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- W2773984989 endingPage "e0189788" @default.
- W2773984989 startingPage "e0189788" @default.
- W2773984989 abstract "In Arabidopsis, the F-box HAWAIIAN SKIRT (HWS) protein is important for organ growth. Loss of function of HWS exhibits pleiotropic phenotypes including sepal fusion. To dissect the HWS role, we EMS-mutagenized hws-1 seeds and screened for mutations that suppress hws-1 associated phenotypes. We identified shs-2 and shs-3 (suppressor of hws-2 and 3) mutants in which the sepal fusion phenotype of hws-1 was suppressed. shs-2 and shs-3 (renamed hst-23/hws-1 and hst-24/hws-1) carry transition mutations that result in premature terminations in the plant homolog of Exportin-5 HASTY (HST), known to be important in miRNA biogenesis, function and transport. Genetic crosses between hws-1 and mutant lines for genes in the miRNA pathway also suppress the phenotypes associated with HWS loss of function, corroborating epistatic relations between the miRNA pathway genes and HWS. In agreement with these data, accumulation of miRNA is modified in HWS loss or gain of function mutants. Our data propose HWS as a new player in the miRNA pathway, important for plant growth." @default.
- W2773984989 created "2017-12-22" @default.
- W2773984989 creator A5004168613 @default.
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- W2773984989 creator A5076213465 @default.
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- W2773984989 date "2017-12-15" @default.
- W2773984989 modified "2023-10-16" @default.
- W2773984989 title "The Arabidopsis thaliana F-box gene HAWAIIAN SKIRT is a new player in the microRNA pathway" @default.
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- W2773984989 doi "https://doi.org/10.1371/journal.pone.0189788" @default.
- W2773984989 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5731758" @default.
- W2773984989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29244865" @default.
- W2773984989 hasPublicationYear "2017" @default.
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