FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2775571816> ?p ?o ?g. }

• W2775571816 abstract "The hand is one of the most sophisticated biological motor systems and understanding the control strategies used by the brain to move this complex apparatus represents a major challenge. Previous studies have given evidence of multiple cortical representations of hand movements including primary motor cortex, supplementary motor area, inferior area 6 and parietal cortex. These findings raise questions about the specificity of each of theses areas for the planning and control of distal movements. In the present study, the main focus was to investigate the properties of area F5 (rostral part of inferior area 6). Firstly, we investigated the specificity of the response of F5 neurons to two parameters, grip type and target orientation, during a delayed grasping task. This task was divided into well defined periods that allow the analysis of the neural response during different phases of the action, namely the object observation, the planning of the movement and the movement execution. Secondly, we investigated the representation of partial instruction information by separating the instruction of the orientation from the instruction of the grip type in distinct task epochs. Thirdly, a decoding simulation was performed in order to attest the possibility of decoding grasp movement intentions from area F5 for the possible application of a prosthetic hand control from brain signals. Specifically, we recorded neural activity in two macaque monkeys while they were presented with a handle that could be rotated in five possible orientations (upright, 25 and 50 degrees to the right or left). Simultaneously with the object presentation, a colored light instructed how the handle had to be grasped, either with a power or with a precision grip. Our results revealed that the grip type and the object orientation are both encoded in area F5. Their representation was similar during the instruction, but while the representation of object orientation was maintained constant, the representation of grip type significantly increased during the movement execution. These results suggest a major role of area F5 for shaping the fingers during grasping movement while its role for the positioning of the hand in the correct orientation might be reduced. Furthermore, cells with different tuning onset for grip type and orientation had been found. These different types of cells also showed differences in the simultaneous encoding of grip type and orientation. Moreover, the cue separation task revealed that the orientation representation was present in F5 even without a grip type instruction, but that the grip type was not encoded in F5 in the absence of the presentation of an object. Finally, the decoding simulation using a Bayesian classifier showed that grip type and orientation could both be decoded from area F5, but the performance was better for decoding the grip type than the orientation. In sum, the present thesis brings new insight to the representation of hand movement in area F5, in particular for the combined encoding of object orientation and grip type. It also reveals that hand movements can be decoded from higher order planning areas and that area F5 could be suitable for the implementation of a brain-machine interface for hand grasping which might have potential value for future applications in paralyzed patients." @default.
• W2775571816 created "2017-12-22" @default.
• W2775571816 creator A5044638174 @default.
• W2775571816 date "2009-01-01" @default.
• W2775571816 modified "2023-09-27" @default.
• W2775571816 title "Properties of macaque ventral premotor cortex during grasping" @default.
• W2775571816 doi "https://doi.org/10.5167/uzh-31996" @default.
• W2775571816 hasPublicationYear "2009" @default.
• W2775571816 type Work @default.
• W2775571816 sameAs 2775571816 @default.
• W2775571816 citedByCount "0" @default.
• W2775571816 crossrefType "dissertation" @default.
• W2775571816 hasAuthorship W2775571816A5044638174 @default.
• W2775571816 hasConcept C105702510 @default.
• W2775571816 hasConcept C107038049 @default.
• W2775571816 hasConcept C137813230 @default.
• W2775571816 hasConcept C138885662 @default.
• W2775571816 hasConcept C140530291 @default.
• W2775571816 hasConcept C154945302 @default.
• W2775571816 hasConcept C15744967 @default.
• W2775571816 hasConcept C162324750 @default.
• W2775571816 hasConcept C16345878 @default.
• W2775571816 hasConcept C169760540 @default.
• W2775571816 hasConcept C171268870 @default.
• W2775571816 hasConcept C187736073 @default.
• W2775571816 hasConcept C199360897 @default.
• W2775571816 hasConcept C24998067 @default.
• W2775571816 hasConcept C2524010 @default.
• W2775571816 hasConcept C2778373776 @default.
• W2775571816 hasConcept C2778950215 @default.
• W2775571816 hasConcept C2779226451 @default.
• W2775571816 hasConcept C2779534489 @default.
• W2775571816 hasConcept C2780226923 @default.
• W2775571816 hasConcept C2780451532 @default.
• W2775571816 hasConcept C2781238097 @default.
• W2775571816 hasConcept C2781300654 @default.
• W2775571816 hasConcept C33923547 @default.
• W2775571816 hasConcept C41008148 @default.
• W2775571816 hasConcept C46312422 @default.
• W2775571816 hasConcept C6757342 @default.
• W2775571816 hasConcept C86803240 @default.
• W2775571816 hasConceptScore W2775571816C105702510 @default.
• W2775571816 hasConceptScore W2775571816C107038049 @default.
• W2775571816 hasConceptScore W2775571816C137813230 @default.
• W2775571816 hasConceptScore W2775571816C138885662 @default.
• W2775571816 hasConceptScore W2775571816C140530291 @default.
• W2775571816 hasConceptScore W2775571816C154945302 @default.
• W2775571816 hasConceptScore W2775571816C15744967 @default.
• W2775571816 hasConceptScore W2775571816C162324750 @default.
• W2775571816 hasConceptScore W2775571816C16345878 @default.
• W2775571816 hasConceptScore W2775571816C169760540 @default.
• W2775571816 hasConceptScore W2775571816C171268870 @default.
• W2775571816 hasConceptScore W2775571816C187736073 @default.
• W2775571816 hasConceptScore W2775571816C199360897 @default.
• W2775571816 hasConceptScore W2775571816C24998067 @default.
• W2775571816 hasConceptScore W2775571816C2524010 @default.
• W2775571816 hasConceptScore W2775571816C2778373776 @default.
• W2775571816 hasConceptScore W2775571816C2778950215 @default.
• W2775571816 hasConceptScore W2775571816C2779226451 @default.
• W2775571816 hasConceptScore W2775571816C2779534489 @default.
• W2775571816 hasConceptScore W2775571816C2780226923 @default.
• W2775571816 hasConceptScore W2775571816C2780451532 @default.
• W2775571816 hasConceptScore W2775571816C2781238097 @default.
• W2775571816 hasConceptScore W2775571816C2781300654 @default.
• W2775571816 hasConceptScore W2775571816C33923547 @default.
• W2775571816 hasConceptScore W2775571816C41008148 @default.
• W2775571816 hasConceptScore W2775571816C46312422 @default.
• W2775571816 hasConceptScore W2775571816C6757342 @default.
• W2775571816 hasConceptScore W2775571816C86803240 @default.
• W2775571816 hasLocation W27755718161 @default.
• W2775571816 hasOpenAccess W2775571816 @default.
• W2775571816 hasPrimaryLocation W27755718161 @default.
• W2775571816 hasRelatedWork W1898093697 @default.
• W2775571816 hasRelatedWork W1974981452 @default.
• W2775571816 hasRelatedWork W1983779667 @default.
• W2775571816 hasRelatedWork W2005666783 @default.
• W2775571816 hasRelatedWork W2033751154 @default.
• W2775571816 hasRelatedWork W2057574932 @default.
• W2775571816 hasRelatedWork W2068533409 @default.
• W2775571816 hasRelatedWork W2091936554 @default.
• W2775571816 hasRelatedWork W2116087780 @default.
• W2775571816 hasRelatedWork W2149948293 @default.
• W2775571816 hasRelatedWork W2159375722 @default.
• W2775571816 hasRelatedWork W2244747209 @default.
• W2775571816 hasRelatedWork W2548825143 @default.
• W2775571816 hasRelatedWork W2891673628 @default.
• W2775571816 hasRelatedWork W2905072179 @default.
• W2775571816 hasRelatedWork W2992562431 @default.
• W2775571816 hasRelatedWork W3208521242 @default.
• W2775571816 hasRelatedWork W648021897 @default.
• W2775571816 hasRelatedWork W2186469572 @default.
• W2775571816 hasRelatedWork W2271832670 @default.
• W2775571816 isParatext "false" @default.
• W2775571816 isRetracted "false" @default.
• W2775571816 magId "2775571816" @default.
• W2775571816 workType "dissertation" @default.