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- W2776427746 abstract "By condensing the available 4-formilpirazol-3-carboxylic acid with tiosemicarbazid in boiling acetic acid synthesized 4-pyrazolyl-tiosemikarbazons with high (76-91%) obtaining, the composition and structure of which are confirmed by the results of elemental analysis, and measurement of hromatomas, IR and NMR 1H spectra. It was established that the synthesized 4-pyrazolyl tiosemikarbazons show moderate antimicrobial activity and a broad spectrum of antimicrobial activity. This shows that derivatives 4-pyrazolyl tiosemikarbazons show slightly higher antifungal effect compared with the antibiotic - the minimum fungicidal concentrations of these compounds were lower than their minimum bactericidal concentration at 2-4. The results indicate that compounds of this type are attractive synthetic blocks for cyclic bioperspectives pyrazole derivatives." @default.
- W2776427746 created "2018-01-05" @default.
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- W2776427746 date "2017-12-27" @default.
- W2776427746 modified "2023-09-25" @default.
- W2776427746 title "SYNTHESIS AND STUDY OF ANTIMICROBIAL PROPERTIES (3-ARYL-1-PHENYL-1H-PYRAZOL) -4-CARBALDEHYDE TIOSEMIKARBAZON" @default.
- W2776427746 doi "https://doi.org/10.24061/1727-4338.xvi.1.59.2017.12" @default.
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