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- W2774452256 abstract "Aim: To assess if hypercholesterolemia depends on etiology of pulmonary hypertension (PH), influenced serum cytokines level, severity of idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic PH (CTEPH) pts. Methods: 22 IPAH pts and 6 CTEPH pts (mean age 47,9+8,55 yrs)(cholesterol level>5,8mmol/l) were enrolled in the study. In all patients coronary artery disease was excluded. The IL-2, IL-4, IL-10, IL-12, TNFa, INF-y levels were analyzed by Bio-Plex Precision Pro. Results: The cholesterol/LDL-C levels in IPAH pts were 6,37+0,37/4,09+0,46 and in CTEPH pts 6,13+0,44 / 3,74+0,47. The lower IL-2 level was observed in CTEPH pts vs IPAH pts (p 6,5mmol/l significant positive correlation between IL-10, INFy, IL-4, IL-12 and syncope frequency (r=0,89;p 7mmol/l the HDL-C had significant negative correlation with systolic PAP (r=-0,99;p Conclusions: The majority of serum cytokines levels didn’t differ between IPAH and CTEPH pts and depended on hypercholesterolemia severity. In IPAH and CTEPH pts the lipid spectrum parameters reflected the severity of disease." @default.
- W2774452256 created "2017-12-22" @default.
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- W2774452256 date "2017-09-01" @default.
- W2774452256 modified "2023-09-27" @default.
- W2774452256 title "Evaluation of serum cytokines in patients with idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension with hypercholesterolemia" @default.
- W2774452256 doi "https://doi.org/10.1183/1393003.congress-2017.pa2413" @default.
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