FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2775150884> ?p ?o ?g. }

• W2775150884 abstract "Abstract Increased availability of data and accessibility of computational tools in recent years have created an unprecedented upsurge of scientific studies driven by statistical analysis. Limitations inherent to statistics impose constraints on the reliability of conclusions drawn from data, so misuse of statistical methods is a growing concern. Hypothesis and significance testing, and the accompanying P -values are being scrutinized as representing the most widely applied and abused practices. One line of critique is that P -values are inherently unfit to fulfill their ostensible role as measures of credibility for scientific hypotheses. It has also been suggested that while P -values may have their role as summary measures of effect, researchers underappreciate the degree of randomness in the P -value. High variability of P -values would suggest that having obtained a small P -value in one study, one is, ne vertheless, still likely to obtain a much larger P -value in a similarly powered replication study. Thus, “replicability of P -value” is in itself questionable. To characterize P -value variability, one can use prediction intervals whose endpoints reflect the likely spread of P -values that could have been obtained by a replication study. Unfortunately, the intervals currently in use, the frequentist P -intervals, are based on unrealistic implicit assumptions. Namely, P -intervals are constructed with the assumptions that imply substantial chances of encountering large values of effect size in an observational study, which leads to bias. The long-run frequentist probability provided by P -intervals is similar in interpretation to that of the classical confidence intervals, but the endpoints of any particular interval lack interpretation as probabilistic bounds for the possible spread of future P -values that may have been obtained in replication studies. Along with classical frequentist intervals, there exists a Bayesian viewpoint toward interval construction in which the endpoints of an interval have a meaningful probabilistic interpretation. We propose Bayesian intervals for prediction of P -value variability in prospective replication studies. Contingent upon approximate prior knowledge of the effect size distribution, our proposed Bayesian intervals have endpoints that are directly interpretable as probabilistic bounds for replication P -values, and they are resistant to selection bias. We showcase our approach by its application to P -values reported for five psychiatric disorders by the Psychiatric Genomics Consortium group." @default.
• W2775150884 created "2017-12-22" @default.
• W2775150884 creator A5015631353 @default.
• W2775150884 creator A5017899777 @default.
• W2775150884 creator A5090157678 @default.
• W2775150884 date "2017-12-08" @default.
• W2775150884 modified "2023-09-26" @default.
• W2775150884 title "Bayesian prediction intervals for assessing P-value variability in prospective replication studies" @default.
• W2775150884 cites W1972553673 @default.
• W2775150884 cites W1991882349 @default.
• W2775150884 cites W2033125161 @default.
• W2775150884 cites W2033495650 @default.
• W2775150884 cites W2036815268 @default.
• W2775150884 cites W2042125492 @default.
• W2775150884 cites W2049978950 @default.
• W2775150884 cites W2073157712 @default.
• W2775150884 cites W2075418882 @default.
• W2775150884 cites W2089207825 @default.
• W2775150884 cites W2092640107 @default.
• W2775150884 cites W2097656361 @default.
• W2775150884 cites W2101252157 @default.
• W2775150884 cites W2114688149 @default.
• W2775150884 cites W2138069158 @default.
• W2775150884 cites W2144712959 @default.
• W2775150884 cites W2144981148 @default.
• W2775150884 cites W2164544914 @default.
• W2775150884 cites W2167619573 @default.
• W2775150884 cites W2283498606 @default.
• W2775150884 cites W2293040502 @default.
• W2775150884 cites W307360663 @default.
• W2775150884 doi "https://doi.org/10.1038/s41398-017-0024-3" @default.
• W2775150884 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5802740" @default.
• W2775150884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29217835" @default.
• W2775150884 hasPublicationYear "2017" @default.
• W2775150884 type Work @default.
• W2775150884 sameAs 2775150884 @default.
• W2775150884 citedByCount "4" @default.
• W2775150884 countsByYear W27751508842018 @default.
• W2775150884 countsByYear W27751508842019 @default.
• W2775150884 countsByYear W27751508842021 @default.
• W2775150884 crossrefType "journal-article" @default.
• W2775150884 hasAuthorship W2775150884A5015631353 @default.
• W2775150884 hasAuthorship W2775150884A5017899777 @default.
• W2775150884 hasAuthorship W2775150884A5090157678 @default.
• W2775150884 hasBestOaLocation W27751508841 @default.
• W2775150884 hasConcept C105795698 @default.
• W2775150884 hasConcept C107673813 @default.
• W2775150884 hasConcept C111472728 @default.
• W2775150884 hasConcept C121117317 @default.
• W2775150884 hasConcept C121332964 @default.
• W2775150884 hasConcept C125112378 @default.
• W2775150884 hasConcept C12590798 @default.
• W2775150884 hasConcept C138885662 @default.
• W2775150884 hasConcept C149782125 @default.
• W2775150884 hasConcept C15744967 @default.
• W2775150884 hasConcept C160234255 @default.
• W2775150884 hasConcept C162376815 @default.
• W2775150884 hasConcept C163258240 @default.
• W2775150884 hasConcept C23131810 @default.
• W2775150884 hasConcept C2776291640 @default.
• W2775150884 hasConcept C2780224610 @default.
• W2775150884 hasConcept C33923547 @default.
• W2775150884 hasConcept C43214815 @default.
• W2775150884 hasConcept C44036329 @default.
• W2775150884 hasConcept C44249647 @default.
• W2775150884 hasConcept C62520636 @default.
• W2775150884 hasConcept C75455068 @default.
• W2775150884 hasConcept C87007009 @default.
• W2775150884 hasConceptScore W2775150884C105795698 @default.
• W2775150884 hasConceptScore W2775150884C107673813 @default.
• W2775150884 hasConceptScore W2775150884C111472728 @default.
• W2775150884 hasConceptScore W2775150884C121117317 @default.
• W2775150884 hasConceptScore W2775150884C121332964 @default.
• W2775150884 hasConceptScore W2775150884C125112378 @default.
• W2775150884 hasConceptScore W2775150884C12590798 @default.
• W2775150884 hasConceptScore W2775150884C138885662 @default.
• W2775150884 hasConceptScore W2775150884C149782125 @default.
• W2775150884 hasConceptScore W2775150884C15744967 @default.
• W2775150884 hasConceptScore W2775150884C160234255 @default.
• W2775150884 hasConceptScore W2775150884C162376815 @default.
• W2775150884 hasConceptScore W2775150884C163258240 @default.
• W2775150884 hasConceptScore W2775150884C23131810 @default.
• W2775150884 hasConceptScore W2775150884C2776291640 @default.
• W2775150884 hasConceptScore W2775150884C2780224610 @default.
• W2775150884 hasConceptScore W2775150884C33923547 @default.
• W2775150884 hasConceptScore W2775150884C43214815 @default.
• W2775150884 hasConceptScore W2775150884C44036329 @default.
• W2775150884 hasConceptScore W2775150884C44249647 @default.
• W2775150884 hasConceptScore W2775150884C62520636 @default.
• W2775150884 hasConceptScore W2775150884C75455068 @default.
• W2775150884 hasConceptScore W2775150884C87007009 @default.
• W2775150884 hasIssue "12" @default.
• W2775150884 hasLocation W27751508841 @default.
• W2775150884 hasLocation W27751508842 @default.
• W2775150884 hasLocation W27751508843 @default.
• W2775150884 hasLocation W27751508844 @default.
• W2775150884 hasLocation W27751508845 @default.
• W2775150884 hasLocation W27751508846 @default.
• W2775150884 hasOpenAccess W2775150884 @default.
• W2775150884 hasPrimaryLocation W27751508841 @default.

• next