Matches in SemOpenAlex for { <https://semopenalex.org/work/W2776857198> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2776857198 endingPage "148" @default.
- W2776857198 startingPage "141" @default.
- W2776857198 abstract "Phytochemical investigation of the CH2Cl2/MeOH (1:1) extract of the roots of Lannea rivae (Chiov) Sacleux (Anacardiaceae) led to the isolation of a new alkenyl cyclohexenone derivative: (4R,6S)-4,6-dihydroxy-6-((Z)-nonadec-14′-en-1-yl)cyclohex-2-en-1-one (1), and a new alkenyl cyclohexanol derivative: (2S*,4R*,5S*)-2,4,5-trihydroxy-2-((Z)-nonadec-14′-en-1-yl)cyclohexanone (2) along with four known compounds, namely epicatechin gallate, taraxerol, taraxerone and β-sitosterol; while the stem bark afforded two known compounds, daucosterol and lupeol. Similar investigation of the roots of Lannea schweinfurthii (Engl.) Engl. led to the isolation of four known compounds: 3-((E)-nonadec-16′-enyl)phenol, 1-((E)-heptadec-14′-enyl)cyclohex-4-ene-1,3-diol, catechin, and 1-((E)-pentadec-12′-enyl)cyclohex-4-ene-1,3-diol. The structures of the isolated compounds were determined by NMR spectroscopy and mass spectrometry. The absolute configuration of compound 1 was established by quantum chemical ECD calculations. In an antibacterial activity assay using the microbroth kinetic method, compound 1 showed moderate activity against Escherichia coli while compound 2 exhibited moderate activity against Staphylococcus aureus. Compound 1 also showed moderate activity against E. coli using the disc diffusion method. The roots extract of L. rivae was notably cytotoxic against both the DU-145 prostate cancer cell line and the Vero mammalian cell line (CC50 = 5.24 and 5.20 μg/mL, respectively). Compound 1 was also strongly cytotoxic against the DU-145 cell line (CC50 = 0.55 μg/mL) but showed no observable cytotoxicity (CC50 > 100 μg/mL) against the Vero cell line. The roots extract of L. rivae and L. schweinfurthii, epicatechin gallate as well as compound 1 exhibited inhibition of carageenan-induced inflammation." @default.
- W2776857198 created "2018-01-05" @default.
- W2776857198 creator A5024247648 @default.
- W2776857198 creator A5036349468 @default.
- W2776857198 creator A5038140719 @default.
- W2776857198 creator A5047765243 @default.
- W2776857198 creator A5061350711 @default.
- W2776857198 creator A5074009285 @default.
- W2776857198 creator A5079661426 @default.
- W2776857198 date "2018-02-01" @default.
- W2776857198 modified "2023-09-24" @default.
- W2776857198 title "Alkenyl cyclohexanone derivatives from Lannea rivae and Lannea schweinfurthii" @default.
- W2776857198 cites W1781812304 @default.
- W2776857198 cites W1886762948 @default.
- W2776857198 cites W1968549481 @default.
- W2776857198 cites W1982873936 @default.
- W2776857198 cites W1986503394 @default.
- W2776857198 cites W1997432357 @default.
- W2776857198 cites W1998935467 @default.
- W2776857198 cites W2017786293 @default.
- W2776857198 cites W2019723564 @default.
- W2776857198 cites W2026969368 @default.
- W2776857198 cites W2029421734 @default.
- W2776857198 cites W2040455666 @default.
- W2776857198 cites W2052207251 @default.
- W2776857198 cites W2062133606 @default.
- W2776857198 cites W2062166596 @default.
- W2776857198 cites W2063170038 @default.
- W2776857198 cites W2068228867 @default.
- W2776857198 cites W2078067389 @default.
- W2776857198 cites W2079151619 @default.
- W2776857198 cites W2082876306 @default.
- W2776857198 cites W2083348480 @default.
- W2776857198 cites W2087601544 @default.
- W2776857198 cites W2093779816 @default.
- W2776857198 cites W2095919199 @default.
- W2776857198 cites W2103517584 @default.
- W2776857198 cites W2143981217 @default.
- W2776857198 cites W2152488337 @default.
- W2776857198 cites W2164325425 @default.
- W2776857198 cites W2269616377 @default.
- W2776857198 cites W2414040061 @default.
- W2776857198 cites W2497497879 @default.
- W2776857198 cites W2511695285 @default.
- W2776857198 doi "https://doi.org/10.1016/j.phytol.2017.12.001" @default.
- W2776857198 hasPublicationYear "2018" @default.
- W2776857198 type Work @default.
- W2776857198 sameAs 2776857198 @default.
- W2776857198 citedByCount "11" @default.
- W2776857198 countsByYear W27768571982018 @default.
- W2776857198 countsByYear W27768571982019 @default.
- W2776857198 countsByYear W27768571982021 @default.
- W2776857198 countsByYear W27768571982022 @default.
- W2776857198 countsByYear W27768571982023 @default.
- W2776857198 crossrefType "journal-article" @default.
- W2776857198 hasAuthorship W2776857198A5024247648 @default.
- W2776857198 hasAuthorship W2776857198A5036349468 @default.
- W2776857198 hasAuthorship W2776857198A5038140719 @default.
- W2776857198 hasAuthorship W2776857198A5047765243 @default.
- W2776857198 hasAuthorship W2776857198A5061350711 @default.
- W2776857198 hasAuthorship W2776857198A5074009285 @default.
- W2776857198 hasAuthorship W2776857198A5079661426 @default.
- W2776857198 hasConcept C178790620 @default.
- W2776857198 hasConcept C185592680 @default.
- W2776857198 hasConcept C195475562 @default.
- W2776857198 hasConcept C2779782153 @default.
- W2776857198 hasConcept C55493867 @default.
- W2776857198 hasConcept C556039675 @default.
- W2776857198 hasConcept C71240020 @default.
- W2776857198 hasConcept C71924100 @default.
- W2776857198 hasConceptScore W2776857198C178790620 @default.
- W2776857198 hasConceptScore W2776857198C185592680 @default.
- W2776857198 hasConceptScore W2776857198C195475562 @default.
- W2776857198 hasConceptScore W2776857198C2779782153 @default.
- W2776857198 hasConceptScore W2776857198C55493867 @default.
- W2776857198 hasConceptScore W2776857198C556039675 @default.
- W2776857198 hasConceptScore W2776857198C71240020 @default.
- W2776857198 hasConceptScore W2776857198C71924100 @default.
- W2776857198 hasLocation W27768571981 @default.
- W2776857198 hasOpenAccess W2776857198 @default.
- W2776857198 hasPrimaryLocation W27768571981 @default.
- W2776857198 hasRelatedWork W2009824470 @default.
- W2776857198 hasRelatedWork W2047606871 @default.
- W2776857198 hasRelatedWork W2182629686 @default.
- W2776857198 hasRelatedWork W2887667931 @default.
- W2776857198 hasRelatedWork W2981010088 @default.
- W2776857198 hasRelatedWork W3127658593 @default.
- W2776857198 hasRelatedWork W3145259895 @default.
- W2776857198 hasRelatedWork W3191042775 @default.
- W2776857198 hasRelatedWork W3210623336 @default.
- W2776857198 hasRelatedWork W4200092947 @default.
- W2776857198 hasVolume "23" @default.
- W2776857198 isParatext "false" @default.
- W2776857198 isRetracted "false" @default.
- W2776857198 magId "2776857198" @default.
- W2776857198 workType "article" @default.