FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2774004935> ?p ?o ?g. }

• W2774004935 abstract "Within several weeks of use as coronary artery bypass grafts (CABG), saphenous veins (SV) exhibit significant intimal hyperplasia (IH). IH predisposes vessels to thrombosis and atherosclerosis, the two major modes of vein graft failure. The fact that SV do not develop significant IH in their native venous environment coupled with the rapidity with which they develop IH following grafting into the arterial circulation suggests that factors associated with the isolation and preparation of SV and/or differences between the venous and arterial environments contribute to disease progression. There is strong evidence suggesting that mechanical trauma associated with traditional techniques of SV preparation can significantly damage the vessel and might potentially reduce graft patency though modern surgical techniques reduces these injuries. In contrast, it seems possible that modern surgical technique, specifically endoscopic vein harvest, might introduce other mechanical trauma that could subtly injure the vein and perhaps contribute to the reduced patency observed in veins harvested using endoscopic techniques. Aspects of the arterial mechanical environment influence remodeling of SV grafted into the arterial circulation. Increased pressure likely leads to thickening of the medial wall but its role in IH is less clear. Changes in fluid flow, including increased average wall shear stress, may reduce IH while disturbed flow likely increase IH. Nonmechanical stimuli, such as exposure to arterial levels of oxygen, may also have a significant but not widely recognized role in IH. Several potentially promising approaches to alter the mechanical environment to improve graft patency are including extravascular supports or altered graft geometries are covered." @default.
• W2774004935 created "2017-12-22" @default.
• W2774004935 creator A5003840010 @default.
• W2774004935 creator A5015212263 @default.
• W2774004935 creator A5038161400 @default.
• W2774004935 creator A5049967065 @default.
• W2774004935 date "2018-01-12" @default.
• W2774004935 modified "2023-10-13" @default.
• W2774004935 title "Biomechanics and Mechanobiology of Saphenous Vein Grafts" @default.
• W2774004935 cites W1566068424 @default.
• W2774004935 cites W1779818251 @default.
• W2774004935 cites W192738711 @default.
• W2774004935 cites W1936770188 @default.
• W2774004935 cites W1964549548 @default.
• W2774004935 cites W1968460690 @default.
• W2774004935 cites W1968938828 @default.
• W2774004935 cites W1970265550 @default.
• W2774004935 cites W1970614887 @default.
• W2774004935 cites W1971483230 @default.
• W2774004935 cites W1971959573 @default.
• W2774004935 cites W1972161075 @default.
• W2774004935 cites W1976512255 @default.
• W2774004935 cites W1977794018 @default.
• W2774004935 cites W1979038946 @default.
• W2774004935 cites W1980011916 @default.
• W2774004935 cites W1980846857 @default.
• W2774004935 cites W1981822404 @default.
• W2774004935 cites W1982978078 @default.
• W2774004935 cites W1983270966 @default.
• W2774004935 cites W1985150597 @default.
• W2774004935 cites W1985529964 @default.
• W2774004935 cites W1986070439 @default.
• W2774004935 cites W1986882801 @default.
• W2774004935 cites W1988051059 @default.
• W2774004935 cites W1989334874 @default.
• W2774004935 cites W1991338473 @default.
• W2774004935 cites W1991568785 @default.
• W2774004935 cites W1991578528 @default.
• W2774004935 cites W1996606936 @default.
• W2774004935 cites W1998008462 @default.
• W2774004935 cites W1999083451 @default.
• W2774004935 cites W1999959517 @default.
• W2774004935 cites W2000958015 @default.
• W2774004935 cites W2001822903 @default.
• W2774004935 cites W2002957986 @default.
• W2774004935 cites W2004899731 @default.
• W2774004935 cites W2005381611 @default.
• W2774004935 cites W2005382430 @default.
• W2774004935 cites W2007006539 @default.
• W2774004935 cites W2007120458 @default.
• W2774004935 cites W2008691173 @default.
• W2774004935 cites W2009883791 @default.
• W2774004935 cites W2010888269 @default.
• W2774004935 cites W2012517770 @default.
• W2774004935 cites W2013620136 @default.
• W2774004935 cites W2014073237 @default.
• W2774004935 cites W2015287913 @default.
• W2774004935 cites W2015299128 @default.
• W2774004935 cites W2015919373 @default.
• W2774004935 cites W2016156567 @default.
• W2774004935 cites W2016165812 @default.
• W2774004935 cites W2016218345 @default.
• W2774004935 cites W2016929068 @default.
• W2774004935 cites W2017625969 @default.
• W2774004935 cites W2018127459 @default.
• W2774004935 cites W2018160430 @default.
• W2774004935 cites W2021086283 @default.
• W2774004935 cites W2021126566 @default.
• W2774004935 cites W2021823221 @default.
• W2774004935 cites W2022960456 @default.
• W2774004935 cites W2023855479 @default.
• W2774004935 cites W2024141041 @default.
• W2774004935 cites W2024450698 @default.
• W2774004935 cites W2026980150 @default.
• W2774004935 cites W2027311581 @default.
• W2774004935 cites W2028531936 @default.
• W2774004935 cites W2028923896 @default.
• W2774004935 cites W2030354697 @default.
• W2774004935 cites W2032399923 @default.
• W2774004935 cites W2032499978 @default.
• W2774004935 cites W2032647105 @default.
• W2774004935 cites W2034115658 @default.
• W2774004935 cites W2036038570 @default.
• W2774004935 cites W2036246880 @default.
• W2774004935 cites W2037152866 @default.
• W2774004935 cites W2038600384 @default.
• W2774004935 cites W2039089471 @default.
• W2774004935 cites W2039395289 @default.
• W2774004935 cites W2040676050 @default.
• W2774004935 cites W2042349233 @default.
• W2774004935 cites W2042349974 @default.
• W2774004935 cites W2044302249 @default.
• W2774004935 cites W2044768795 @default.
• W2774004935 cites W2048179019 @default.
• W2774004935 cites W2048784971 @default.
• W2774004935 cites W2050902833 @default.
• W2774004935 cites W2054114699 @default.
• W2774004935 cites W2059013218 @default.
• W2774004935 cites W2059969675 @default.
• W2774004935 cites W2060683523 @default.

• next