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- W2774403566 abstract "Abstract The ability of bacteria to exist as a population of self-replicating forms with defective or entirely missing cell wall (L-forms) is an adaptive mechanism for their survival and reproduction under unfavorable conditions. Bacterial mother-to-fetus transfer is a universal phenomenon in the animal kingdom. However, data about vertical transfer of L bacterial forms are extremely scarce. Bacille Calmette-Guérin is an attenuated strain of M. bovis and the only licensed vaccine used for tuberculosis prevention. We already have shown that filterable L-forms of BCG exist freely in the vaccine and are able to reproduce and to form colonies. The present study was focused on the placental microbiome in the context of mother’s BCG vaccination. Here we report an isolation of filterable mycobacterial L-form cultures from gestational tissues and blood of healthy newborns delivered by healthy BCG-vaccinated mothers after normal pregnancy. Of note, vertically transmitted mycobacterial L-forms as a part of placentobiome of the pregnant women didn’t influence the number of resident pathogen-reactive Vδ2 cells. Placenta colonization with mycobacterial L-forms occurs by maternal blood-to-decidua transfer very early in gestation. Together, these data showed that BCG L-forms have the capacity to pass trans-placental barrier and that maternal BCG vaccination affects the placentobiome." @default.
- W2774403566 created "2017-12-22" @default.
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- W2774403566 date "2017-12-12" @default.
- W2774403566 modified "2023-10-10" @default.
- W2774403566 title "Mother-to-newborn transmission of mycobacterial L-forms and Vδ2 T-cell response in placentobiome of BCG-vaccinated pregnant women" @default.
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- W2774403566 cites W1981756981 @default.
- W2774403566 cites W1984282453 @default.
- W2774403566 cites W1987830144 @default.
- W2774403566 cites W1990242316 @default.
- W2774403566 cites W1993132983 @default.
- W2774403566 cites W1995744610 @default.
- W2774403566 cites W1995748945 @default.
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- W2774403566 doi "https://doi.org/10.1038/s41598-017-17644-z" @default.
- W2774403566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5727158" @default.
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- W2774403566 hasPublicationYear "2017" @default.
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