FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2776177791> ?p ?o ?g. }

• W2776177791 endingPage "742" @default.
• W2776177791 startingPage "728" @default.
• W2776177791 abstract "Mitochondria are essential organelles within the cell where most ATP is produced through oxidative phosphorylation (OXPHOS). A subset of the genes needed for this process are encoded by the mitochondrial DNA (mtDNA). One consequence of OXPHOS is the production of mitochondrial reactive oxygen species (ROS), whose role in mediating cellular damage, particularly in damaging mtDNA during ageing, has been controversial. There are subsets of neurons that appear to be more sensitive to ROS-induced damage, and mitochondrial dysfunction has been associated with several neurodegenerative disorders. In this review, we will discuss the current knowledge in the field of mtDNA and neurodegeneration, the debate about ROS as a pathological or beneficial contributor to neuronal function, bona fide mtDNA diseases, and insights from mouse models of mtDNA defects affecting the central nervous system." @default.
• W2776177791 created "2018-01-05" @default.
• W2776177791 creator A5021711176 @default.
• W2776177791 creator A5060561492 @default.
• W2776177791 date "2018-01-09" @default.
• W2776177791 modified "2023-10-17" @default.
• W2776177791 title "Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease" @default.
• W2776177791 cites W1505937405 @default.
• W2776177791 cites W1520910338 @default.
• W2776177791 cites W1521947818 @default.
• W2776177791 cites W1538214352 @default.
• W2776177791 cites W1561484646 @default.
• W2776177791 cites W1569716332 @default.
• W2776177791 cites W1575298809 @default.
• W2776177791 cites W1790985176 @default.
• W2776177791 cites W1827885532 @default.
• W2776177791 cites W1867176171 @default.
• W2776177791 cites W1874684536 @default.
• W2776177791 cites W1967253002 @default.
• W2776177791 cites W1972140717 @default.
• W2776177791 cites W1972533526 @default.
• W2776177791 cites W1973435863 @default.
• W2776177791 cites W1973851166 @default.
• W2776177791 cites W1976654687 @default.
• W2776177791 cites W1977069725 @default.
• W2776177791 cites W1977963038 @default.
• W2776177791 cites W1979369962 @default.
• W2776177791 cites W1980681204 @default.
• W2776177791 cites W1982733774 @default.
• W2776177791 cites W1983078193 @default.
• W2776177791 cites W1986219537 @default.
• W2776177791 cites W1987960916 @default.
• W2776177791 cites W1992477424 @default.
• W2776177791 cites W1993160420 @default.
• W2776177791 cites W1993503666 @default.
• W2776177791 cites W1995706959 @default.
• W2776177791 cites W1996813968 @default.
• W2776177791 cites W1998702457 @default.
• W2776177791 cites W2000730064 @default.
• W2776177791 cites W2002088854 @default.
• W2776177791 cites W2002198698 @default.
• W2776177791 cites W2002426440 @default.
• W2776177791 cites W2009041545 @default.
• W2776177791 cites W2015116743 @default.
• W2776177791 cites W2017347785 @default.
• W2776177791 cites W2018287672 @default.
• W2776177791 cites W2020293695 @default.
• W2776177791 cites W2023378584 @default.
• W2776177791 cites W2025656277 @default.
• W2776177791 cites W2026525843 @default.
• W2776177791 cites W2026686875 @default.
• W2776177791 cites W2029919775 @default.
• W2776177791 cites W2030396508 @default.
• W2776177791 cites W2030865407 @default.
• W2776177791 cites W2033793342 @default.
• W2776177791 cites W2033832481 @default.
• W2776177791 cites W2035564874 @default.
• W2776177791 cites W2035636870 @default.
• W2776177791 cites W2035869371 @default.
• W2776177791 cites W2036074567 @default.
• W2776177791 cites W2038440451 @default.
• W2776177791 cites W2040175583 @default.
• W2776177791 cites W2040209654 @default.
• W2776177791 cites W2040987236 @default.
• W2776177791 cites W2044897807 @default.
• W2776177791 cites W2046847750 @default.
• W2776177791 cites W2052815889 @default.
• W2776177791 cites W2053040219 @default.
• W2776177791 cites W2054511417 @default.
• W2776177791 cites W2055513768 @default.
• W2776177791 cites W2056015556 @default.
• W2776177791 cites W2056644558 @default.
• W2776177791 cites W2058106189 @default.
• W2776177791 cites W2060061148 @default.
• W2776177791 cites W2062834612 @default.
• W2776177791 cites W2068337326 @default.
• W2776177791 cites W2068469769 @default.
• W2776177791 cites W2075291968 @default.
• W2776177791 cites W2076598575 @default.
• W2776177791 cites W2077414996 @default.
• W2776177791 cites W2078478142 @default.
• W2776177791 cites W2084621494 @default.
• W2776177791 cites W2085396235 @default.
• W2776177791 cites W2085525271 @default.
• W2776177791 cites W2087080349 @default.
• W2776177791 cites W2092011963 @default.
• W2776177791 cites W2095626761 @default.
• W2776177791 cites W2097114048 @default.
• W2776177791 cites W2097732206 @default.
• W2776177791 cites W2100297462 @default.
• W2776177791 cites W2103451241 @default.
• W2776177791 cites W2103538836 @default.
• W2776177791 cites W2104198237 @default.
• W2776177791 cites W2105744930 @default.
• W2776177791 cites W2106396251 @default.
• W2776177791 cites W2107612815 @default.
• W2776177791 cites W2108697350 @default.
• W2776177791 cites W2109291482 @default.

• next