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- W2775185847 startingPage "139" @default.
- W2775185847 abstract "Since the introduction of the concept of borderline resectable pancreatic cancer (BRPC), various definitions of this disease entity have been suggested. However, there are several obstacles in defining this disease category. The current diagnostic criteria of BRPC mainly focuses on its expanded ‘technical resectability’; however, they are difficult to interpret because of their ambiguity using potential subjective or arbitrary terminology, In addition, limitations in current imaging technology and a lack of evidence in radiological-pathological-clinical correlation make it difficult to refine the criteria. On the other hand, neoadjuvant treatment is usually applied to increase the R0 resection rate of BRPC focusing on the ‘oncological curability’. However, evidence is needed concerning the effect of neoadjuvant treatment by quality-controlled prospective randomized clinical trials based on a standardized radiologic and pathologic reporting system. In conclusion, there are two aspects in the current concept of BRPC, which are technical resectability and oncological curability. Although the recent evolution of surgical techniques is expanding the scope of technical resectability, it should not be overlooked that the disease entity must be defined based on the evidence of oncological curability." @default.
- W2775185847 created "2017-12-22" @default.
- W2775185847 creator A5008731225 @default.
- W2775185847 creator A5024933931 @default.
- W2775185847 creator A5029996030 @default.
- W2775185847 creator A5078630835 @default.
- W2775185847 date "2018-03-01" @default.
- W2775185847 modified "2023-10-16" @default.
- W2775185847 title "Clinical significance of defining borderline resectable pancreatic cancer" @default.
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