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- W2777009493 abstract "In this issue of Molecular Therapy, two articles1,2 and the related Letter to the Editor3 provide extensive data on replication-competent retrovirus (RCR) and replication-competent lentivirus (RCL) monitoring in T cells genetically modified with retroviral or lentiviral vectors and in patient follow-up samples; no evidence for RCR or RCL has yet been found. These and previous studies4,5 argue that T cell products from an RCR- or RCL-negative vector lot need no longer be routinely subjected to this expensive and burdensome testing and that patient follow-up samples can be archived rather than tested." @default.
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- W2777009493 date "2018-01-01" @default.
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- W2777009493 title "Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy" @default.
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- W2777009493 doi "https://doi.org/10.1016/j.ymthe.2017.12.004" @default.
- W2777009493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5763151" @default.
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