FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2774861105> ?p ?o ?g. }

• W2774861105 endingPage "14" @default.
• W2774861105 startingPage "4" @default.
• W2774861105 abstract "The incidence and prevalence of vitamin D deficiency are increasing worldwide. It is estimated that over 50% of the world's population have low vitamin D (i.e., hypovitaminosis D; serum levels below 30 ng/mL). In vitamin D inadequacy, human physiological systems work inefficiently. In humans, 80% of the vitamin D is synthesized in the presence of ultraviolet rays from sunlight; for the rest, we rely on diet and nowadays, supplements. The latter becomes important when one is exposed to less than optimal amounts of sunlight, inability to generate vitamin D in the skin efficiently, and/or having conditions that lead to decreased intestinal absorption or increased catabolism of vitamin D. The normal serum 25-hydroxyvitamin D [25(OH)D] level is around 30 ng/mL (75 nmol/L) and the optimal range is between 30 and 60 ng/mL (75-150 nmol/L). In 2011, the Institute of Medicine (IOM) suggested that 600IU of vitamin D is adequate for people below age 71 who are not exposed to sunshine. Although this might be relevant to the ambulatory healthy white Caucasians to achieve serum 25(OH)D level of 20 ng/mL, but it is insufficient for other ethnic groups. Moreover, the IOM recommendations are not suitable for those who live outside North America. Vitamin D requirements are higher during adolescence, pregnancy and lactation, and in many other disease conditions. Most clinicians consider 30 ng/mL as the minimum serum level of 25(OH)D necessary to maintain good health. In the absence of sunlight exposure and with daily oral intake of 600IU vitamin D, very few people would reach serum 25(OH)D level above 30 ng/mL. While an additional daily intake of 1000IU of vitamin D are required for people with lighter-skin color, those with darker complexion and the elderly, require a minimum of 2000IU/day to maintain serum 25(OH)D levels over 30 ng/mL; 5000 IU/day supplement is considered as the safe daily upper limit of supplementation. Vulnerable groups such as the disabled and/or house-bound, obese, with gastrointestinal abnormalities and/or malabsorption syndromes, institutionalized people (e.g., nursing homes, prisons, etc.), and pregnant and lactating women need approximately 4000IU per day for optimal physiological activity. Vitamin D is essential for gastrointestinal calcium absorption, mineralization of osteoid tissue and maintenance of serum ionized calcium level. It is also important for other physiological functions, such as muscle strength, neuromuscular coordination, hormone release, subduing autoimmunity, and curtailing the development of certain cancers." @default.
• W2774861105 created "2017-12-22" @default.
• W2774861105 creator A5010105721 @default.
• W2774861105 creator A5044248592 @default.
• W2774861105 creator A5079459526 @default.
• W2774861105 date "2018-06-01" @default.
• W2774861105 modified "2023-10-01" @default.
• W2774861105 title "Calcium and vitamin D in human health: Hype or real?" @default.
• W2774861105 cites W1551028857 @default.
• W2774861105 cites W1558686508 @default.
• W2774861105 cites W1582960075 @default.
• W2774861105 cites W1824301024 @default.
• W2774861105 cites W1849648692 @default.
• W2774861105 cites W1911104948 @default.
• W2774861105 cites W1945973372 @default.
• W2774861105 cites W1952582346 @default.
• W2774861105 cites W1959271091 @default.
• W2774861105 cites W1964157487 @default.
• W2774861105 cites W1964578526 @default.
• W2774861105 cites W1965062422 @default.
• W2774861105 cites W1968160337 @default.
• W2774861105 cites W1971048248 @default.
• W2774861105 cites W1974125594 @default.
• W2774861105 cites W1974357084 @default.
• W2774861105 cites W1979851666 @default.
• W2774861105 cites W1981027540 @default.
• W2774861105 cites W1982881554 @default.
• W2774861105 cites W1984005450 @default.
• W2774861105 cites W1984796664 @default.
• W2774861105 cites W1984903049 @default.
• W2774861105 cites W1985420924 @default.
• W2774861105 cites W1988779242 @default.
• W2774861105 cites W1996451149 @default.
• W2774861105 cites W2003465607 @default.
• W2774861105 cites W2005247866 @default.
• W2774861105 cites W2012448954 @default.
• W2774861105 cites W2013753233 @default.
• W2774861105 cites W2018006483 @default.
• W2774861105 cites W2019558876 @default.
• W2774861105 cites W2022809525 @default.
• W2774861105 cites W2023823962 @default.
• W2774861105 cites W2024693050 @default.
• W2774861105 cites W2026647959 @default.
• W2774861105 cites W2027245705 @default.
• W2774861105 cites W2027990211 @default.
• W2774861105 cites W2028673944 @default.
• W2774861105 cites W2028897817 @default.
• W2774861105 cites W2034653828 @default.
• W2774861105 cites W2038293689 @default.
• W2774861105 cites W2038547346 @default.
• W2774861105 cites W2040837263 @default.
• W2774861105 cites W2044096070 @default.
• W2774861105 cites W2048548452 @default.
• W2774861105 cites W2048724836 @default.
• W2774861105 cites W2055630167 @default.
• W2774861105 cites W2056247628 @default.
• W2774861105 cites W2059512911 @default.
• W2774861105 cites W2064219897 @default.
• W2774861105 cites W2069811152 @default.
• W2774861105 cites W2074347967 @default.
• W2774861105 cites W2082363650 @default.
• W2774861105 cites W2090239878 @default.
• W2774861105 cites W2090993145 @default.
• W2774861105 cites W2096150705 @default.
• W2774861105 cites W2101206762 @default.
• W2774861105 cites W2101737661 @default.
• W2774861105 cites W2101805185 @default.
• W2774861105 cites W2103024679 @default.
• W2774861105 cites W2106402853 @default.
• W2774861105 cites W2106606013 @default.
• W2774861105 cites W2107905356 @default.
• W2774861105 cites W2114800972 @default.
• W2774861105 cites W2116158894 @default.
• W2774861105 cites W2116328650 @default.
• W2774861105 cites W2116841061 @default.
• W2774861105 cites W2118540989 @default.
• W2774861105 cites W2119739932 @default.
• W2774861105 cites W2120568689 @default.
• W2774861105 cites W2121080036 @default.
• W2774861105 cites W2122319016 @default.
• W2774861105 cites W2122398315 @default.
• W2774861105 cites W2122939880 @default.
• W2774861105 cites W2124070987 @default.
• W2774861105 cites W2125752591 @default.
• W2774861105 cites W2127347194 @default.
• W2774861105 cites W2131264460 @default.
• W2774861105 cites W2133060411 @default.
• W2774861105 cites W2133817813 @default.
• W2774861105 cites W2134433004 @default.
• W2774861105 cites W2138299718 @default.
• W2774861105 cites W2138441422 @default.
• W2774861105 cites W2138962072 @default.
• W2774861105 cites W2140081047 @default.
• W2774861105 cites W2142104529 @default.
• W2774861105 cites W2142971300 @default.
• W2774861105 cites W2144876084 @default.
• W2774861105 cites W2145798427 @default.
• W2774861105 cites W2149175313 @default.

• next