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- W2775289715 abstract "In polycystic ovary syndrome (PCOS), myo-inositol (MI) supplements have shown many beneficial effects. In this study, therefore, we aimed to investigate the serum level of myo-inositol oxygenase (MIOX), which is the only enzyme catalyzing MI in vivo, in patients with PCOS. Serum MIOX enzyme levels and other laboratory parameters were compared between sixty patients, who were diagnosed with PCOS for the first time, and sixty healthy individuals at similar age and sex. MIOX serum levels were not different between two groups (p = 0.7428). MIOX median and 95% CI were 19.4 and 10.6-39.1 in the control group and 16.4 and 7.6-46.2 in the patient group respectively. Demographic data, biochemical and hematological parameters, hormone parameters were not different except from the lymphocyte count between the two groups. Lymphocyte count was higher in the patient group. Although the ratio of LH/FSH was higher in the patient group, it was not statistically significant. Our results suggest that serum MIOX levels do not change in PCOS. It was, therefore, concluded that MI deficiency observed in PCOS was not related to the level of MIOX enzyme which cleaves MI." @default.
- W2775289715 created "2017-12-22" @default.
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- W2775289715 date "2017-11-29" @default.
- W2775289715 modified "2023-10-14" @default.
- W2775289715 title "Does <i>myo</i>-inositol oxygenase, the only enzyme to catalyze <i>myo</i>-inositol <i>in vivo</i>, play a role in the etiology of polycystic ovarian syndrome?" @default.
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- W2775289715 doi "https://doi.org/10.1080/09513590.2017.1409710" @default.
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