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- W2775551194 endingPage "139" @default.
- W2775551194 startingPage "114" @default.
- W2775551194 abstract "This review summarises current understanding of how bone is sculpted through adaptive processes, designed to meet the mechanical challenges it faces in everyday life and athletic pursuits, serving as an update for clinicians, researchers and physical therapists. Bone's ability to resist fracture under the large muscle and locomotory forces it experiences during movement and in falls or collisions is dependent on its established mechanical properties, determined by bone's complex and multidimensional material and structural organisation. At all levels, bone is highly adaptive to habitual loading, regulating its structure according to components of its loading regime and mechanical environment, inclusive of strain magnitude, rate, frequency, distribution and deformation mode. Indeed, the greatest forces habitually applied to bone arise from muscular contractions, and the past two decades have seen substantial advances in our understanding of how these forces shape bone throughout life. Herein, we also highlight the limitations of in vivo methods to assess and understand bone collagen, and bone mineral at the material or tissue level. The inability to easily measure or closely regulate applied strain in humans is identified, limiting the translation of animal studies to human populations, and our exploration of how components of mechanical loading regimes influence mechanoadaptation." @default.
- W2775551194 created "2017-12-22" @default.
- W2775551194 creator A5044718208 @default.
- W2775551194 creator A5053664052 @default.
- W2775551194 creator A5068509918 @default.
- W2775551194 creator A5077861705 @default.
- W2775551194 creator A5088881556 @default.
- W2775551194 date "2017-09-01" @default.
- W2775551194 modified "2023-10-16" @default.
- W2775551194 title "Mechanical basis of bone strength: influence of bone material, bone structure and muscle action." @default.
- W2775551194 cites W1218970471 @default.
- W2775551194 cites W1427116170 @default.
- W2775551194 cites W1480870442 @default.
- W2775551194 cites W1493214657 @default.
- W2775551194 cites W1497444618 @default.
- W2775551194 cites W1524656751 @default.
- W2775551194 cites W1551954102 @default.
- W2775551194 cites W1557633471 @default.
- W2775551194 cites W1566641143 @default.
- W2775551194 cites W1568977955 @default.
- W2775551194 cites W1576728932 @default.
- W2775551194 cites W1705747559 @default.
- W2775551194 cites W1717431484 @default.
- W2775551194 cites W179618624 @default.
- W2775551194 cites W1841227076 @default.
- W2775551194 cites W1868877217 @default.
- W2775551194 cites W1936633632 @default.
- W2775551194 cites W1938769353 @default.
- W2775551194 cites W1964465273 @default.
- W2775551194 cites W1964478925 @default.
- W2775551194 cites W1964517483 @default.
- W2775551194 cites W1965597544 @default.
- W2775551194 cites W1965677499 @default.
- W2775551194 cites W1967012185 @default.
- W2775551194 cites W1968379749 @default.
- W2775551194 cites W1968536205 @default.
- W2775551194 cites W1969619610 @default.
- W2775551194 cites W1970550845 @default.
- W2775551194 cites W1970676313 @default.
- W2775551194 cites W1970693175 @default.
- W2775551194 cites W1971139554 @default.
- W2775551194 cites W1971915656 @default.
- W2775551194 cites W1972050610 @default.
- W2775551194 cites W1972451730 @default.
- W2775551194 cites W1973420112 @default.
- W2775551194 cites W1973611633 @default.
- W2775551194 cites W1973834690 @default.
- W2775551194 cites W1974725047 @default.
- W2775551194 cites W1975568057 @default.
- W2775551194 cites W1975593357 @default.
- W2775551194 cites W1976282528 @default.
- W2775551194 cites W1976548401 @default.
- W2775551194 cites W1976838605 @default.
- W2775551194 cites W1977870976 @default.
- W2775551194 cites W1979105043 @default.
- W2775551194 cites W1980292839 @default.
- W2775551194 cites W1981333978 @default.
- W2775551194 cites W1981380728 @default.
- W2775551194 cites W1982195212 @default.
- W2775551194 cites W1982254486 @default.
- W2775551194 cites W1982563976 @default.
- W2775551194 cites W1982926533 @default.
- W2775551194 cites W1983247815 @default.
- W2775551194 cites W1983728677 @default.
- W2775551194 cites W1983954964 @default.
- W2775551194 cites W1984119358 @default.
- W2775551194 cites W1984247841 @default.
- W2775551194 cites W1984579670 @default.
- W2775551194 cites W1984721835 @default.
- W2775551194 cites W1985227590 @default.
- W2775551194 cites W1985270712 @default.
- W2775551194 cites W1985695678 @default.
- W2775551194 cites W1986131567 @default.
- W2775551194 cites W1986324959 @default.
- W2775551194 cites W1986327818 @default.
- W2775551194 cites W1986746924 @default.
- W2775551194 cites W1988118165 @default.
- W2775551194 cites W1988216227 @default.
- W2775551194 cites W1988354324 @default.
- W2775551194 cites W1988381813 @default.
- W2775551194 cites W1988582828 @default.
- W2775551194 cites W1988802004 @default.
- W2775551194 cites W1990403069 @default.
- W2775551194 cites W1990723730 @default.
- W2775551194 cites W1991600192 @default.
- W2775551194 cites W1992224892 @default.
- W2775551194 cites W1992882775 @default.
- W2775551194 cites W1993090130 @default.
- W2775551194 cites W1993226426 @default.
- W2775551194 cites W1993275768 @default.
- W2775551194 cites W1993536799 @default.
- W2775551194 cites W1994074007 @default.
- W2775551194 cites W1994597310 @default.
- W2775551194 cites W1995972008 @default.
- W2775551194 cites W1996767803 @default.
- W2775551194 cites W1997275506 @default.
- W2775551194 cites W1998111806 @default.
- W2775551194 cites W1998314216 @default.