Matches in SemOpenAlex for { <https://semopenalex.org/work/W2776595861> ?p ?o ?g. }
- W2776595861 abstract "Porphyra yezoensis is a red alga consumed mainly in Korea, Japan, and China for food. This study researches the immunological effect of pepsin extract of P. yezoensis (PPEE) on murine splenocytes.PPEE was not toxic on murine splenocytes and dramatically increased the proliferation of splenocytes compared with untreated control. Flow cytometry assay performed to sum up the effect of PPEE (31.3 and 62.5 µg mL-1 ) on major immune cells revealed that PPEE had no effect on the function of CD3e+ CD4+ T-helper cells, CD3e+ CD8+ T-cytotoxic cells, or CD44+ CD62L- effector T cells in splenocytes compared with untreated control. More importantly, CD45+ CD11b+ macrophage and dendritic cell populations and Ly-6C+ Ly-6G+ macrophages/monocytes in splenocytes were activated by PPEE treatment compared with untreated control. Further experiments showed that PPEE treatment increased the secretion of macrophage-derived cytokines such as interleukin-1β, tumor necrosis factor-α, and interleukin-12, and macrophage-activating cytokines interferon-γ and interleukin-10 compared with untreated control.Taken together, these results suggest that PPEE has an immune stimulatory effect on macrophages, dendritic cells, and memory T cells. This property signifies the potential medicinal value of PPEE in clinical implications for immune-compromised diseases. © 2017 Society of Chemical Industry." @default.
- W2776595861 created "2018-01-05" @default.
- W2776595861 creator A5005044285 @default.
- W2776595861 creator A5005895266 @default.
- W2776595861 creator A5009446618 @default.
- W2776595861 creator A5011649304 @default.
- W2776595861 creator A5040505261 @default.
- W2776595861 creator A5042551224 @default.
- W2776595861 creator A5059111599 @default.
- W2776595861 creator A5073002854 @default.
- W2776595861 date "2018-02-28" @default.
- W2776595861 modified "2023-09-23" @default.
- W2776595861 title "Immunostimulatory effect of pepsin enzymatic extract fromPorphyra yezoensison murine splenocytes" @default.
- W2776595861 cites W1183372573 @default.
- W2776595861 cites W161808489 @default.
- W2776595861 cites W1973834397 @default.
- W2776595861 cites W1977312866 @default.
- W2776595861 cites W1988659689 @default.
- W2776595861 cites W1997465952 @default.
- W2776595861 cites W2004163860 @default.
- W2776595861 cites W2004238073 @default.
- W2776595861 cites W2013069706 @default.
- W2776595861 cites W2027032537 @default.
- W2776595861 cites W2043784314 @default.
- W2776595861 cites W2052149521 @default.
- W2776595861 cites W2054472394 @default.
- W2776595861 cites W2058507546 @default.
- W2776595861 cites W2069535526 @default.
- W2776595861 cites W2081374651 @default.
- W2776595861 cites W2083084591 @default.
- W2776595861 cites W2092947764 @default.
- W2776595861 cites W2094190503 @default.
- W2776595861 cites W2101957891 @default.
- W2776595861 cites W2106684817 @default.
- W2776595861 cites W2118205675 @default.
- W2776595861 cites W2130594874 @default.
- W2776595861 cites W2146313292 @default.
- W2776595861 cites W2166529622 @default.
- W2776595861 cites W2176134716 @default.
- W2776595861 cites W2276012049 @default.
- W2776595861 cites W2301044272 @default.
- W2776595861 cites W2376936448 @default.
- W2776595861 cites W2467677013 @default.
- W2776595861 cites W2473710848 @default.
- W2776595861 cites W4245248161 @default.
- W2776595861 cites W571091722 @default.
- W2776595861 cites W966863505 @default.
- W2776595861 doi "https://doi.org/10.1002/jsfa.8851" @default.
- W2776595861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29280143" @default.
- W2776595861 hasPublicationYear "2018" @default.
- W2776595861 type Work @default.
- W2776595861 sameAs 2776595861 @default.
- W2776595861 citedByCount "5" @default.
- W2776595861 countsByYear W27765958612019 @default.
- W2776595861 countsByYear W27765958612020 @default.
- W2776595861 countsByYear W27765958612021 @default.
- W2776595861 crossrefType "journal-article" @default.
- W2776595861 hasAuthorship W2776595861A5005044285 @default.
- W2776595861 hasAuthorship W2776595861A5005895266 @default.
- W2776595861 hasAuthorship W2776595861A5009446618 @default.
- W2776595861 hasAuthorship W2776595861A5011649304 @default.
- W2776595861 hasAuthorship W2776595861A5040505261 @default.
- W2776595861 hasAuthorship W2776595861A5042551224 @default.
- W2776595861 hasAuthorship W2776595861A5059111599 @default.
- W2776595861 hasAuthorship W2776595861A5073002854 @default.
- W2776595861 hasConcept C153911025 @default.
- W2776595861 hasConcept C16311235 @default.
- W2776595861 hasConcept C167672396 @default.
- W2776595861 hasConcept C17991360 @default.
- W2776595861 hasConcept C181199279 @default.
- W2776595861 hasConcept C185592680 @default.
- W2776595861 hasConcept C189976730 @default.
- W2776595861 hasConcept C202751555 @default.
- W2776595861 hasConcept C203014093 @default.
- W2776595861 hasConcept C2779244956 @default.
- W2776595861 hasConcept C553184892 @default.
- W2776595861 hasConcept C55493867 @default.
- W2776595861 hasConcept C86803240 @default.
- W2776595861 hasConcept C8891405 @default.
- W2776595861 hasConceptScore W2776595861C153911025 @default.
- W2776595861 hasConceptScore W2776595861C16311235 @default.
- W2776595861 hasConceptScore W2776595861C167672396 @default.
- W2776595861 hasConceptScore W2776595861C17991360 @default.
- W2776595861 hasConceptScore W2776595861C181199279 @default.
- W2776595861 hasConceptScore W2776595861C185592680 @default.
- W2776595861 hasConceptScore W2776595861C189976730 @default.
- W2776595861 hasConceptScore W2776595861C202751555 @default.
- W2776595861 hasConceptScore W2776595861C203014093 @default.
- W2776595861 hasConceptScore W2776595861C2779244956 @default.
- W2776595861 hasConceptScore W2776595861C553184892 @default.
- W2776595861 hasConceptScore W2776595861C55493867 @default.
- W2776595861 hasConceptScore W2776595861C86803240 @default.
- W2776595861 hasConceptScore W2776595861C8891405 @default.
- W2776595861 hasLocation W27765958611 @default.
- W2776595861 hasLocation W27765958612 @default.
- W2776595861 hasOpenAccess W2776595861 @default.
- W2776595861 hasPrimaryLocation W27765958611 @default.
- W2776595861 hasRelatedWork W1984968305 @default.
- W2776595861 hasRelatedWork W2062888014 @default.
- W2776595861 hasRelatedWork W2142928351 @default.