FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2774541277> ?p ?o ?g. }

• W2774541277 endingPage "20170646" @default.
• W2774541277 startingPage "20170646" @default.
• W2774541277 abstract "Restriction-modification systems are widespread genetic elements that protect bacteria from bacteriophage infections by recognizing and cleaving heterologous DNA at short, well-defined sequences called restriction sites. Bioinformatic evidence shows that restriction sites are significantly underrepresented in bacteriophage genomes, presumably because bacteriophages with fewer restriction sites are more likely to escape cleavage by restriction-modification systems. However, how mutations in restriction sites affect the likelihood of bacteriophage escape is unknown. Using the bacteriophage λ and the restriction-modification system EcoRI, we show that while mutation effects at different restriction sites are unequal, they are independent. As a result, the probability of bacteriophage escape increases with each mutated restriction site. Our results experimentally support the role of restriction site avoidance as a response to selection imposed by restriction-modification systems and offer an insight into the events underlying the process of bacteriophage escape." @default.
• W2774541277 created "2017-12-22" @default.
• W2774541277 creator A5042306442 @default.
• W2774541277 creator A5046318185 @default.
• W2774541277 date "2017-12-01" @default.
• W2774541277 modified "2023-10-18" @default.
• W2774541277 title "Effects of mutations in phage restriction sites during escape from restriction–modification" @default.
• W2774541277 cites W1545338345 @default.
• W2774541277 cites W1741082581 @default.
• W2774541277 cites W1890597695 @default.
• W2774541277 cites W1899868121 @default.
• W2774541277 cites W1966400112 @default.
• W2774541277 cites W1968856189 @default.
• W2774541277 cites W1983158643 @default.
• W2774541277 cites W1988951198 @default.
• W2774541277 cites W1997633079 @default.
• W2774541277 cites W2036005213 @default.
• W2774541277 cites W2040548085 @default.
• W2774541277 cites W2060418270 @default.
• W2774541277 cites W2070190014 @default.
• W2774541277 cites W2121453804 @default.
• W2774541277 cites W2135614314 @default.
• W2774541277 cites W2140848003 @default.
• W2774541277 cites W2147839609 @default.
• W2774541277 cites W2163997813 @default.
• W2774541277 cites W2287773260 @default.
• W2774541277 cites W2465903376 @default.
• W2774541277 cites W2886215442 @default.
• W2774541277 cites W4232271436 @default.
• W2774541277 cites W4238195768 @default.
• W2774541277 doi "https://doi.org/10.1098/rsbl.2017.0646" @default.
• W2774541277 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5746541" @default.
• W2774541277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29237814" @default.
• W2774541277 hasPublicationYear "2017" @default.
• W2774541277 type Work @default.
• W2774541277 sameAs 2774541277 @default.
• W2774541277 citedByCount "28" @default.
• W2774541277 countsByYear W27745412772018 @default.
• W2774541277 countsByYear W27745412772019 @default.
• W2774541277 countsByYear W27745412772020 @default.
• W2774541277 countsByYear W27745412772021 @default.
• W2774541277 countsByYear W27745412772022 @default.
• W2774541277 countsByYear W27745412772023 @default.
• W2774541277 crossrefType "journal-article" @default.
• W2774541277 hasAuthorship W2774541277A5042306442 @default.
• W2774541277 hasAuthorship W2774541277A5046318185 @default.
• W2774541277 hasBestOaLocation W27745412771 @default.
• W2774541277 hasConcept C104317684 @default.
• W2774541277 hasConcept C128319531 @default.
• W2774541277 hasConcept C130123407 @default.
• W2774541277 hasConcept C135763542 @default.
• W2774541277 hasConcept C141231307 @default.
• W2774541277 hasConcept C168007829 @default.
• W2774541277 hasConcept C170673058 @default.
• W2774541277 hasConcept C171636592 @default.
• W2774541277 hasConcept C22744801 @default.
• W2774541277 hasConcept C2776441376 @default.
• W2774541277 hasConcept C2889275 @default.
• W2774541277 hasConcept C501734568 @default.
• W2774541277 hasConcept C54355233 @default.
• W2774541277 hasConcept C547475151 @default.
• W2774541277 hasConcept C552990157 @default.
• W2774541277 hasConcept C58301748 @default.
• W2774541277 hasConcept C84289048 @default.
• W2774541277 hasConcept C86803240 @default.
• W2774541277 hasConceptScore W2774541277C104317684 @default.
• W2774541277 hasConceptScore W2774541277C128319531 @default.
• W2774541277 hasConceptScore W2774541277C130123407 @default.
• W2774541277 hasConceptScore W2774541277C135763542 @default.
• W2774541277 hasConceptScore W2774541277C141231307 @default.
• W2774541277 hasConceptScore W2774541277C168007829 @default.
• W2774541277 hasConceptScore W2774541277C170673058 @default.
• W2774541277 hasConceptScore W2774541277C171636592 @default.
• W2774541277 hasConceptScore W2774541277C22744801 @default.
• W2774541277 hasConceptScore W2774541277C2776441376 @default.
• W2774541277 hasConceptScore W2774541277C2889275 @default.
• W2774541277 hasConceptScore W2774541277C501734568 @default.
• W2774541277 hasConceptScore W2774541277C54355233 @default.
• W2774541277 hasConceptScore W2774541277C547475151 @default.
• W2774541277 hasConceptScore W2774541277C552990157 @default.
• W2774541277 hasConceptScore W2774541277C58301748 @default.
• W2774541277 hasConceptScore W2774541277C84289048 @default.
• W2774541277 hasConceptScore W2774541277C86803240 @default.
• W2774541277 hasFunder F4320320338 @default.
• W2774541277 hasFunder F4320321004 @default.
• W2774541277 hasIssue "12" @default.
• W2774541277 hasLocation W27745412771 @default.
• W2774541277 hasLocation W27745412772 @default.
• W2774541277 hasLocation W27745412773 @default.
• W2774541277 hasLocation W27745412774 @default.
• W2774541277 hasOpenAccess W2774541277 @default.
• W2774541277 hasPrimaryLocation W27745412771 @default.
• W2774541277 hasRelatedWork W1535846985 @default.
• W2774541277 hasRelatedWork W1547373343 @default.
• W2774541277 hasRelatedWork W1834210965 @default.
• W2774541277 hasRelatedWork W1969078876 @default.
• W2774541277 hasRelatedWork W1973861642 @default.
• W2774541277 hasRelatedWork W2026548960 @default.

• next