FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2775678462> ?p ?o ?g. }

• W2775678462 endingPage "42" @default.
• W2775678462 startingPage "37" @default.
• W2775678462 abstract "Cervical cancer screening programs are switching from cytology-based screening to high-risk (hr) HPV testing. Only clinically validated tests should be used in clinical practice.To assess the clinical performance of the Roche Linear Array HPV genotyping test (Linear Array) within the VALGENT-3 framework.The VALGENT framework is designed for comprehensive comparison and clinical validation of HPV tests that have limited to extended genotyping capacity. The Linear Array enables type-specific detection of 37 HPV types. For the purpose of this study, Linear Array results were designated as positive only if one of the 13 hrHPV types also included in the Hybrid Capture 2 (HC2) was detected. The VALGENT-3 framework comprised 1600 samples obtained from Slovenian women (1300 sequential cases from routine cervical cancer screening enriched with 300 cytological abnormal samples). Sensitivity for cervical intraepithelial neoplasia of grade 2 or worse (CIN2+) (n=127) and specificity for <CIN2 (n=1216) were assessed for Linear Array and for HC2 and non-inferiority of Linear Array relative to HC2 was checked. In addition, the prevalence of separate hrHPV types in the screening population, as well as the concordance for presence of HPV16, HPV18 and other hrHPV types between Linear Array and the Abbott RealTime High Risk HPV test (RealTime) were assessed.The clinical sensitivity and specificity for CIN2+ of the Linear Array in the total study population was 97.6% (95% CI, 93.3-99.5%) and 91.7% (95% CI, 90.0-93.2%), respectively. The relative sensitivity and specificity of Linear Array vs HC2 was 1.02 [95% CI, 0.98-1.05, (p<0.001)] and 1.02 [95% CI, 1.01-1.03, (p<0.001)], respectively The overall prevalence of hrHPV using the Linear Array in the screening population was 10.5% (95% CI, 8.9-12.3%) with HPV16 and HPV18 detected in 2.3% and 0.9% of the samples, respectively. Excellent agreement for presence or absence of HPV16, HPV18 and other hrHPV between Linear Array and RealTime was observed.Linear Array showed similar sensitivity with higher specificity to detect CIN2+ compared to HC2. Detection of 13 hrHPV types with Linear Array fulfils the clinical accuracy requirements for primary cervical cancer screening." @default.
• W2775678462 created "2017-12-22" @default.
• W2775678462 creator A5051437283 @default.
• W2775678462 creator A5054984526 @default.
• W2775678462 creator A5055139463 @default.
• W2775678462 creator A5062790218 @default.
• W2775678462 date "2018-01-01" @default.
• W2775678462 modified "2023-10-14" @default.
• W2775678462 title "Assessment of the Roche Linear Array HPV Genotyping Test within the VALGENT framework" @default.
• W2775678462 cites W1904612675 @default.
• W2775678462 cites W1931876713 @default.
• W2775678462 cites W1983551020 @default.
• W2775678462 cites W1996007109 @default.
• W2775678462 cites W1998567451 @default.
• W2775678462 cites W2016496743 @default.
• W2775678462 cites W2022593871 @default.
• W2775678462 cites W2028548753 @default.
• W2775678462 cites W2048774841 @default.
• W2775678462 cites W2055327161 @default.
• W2775678462 cites W2070821176 @default.
• W2775678462 cites W2073215071 @default.
• W2775678462 cites W2079980269 @default.
• W2775678462 cites W2083125333 @default.
• W2775678462 cites W2084413241 @default.
• W2775678462 cites W2097111838 @default.
• W2775678462 cites W2100722838 @default.
• W2775678462 cites W2100775423 @default.
• W2775678462 cites W2101341125 @default.
• W2775678462 cites W2119977447 @default.
• W2775678462 cites W2129316684 @default.
• W2775678462 cites W2130297731 @default.
• W2775678462 cites W2133765716 @default.
• W2775678462 cites W2134674929 @default.
• W2775678462 cites W2140366237 @default.
• W2775678462 cites W2144175542 @default.
• W2775678462 cites W2156680734 @default.
• W2775678462 cites W2162404720 @default.
• W2775678462 cites W2171818897 @default.
• W2775678462 cites W2259021956 @default.
• W2775678462 cites W2272610599 @default.
• W2775678462 cites W2327814204 @default.
• W2775678462 cites W2401754048 @default.
• W2775678462 cites W2407334617 @default.
• W2775678462 cites W2462954037 @default.
• W2775678462 cites W2510482247 @default.
• W2775678462 cites W2762119256 @default.
• W2775678462 doi "https://doi.org/10.1016/j.jcv.2017.12.001" @default.
• W2775678462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29241150" @default.
• W2775678462 hasPublicationYear "2018" @default.
• W2775678462 type Work @default.
• W2775678462 sameAs 2775678462 @default.
• W2775678462 citedByCount "34" @default.
• W2775678462 countsByYear W27756784622018 @default.
• W2775678462 countsByYear W27756784622019 @default.
• W2775678462 countsByYear W27756784622020 @default.
• W2775678462 countsByYear W27756784622021 @default.
• W2775678462 countsByYear W27756784622022 @default.
• W2775678462 countsByYear W27756784622023 @default.
• W2775678462 crossrefType "journal-article" @default.
• W2775678462 hasAuthorship W2775678462A5051437283 @default.
• W2775678462 hasAuthorship W2775678462A5054984526 @default.
• W2775678462 hasAuthorship W2775678462A5055139463 @default.
• W2775678462 hasAuthorship W2775678462A5062790218 @default.
• W2775678462 hasConcept C104317684 @default.
• W2775678462 hasConcept C121608353 @default.
• W2775678462 hasConcept C126322002 @default.
• W2775678462 hasConcept C135763542 @default.
• W2775678462 hasConcept C142724271 @default.
• W2775678462 hasConcept C143998085 @default.
• W2775678462 hasConcept C160798450 @default.
• W2775678462 hasConcept C18823058 @default.
• W2775678462 hasConcept C2777343196 @default.
• W2775678462 hasConcept C2778220009 @default.
• W2775678462 hasConcept C2780647465 @default.
• W2775678462 hasConcept C2908647359 @default.
• W2775678462 hasConcept C29456083 @default.
• W2775678462 hasConcept C2993522905 @default.
• W2775678462 hasConcept C31467283 @default.
• W2775678462 hasConcept C54355233 @default.
• W2775678462 hasConcept C71924100 @default.
• W2775678462 hasConcept C86803240 @default.
• W2775678462 hasConcept C99454951 @default.
• W2775678462 hasConceptScore W2775678462C104317684 @default.
• W2775678462 hasConceptScore W2775678462C121608353 @default.
• W2775678462 hasConceptScore W2775678462C126322002 @default.
• W2775678462 hasConceptScore W2775678462C135763542 @default.
• W2775678462 hasConceptScore W2775678462C142724271 @default.
• W2775678462 hasConceptScore W2775678462C143998085 @default.
• W2775678462 hasConceptScore W2775678462C160798450 @default.
• W2775678462 hasConceptScore W2775678462C18823058 @default.
• W2775678462 hasConceptScore W2775678462C2777343196 @default.
• W2775678462 hasConceptScore W2775678462C2778220009 @default.
• W2775678462 hasConceptScore W2775678462C2780647465 @default.
• W2775678462 hasConceptScore W2775678462C2908647359 @default.
• W2775678462 hasConceptScore W2775678462C29456083 @default.
• W2775678462 hasConceptScore W2775678462C2993522905 @default.
• W2775678462 hasConceptScore W2775678462C31467283 @default.
• W2775678462 hasConceptScore W2775678462C54355233 @default.

• next