FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2775495518> ?p ?o ?g. }

• W2775495518 abstract "Abstract Introduction Achieving viral suppression is key in the global strategy to end the HIV epidemic. However, the levels of viral suppression have yet to be described in many resource‐limited settings. Methods We investigated the time to virologic failure (VF; defined as a viral load of ≥1000 copies/ml) and changes in CD4 counts since starting antiretroviral therapy (ART) in a cohort of HIV‐infected adults in Hanoi, Vietnam. Factors related to the time to VF and impaired early immune recovery (defined as not attaining an increase in 100 cells/mm 3 in CD4 counts at 24 months) were further analysed. Results From 1806 participants, 225 were identified as having VF at a median of 50 months of first‐line ART. The viral suppression rate at 12 months was 95.5% and survival without VF was maintained above 90% until 42 months. An increase in CD4 counts from the baseline was greater in groups with lower baseline CD4 counts. A younger age (multivariate hazard ratio (HR) 0.75, vs. <30), hepatitis C (HCV)‐antibody positivity (HR 1.43), and stavudine (d4T)‐containing regimens (HR 1.4, vs. zidovudine (AZT)) were associated with earlier VF. Factors associated with impaired early immune recovery included the male sex (odds ratio (OR) 1.78), HCV‐antibody positivity (OR 1.72), d4T‐based regimens (OR 0.51, vs. AZT), and nevirapine‐based regimens (OR 0.53, vs. efavirenz) after controlling for baseline CD4 counts. Conclusion Durable high‐rate viral suppression was observed in the cohort of patients on first‐line ART in Vietnam. Our results highlight the need to increase adherence support among injection drug users and HCV co‐infected patients." @default.
• W2775495518 created "2017-12-22" @default.
• W2775495518 creator A5017084808 @default.
• W2775495518 creator A5028059399 @default.
• W2775495518 creator A5030827890 @default.
• W2775495518 creator A5047624353 @default.
• W2775495518 creator A5056261780 @default.
• W2775495518 creator A5056977303 @default.
• W2775495518 creator A5072097342 @default.
• W2775495518 creator A5072705373 @default.
• W2775495518 creator A5075109760 @default.
• W2775495518 creator A5076197621 @default.
• W2775495518 date "2017-12-01" @default.
• W2775495518 modified "2023-10-01" @default.
• W2775495518 title "Long-term viral suppression and immune recovery during first-line antiretroviral therapy: a study of an HIV-infected adult cohort in Hanoi, Vietnam" @default.
• W2775495518 cites W1474931616 @default.
• W2775495518 cites W1997321745 @default.
• W2775495518 cites W2002716081 @default.
• W2775495518 cites W2007384621 @default.
• W2775495518 cites W2009180434 @default.
• W2775495518 cites W2018253571 @default.
• W2775495518 cites W2021172533 @default.
• W2775495518 cites W2026207295 @default.
• W2775495518 cites W2028029127 @default.
• W2775495518 cites W2061411675 @default.
• W2775495518 cites W2074454030 @default.
• W2775495518 cites W2076663478 @default.
• W2775495518 cites W2105064834 @default.
• W2775495518 cites W2108282931 @default.
• W2775495518 cites W2111327516 @default.
• W2775495518 cites W2113642360 @default.
• W2775495518 cites W2116049857 @default.
• W2775495518 cites W2132941341 @default.
• W2775495518 cites W2144361427 @default.
• W2775495518 cites W2152505869 @default.
• W2775495518 cites W2152830821 @default.
• W2775495518 cites W2153370925 @default.
• W2775495518 cites W2158842834 @default.
• W2775495518 cites W2264428987 @default.
• W2775495518 cites W2290187994 @default.
• W2775495518 doi "https://doi.org/10.1002/jia2.25030" @default.
• W2775495518 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5810334" @default.
• W2775495518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29211347" @default.
• W2775495518 hasPublicationYear "2017" @default.
• W2775495518 type Work @default.
• W2775495518 sameAs 2775495518 @default.
• W2775495518 citedByCount "15" @default.
• W2775495518 countsByYear W27754955182018 @default.
• W2775495518 countsByYear W27754955182019 @default.
• W2775495518 countsByYear W27754955182020 @default.
• W2775495518 countsByYear W27754955182021 @default.
• W2775495518 countsByYear W27754955182023 @default.
• W2775495518 crossrefType "journal-article" @default.
• W2775495518 hasAuthorship W2775495518A5017084808 @default.
• W2775495518 hasAuthorship W2775495518A5028059399 @default.
• W2775495518 hasAuthorship W2775495518A5030827890 @default.
• W2775495518 hasAuthorship W2775495518A5047624353 @default.
• W2775495518 hasAuthorship W2775495518A5056261780 @default.
• W2775495518 hasAuthorship W2775495518A5056977303 @default.
• W2775495518 hasAuthorship W2775495518A5072097342 @default.
• W2775495518 hasAuthorship W2775495518A5072705373 @default.
• W2775495518 hasAuthorship W2775495518A5075109760 @default.
• W2775495518 hasAuthorship W2775495518A5076197621 @default.
• W2775495518 hasBestOaLocation W27754955181 @default.
• W2775495518 hasConcept C126322002 @default.
• W2775495518 hasConcept C142462285 @default.
• W2775495518 hasConcept C203014093 @default.
• W2775495518 hasConcept C207103383 @default.
• W2775495518 hasConcept C2779130552 @default.
• W2775495518 hasConcept C2779889181 @default.
• W2775495518 hasConcept C2780216070 @default.
• W2775495518 hasConcept C2780727368 @default.
• W2775495518 hasConcept C2781413609 @default.
• W2775495518 hasConcept C2781432083 @default.
• W2775495518 hasConcept C2993143319 @default.
• W2775495518 hasConcept C3013748606 @default.
• W2775495518 hasConcept C44249647 @default.
• W2775495518 hasConcept C71924100 @default.
• W2775495518 hasConcept C72563966 @default.
• W2775495518 hasConceptScore W2775495518C126322002 @default.
• W2775495518 hasConceptScore W2775495518C142462285 @default.
• W2775495518 hasConceptScore W2775495518C203014093 @default.
• W2775495518 hasConceptScore W2775495518C207103383 @default.
• W2775495518 hasConceptScore W2775495518C2779130552 @default.
• W2775495518 hasConceptScore W2775495518C2779889181 @default.
• W2775495518 hasConceptScore W2775495518C2780216070 @default.
• W2775495518 hasConceptScore W2775495518C2780727368 @default.
• W2775495518 hasConceptScore W2775495518C2781413609 @default.
• W2775495518 hasConceptScore W2775495518C2781432083 @default.
• W2775495518 hasConceptScore W2775495518C2993143319 @default.
• W2775495518 hasConceptScore W2775495518C3013748606 @default.
• W2775495518 hasConceptScore W2775495518C44249647 @default.
• W2775495518 hasConceptScore W2775495518C71924100 @default.
• W2775495518 hasConceptScore W2775495518C72563966 @default.
• W2775495518 hasFunder F4320311405 @default.
• W2775495518 hasIssue "4" @default.
• W2775495518 hasLocation W27754955181 @default.
• W2775495518 hasLocation W27754955182 @default.
• W2775495518 hasLocation W27754955183 @default.
• W2775495518 hasLocation W27754955184 @default.

• next