Matches in SemOpenAlex for { <https://semopenalex.org/work/W2776954579> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2776954579 endingPage "550" @default.
- W2776954579 startingPage "544" @default.
- W2776954579 abstract "Abstract Deoxypodophyllotoxin is present in the roots of Anthriscus sylvestris. This compound is cytotoxic on its own, but it can also be converted into podophyllotoxin, which is in high demand as a precursor for the important anticancer drugs etoposide and teniposide. In this study, deoxypodophyllotoxin is extracted from A. sylvestris roots by supercritical carbon dioxide extraction. The process is simple and scalable. The supercritical carbon dioxide method extracts 75 – 80% of the total deoxypodophyllotoxin content, which is comparable to a single extraction by traditional Soxhlet. However, less polar components are extracted. The activity of the supercritical carbon dioxide extract containing deoxypodophyllotoxin was assessed by demonstrating that the extract arrests A549 and HeLa cells in the G2/M phase of the cell cycle. We conclude that biologically active deoxypodophyllotoxin can be extracted from A. sylvestris by supercritical carbon dioxide extraction. The method is solvent free and more sustainable compared to traditional methods." @default.
- W2776954579 created "2018-01-05" @default.
- W2776954579 creator A5006246608 @default.
- W2776954579 creator A5010639861 @default.
- W2776954579 creator A5055109477 @default.
- W2776954579 creator A5084961817 @default.
- W2776954579 date "2017-12-18" @default.
- W2776954579 modified "2023-09-27" @default.
- W2776954579 title "Cytotoxic Deoxypodophyllotoxin Can Be Extracted in High Purity from Anthriscus sylvestris Roots by Supercritical Carbon Dioxide" @default.
- W2776954579 cites W1558985750 @default.
- W2776954579 cites W1598395113 @default.
- W2776954579 cites W1830282417 @default.
- W2776954579 cites W1963861448 @default.
- W2776954579 cites W1965751301 @default.
- W2776954579 cites W1975823826 @default.
- W2776954579 cites W1983138420 @default.
- W2776954579 cites W1989753305 @default.
- W2776954579 cites W2027468585 @default.
- W2776954579 cites W2044910245 @default.
- W2776954579 cites W2050679694 @default.
- W2776954579 cites W2068178400 @default.
- W2776954579 cites W2084054772 @default.
- W2776954579 cites W2084734547 @default.
- W2776954579 cites W2084971501 @default.
- W2776954579 cites W2086143289 @default.
- W2776954579 cites W2138344872 @default.
- W2776954579 cites W2139287008 @default.
- W2776954579 cites W2145093524 @default.
- W2776954579 cites W2150926819 @default.
- W2776954579 cites W2319799520 @default.
- W2776954579 cites W2351455396 @default.
- W2776954579 cites W2410476859 @default.
- W2776954579 cites W2730116579 @default.
- W2776954579 cites W2979399191 @default.
- W2776954579 cites W959142586 @default.
- W2776954579 doi "https://doi.org/10.1055/s-0043-123938" @default.
- W2776954579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29253908" @default.
- W2776954579 hasPublicationYear "2017" @default.
- W2776954579 type Work @default.
- W2776954579 sameAs 2776954579 @default.
- W2776954579 citedByCount "2" @default.
- W2776954579 countsByYear W27769545792020 @default.
- W2776954579 countsByYear W27769545792023 @default.
- W2776954579 crossrefType "journal-article" @default.
- W2776954579 hasAuthorship W2776954579A5006246608 @default.
- W2776954579 hasAuthorship W2776954579A5010639861 @default.
- W2776954579 hasAuthorship W2776954579A5055109477 @default.
- W2776954579 hasAuthorship W2776954579A5084961817 @default.
- W2776954579 hasBestOaLocation W27769545791 @default.
- W2776954579 hasConcept C118419359 @default.
- W2776954579 hasConcept C134458231 @default.
- W2776954579 hasConcept C178790620 @default.
- W2776954579 hasConcept C185592680 @default.
- W2776954579 hasConcept C199919908 @default.
- W2776954579 hasConcept C2776694085 @default.
- W2776954579 hasConcept C2778119113 @default.
- W2776954579 hasConcept C2778143360 @default.
- W2776954579 hasConcept C43617362 @default.
- W2776954579 hasConcept C4725764 @default.
- W2776954579 hasConcept C530467964 @default.
- W2776954579 hasConcept C54355233 @default.
- W2776954579 hasConcept C86803240 @default.
- W2776954579 hasConceptScore W2776954579C118419359 @default.
- W2776954579 hasConceptScore W2776954579C134458231 @default.
- W2776954579 hasConceptScore W2776954579C178790620 @default.
- W2776954579 hasConceptScore W2776954579C185592680 @default.
- W2776954579 hasConceptScore W2776954579C199919908 @default.
- W2776954579 hasConceptScore W2776954579C2776694085 @default.
- W2776954579 hasConceptScore W2776954579C2778119113 @default.
- W2776954579 hasConceptScore W2776954579C2778143360 @default.
- W2776954579 hasConceptScore W2776954579C43617362 @default.
- W2776954579 hasConceptScore W2776954579C4725764 @default.
- W2776954579 hasConceptScore W2776954579C530467964 @default.
- W2776954579 hasConceptScore W2776954579C54355233 @default.
- W2776954579 hasConceptScore W2776954579C86803240 @default.
- W2776954579 hasIssue "08" @default.
- W2776954579 hasLocation W27769545791 @default.
- W2776954579 hasLocation W27769545792 @default.
- W2776954579 hasLocation W27769545793 @default.
- W2776954579 hasOpenAccess W2776954579 @default.
- W2776954579 hasPrimaryLocation W27769545791 @default.
- W2776954579 hasRelatedWork W1527847607 @default.
- W2776954579 hasRelatedWork W1980355529 @default.
- W2776954579 hasRelatedWork W2001282418 @default.
- W2776954579 hasRelatedWork W2057852914 @default.
- W2776954579 hasRelatedWork W2063578829 @default.
- W2776954579 hasRelatedWork W2070464846 @default.
- W2776954579 hasRelatedWork W2313887078 @default.
- W2776954579 hasRelatedWork W2391052580 @default.
- W2776954579 hasRelatedWork W2594505097 @default.
- W2776954579 hasRelatedWork W3136474940 @default.
- W2776954579 hasVolume "84" @default.
- W2776954579 isParatext "false" @default.
- W2776954579 isRetracted "false" @default.
- W2776954579 magId "2776954579" @default.
- W2776954579 workType "article" @default.