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• W2775362208 endingPage "R508" @default.
• W2775362208 startingPage "R499" @default.
• W2775362208 abstract "Preeclampsia affects up to 8% of pregnancies worldwide and is a leading cause of both maternal and fetal morbidity and mortality. Our current understanding of the cause(s) of preeclampsia is far from complete, and the lack of a single reliable animal model that recapitulates all aspects of the disease further confounds our understanding. This is partially due to the heterogeneous nature of the disease, coupled with our evolving understanding of its etiology. Nevertheless, animal models are still highly relevant and useful tools that help us better understand the pathophysiology of specific aspects of preeclampsia. This review summarizes the various types and characteristics of animal models used to study preeclampsia, highlighting particular features of these models relevant to clinical translation. This review points out the strengths and limitations of these models to illustrate the importance of using the appropriate model depending on the research question." @default.
• W2775362208 created "2017-12-22" @default.
• W2775362208 creator A5023970323 @default.
• W2775362208 creator A5040172468 @default.
• W2775362208 creator A5062361099 @default.
• W2775362208 creator A5062943826 @default.
• W2775362208 creator A5083179380 @default.
• W2775362208 creator A5091649592 @default.
• W2775362208 date "2018-04-01" @default.
• W2775362208 modified "2023-10-18" @default.
• W2775362208 title "Animal models of preeclampsia: translational failings and why" @default.
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