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- W2777127952 abstract "In this issue of Pediatrics , Mendle et al1 examine the longitudinal connections between menarchal age and depression symptoms and antisocial behavior. The study was done by using data from Add Health, a well-known, nationally representative data set that reported on various health behaviors and outcomes from adolescence to adulthood (final age was late 20s or early 30s). The researchers found that the earlier the participants experienced menarche, the more likely they were to have depression symptoms and antisocial behavior in adolescence. In addition, these outcomes persisted into adulthood, 13 years later. A large body of literature has described the link between early puberty and behavioral concerns, and this study extends that evidence into adult behavioral outcomes.Several biologic mechanisms may contribute to early puberty’s relationship with depressive symptoms. In women, estradiol may modulate the production of serotonin receptors; this potentially influences mood … Address correspondence to Ellen Selkie, MD, MPH, Division of Adolescent Medicine, Department of Pediatrics, University of Michigan, 300 N Ingalls St, Room 6E07, Ann Arbor, MI 48109. E-mail: eselkie{at}umich.edu" @default.
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- W2777127952 date "2017-12-26" @default.
- W2777127952 modified "2023-09-23" @default.
- W2777127952 title "When Age-Based Guidance Is Not Enough: The Problem of Early Puberty" @default.
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- W2777127952 doi "https://doi.org/10.1542/peds.2017-3460" @default.
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