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• W2775502046 abstract "Background Statins are among the most commonly used medications in the United States, and statin use is associated with increased risk of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). However, previous studies are limited by lack of adjustment for important confounders. Objective Examine the relation between statins and skin cancer risk in the Nurses' Health Study and Health Professionals Follow-up Study. Methods Cox proportional hazards regression was used to evaluate associations. Results During follow-up (2000-2010), we documented 10,201 BCC, 1393 SCC, and 333 melanoma cases. History of high cholesterol level was not associated with risk of BCC (pooled multivariable-adjusted hazard ratio [HR], 1.04; 95% confidence interval [CI], 1.00-1.09), SCC (HR, 0.95; 95% CI, 0.85-1.06), or melanoma (HR, 0.87; 95% CI, 0.64-1.19). Statin use was not associated with risk of BCC (HR, 1.04; 95% CI, 0.99-1.09]), SCC (HR, 1.08; 95% CI, 0.94-1.24), or melanoma (HR, 1.04; 95% CI, 0.78-1.38). There was a trend toward higher BCC risk with longer duration of statin use in men (P trend = .003) but not in women (P trend = .86). Limitations Lack of treatment data. Conclusion History of high cholesterol level was not associated with skin cancer risk. Longer duration of statin use was associated with a trend toward higher BCC risk in men. Statins are among the most commonly used medications in the United States, and statin use is associated with increased risk of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). However, previous studies are limited by lack of adjustment for important confounders. Examine the relation between statins and skin cancer risk in the Nurses' Health Study and Health Professionals Follow-up Study. Cox proportional hazards regression was used to evaluate associations. During follow-up (2000-2010), we documented 10,201 BCC, 1393 SCC, and 333 melanoma cases. History of high cholesterol level was not associated with risk of BCC (pooled multivariable-adjusted hazard ratio [HR], 1.04; 95% confidence interval [CI], 1.00-1.09), SCC (HR, 0.95; 95% CI, 0.85-1.06), or melanoma (HR, 0.87; 95% CI, 0.64-1.19). Statin use was not associated with risk of BCC (HR, 1.04; 95% CI, 0.99-1.09]), SCC (HR, 1.08; 95% CI, 0.94-1.24), or melanoma (HR, 1.04; 95% CI, 0.78-1.38). There was a trend toward higher BCC risk with longer duration of statin use in men (P trend = .003) but not in women (P trend = .86). Lack of treatment data. History of high cholesterol level was not associated with skin cancer risk. Longer duration of statin use was associated with a trend toward higher BCC risk in men." @default.
• W2775502046 created "2017-12-22" @default.
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• W2775502046 date "2018-04-01" @default.
• W2775502046 modified "2023-10-13" @default.
• W2775502046 title "Statin use and risk of skin cancer" @default.
• W2775502046 cites W142100601 @default.
• W2775502046 cites W1490394333 @default.
• W2775502046 cites W1851566198 @default.
• W2775502046 cites W1934272095 @default.
• W2775502046 cites W1958805324 @default.
• W2775502046 cites W1964080164 @default.
• W2775502046 cites W1965431780 @default.
• W2775502046 cites W1967280935 @default.
• W2775502046 cites W1967588809 @default.
• W2775502046 cites W1977494231 @default.
• W2775502046 cites W1985245026 @default.
• W2775502046 cites W1987052093 @default.
• W2775502046 cites W1990591488 @default.
• W2775502046 cites W1992975936 @default.
• W2775502046 cites W2014393189 @default.
• W2775502046 cites W2020830322 @default.
• W2775502046 cites W2021879218 @default.
• W2775502046 cites W2026375486 @default.
• W2775502046 cites W2027236010 @default.
• W2775502046 cites W2032275493 @default.
• W2775502046 cites W2038338711 @default.
• W2775502046 cites W2038858817 @default.
• W2775502046 cites W2043381098 @default.
• W2775502046 cites W2047750430 @default.
• W2775502046 cites W2048396772 @default.
• W2775502046 cites W2049284605 @default.
• W2775502046 cites W2054333100 @default.
• W2775502046 cites W2057674977 @default.
• W2775502046 cites W2062210994 @default.
• W2775502046 cites W2063007022 @default.
• W2775502046 cites W2065461844 @default.
• W2775502046 cites W2068695763 @default.
• W2775502046 cites W2071400261 @default.
• W2775502046 cites W2073105584 @default.
• W2775502046 cites W2073310848 @default.
• W2775502046 cites W2074484695 @default.
• W2775502046 cites W2076864596 @default.
• W2775502046 cites W2078725182 @default.
• W2775502046 cites W2083701433 @default.
• W2775502046 cites W2087327978 @default.
• W2775502046 cites W2088578081 @default.
• W2775502046 cites W2098547698 @default.
• W2775502046 cites W2100839274 @default.
• W2775502046 cites W2108475180 @default.
• W2775502046 cites W2114164056 @default.
• W2775502046 cites W2118147959 @default.
• W2775502046 cites W2120021843 @default.
• W2775502046 cites W2128094646 @default.
• W2775502046 cites W2129732555 @default.
• W2775502046 cites W2131778873 @default.
• W2775502046 cites W2148521326 @default.
• W2775502046 cites W2149626514 @default.
• W2775502046 cites W2158187071 @default.
• W2775502046 cites W2165360932 @default.
• W2775502046 cites W2165855078 @default.
• W2775502046 cites W2166045336 @default.
• W2775502046 cites W2166481344 @default.
• W2775502046 cites W2169820120 @default.
• W2775502046 cites W2193527277 @default.
• W2775502046 cites W2223526704 @default.
• W2775502046 cites W2419251448 @default.
• W2775502046 cites W2482687042 @default.
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• W2775502046 doi "https://doi.org/10.1016/j.jaad.2017.11.050" @default.
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