear of the failed components was highly variable. The total wear volume of the head and cup had a strong correlation with whole blood chromium and cobalt ion concentrations (Cr: ρ = 0.80, p < 0.001 and Co: ρ = 0.84, p < 0.001) and a bit weaker correlation with fluid chromium and cobalt ion concentrations (Cr: ρ = 0.50, p < 0.01 and Co: ρ = 0.41, p = 0.027). Most tissues displayed only low-to-moderate amounts of macrophages and lymphocytes. Total wear volume correlated with macrophage sheet thickness (ρ = 0.25, p = 0.020) and necrosis (ρ = 0.35, p < 0.01). Whole blood chromium and cobalt ion concentrations had similar correlations. Lymphocyte cuff thickness did not correlate with either total wear volume or whole blood metal ion concentrations, but correlated with the grade of necrosis. Bearing wear volume correlated with blood metal ion levels and the degree of necrosis and macrophage infiltration in periprosthetic tissues suggesting a dose-response relationship. Whole blood metal ion levels are a useful tool for clinician to estimate bearing wear and subsequent tissue response." @default.
• W2773666809 created "2017-12-22" @default.
• W2773666809 creator A5011190139 @default.
• W2773666809 creator A5012311362 @default.
• W2773666809 creator A5047486281 @default.
• W2773666809 creator A5051797910 @default.
• W2773666809 creator A5062676542 @default.
• W2773666809 creator A5089187769 @default.
• W2773666809 creator A5089284723 @default.
• W2773666809 date "2017-12-01" @default.
• W2773666809 modified "2023-09-25" @default.
• W2773666809 title "Analysis of bearing wear, whole blood and synovial fluid metal ion concentrations and histopathological findings in patients with failed ASR hip resurfacings" @default.
• W2773666809 cites W1939602621 @default.
• W2773666809 cites W1970848201 @default.
• W2773666809 cites W1973410706 @default.
• W2773666809 cites W1983390285 @default.
• W2773666809 cites W1993086045 @default.
• W2773666809 cites W2003699682 @default.
• W2773666809 cites W2010651579 @default.
• W2773666809 cites W2027307269 @default.
• W2773666809 cites W2029704408 @default.
• W2773666809 cites W2033965870 @default.
• W2773666809 cites W2035272671 @default.
• W2773666809 cites W2040754785 @default.
• W2773666809 cites W2045167373 @default.
• W2773666809 cites W2046637170 @default.
• W2773666809 cites W2046698700 @default.
• W2773666809 cites W2060258231 @default.
• W2773666809 cites W2081964861 @default.
• W2773666809 cites W2088113721 @default.
• W2773666809 cites W2090799024 @default.
• W2773666809 cites W2095997731 @default.
• W2773666809 cites W2103262122 @default.
• W2773666809 cites W2105188510 @default.
• W2773666809 cites W2118133665 @default.
• W2773666809 cites W2131215494 @default.
• W2773666809 cites W2132045171 @default.
• W2773666809 cites W2141382736 @default.
• W2773666809 cites W2143332222 @default.
• W2773666809 cites W2156880804 @default.
• W2773666809 cites W2171201114 @default.
• W2773666809 cites W2211091206 @default.
• W2773666809 cites W2247534830 @default.
• W2773666809 cites W2254721406 @default.
• W2773666809 cites W2264992901 @default.
• W2773666809 cites W2279414027 @default.
• W2773666809 cites W2282502185 @default.
• W2773666809 cites W2346866670 @default.
• W2773666809 cites W2403077834 @default.
• W2773666809 cites W2406892609 @default.
• W2773666809 cites W2550407298 @default.
• W2773666809 cites W336810645 @default.
• W2773666809 doi "https://doi.org/10.1186/s12891-017-1894-5" @default.
• W2773666809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5725985" @default.
• W2773666809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29228956" @default.
• W2773666809 hasPublicationYear "2017" @default.
• W2773666809 type Work @default.
• W2773666809 sameAs 2773666809 @default.
• W2773666809 citedByCount "13" @default.
• W2773666809 countsByYear W27736668092018 @default.
• W2773666809 countsByYear W27736668092019 @default.
• W2773666809 countsByYear W27736668092020 @default.
• W2773666809 countsByYear W27736668092021 @default.
• W2773666809 countsByYear W27736668092023 @default.
• W2773666809 crossrefType "journal-article" @default.
• W2773666809 hasAuthorship W2773666809A5011190139 @default.
• W2773666809 hasAuthorship W2773666809A5012311362 @default.
• W2773666809 hasAuthorship W2773666809A5047486281 @default.
• W2773666809 hasAuthorship W2773666809A5051797910 @default.
• W2773666809 hasAuthorship W2773666809A5062676542 @default.
• W2773666809 hasAuthorship W2773666809A5089187769 @default.
• W2773666809 hasAuthorship W2773666809A5089284723 @default.
• W2773666809 hasBestOaLocation W27736668091 @default.
• W2773666809 hasConcept C141071460 @default.
• W2773666809 hasConcept C142724271 @default.
• W2773666809 hasConcept C159985019 @default.
• W2773666809 hasConcept C1621761 @default.
• W2773666809 hasConcept C184608416 @default.
• W2773666809 hasConcept C187435122 @default.
• W2773666809 hasConcept C191897082 @default.
• W2773666809 hasConcept C192562407 @default.
• W2773666809 hasConcept C204787440 @default.
• W2773666809 hasConcept C2776164576 @default.
• W2773666809 hasConcept C2776268809 @default.
• W2773666809 hasConcept C2778120723 @default.
• W2773666809 hasConcept C2778336525 @default.
• W2773666809 hasConcept C2779726759 @default.
• W2773666809 hasConcept C511782168 @default.
• W2773666809 hasConcept C71924100 @default.
• W2773666809 hasConceptScore W2773666809C141071460 @default.
• W2773666809 hasConceptScore W2773666809C142724271 @default.
• W2773666809 hasConceptScore W2773666809C159985019 @default.
• W2773666809 hasConceptScore W2773666809C1621761 @default.
• W2773666809 hasConceptScore W2773666809C184608416 @default.
• W2773666809 hasConceptScore W2773666809C187435122 @default.
• W2773666809 hasConceptScore W2773666809C191897082 @default.
• W2773666809 hasConceptScore W2773666809C192562407 @default.
• W2773666809 hasConceptScore W2773666809C204787440 @default.
• W2773666809 hasConceptScore W2773666809C2776164576 @default.
• W2773666809 hasConceptScore W2773666809C2776268809 @default.

• next