FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2777167510> ?p ?o ?g. }

• W2777167510 abstract "Fungal rhinosinusitis (FRS) is commonly caused by various Aspergillus species (spp) and Mucorales fungi, and the treatment and prognosis of cases differ depending on the causative fungus. The present study describes a novel immunohistochemical method that has high sensitivity and specificity for distinguishing between these two types of fungi in patients with FRS. Three groups were included in the study. Group A included formalin‑fixed paraffin‑embedded blocks of 51 nasal tissue specimens of patients with FRS (27 Aspergillus spp and 24 Mucorales) that were continuously obtained from the Department of Pathology of Tongren Hospital in Beijing as the experimental group and 34 cultures (26 Aspergillus spp and 8 Mucorales) of FRS that were randomly selected from the bacterial laboratory of Tongren Hospital in Beijing to verify the staining results of the paraffin‑embedded blocks. Formalin‑fixed paraffin‑embedded blocks of 10 esophageal cancer specimens were included in Group B as the positive control group. All specimens in Groups A and B were stained with interferon‑γ (IFN‑γ) antibody. Group C consisted of the same specimens as described in Group A, however, when performing the immunohistochemical assay, IFN‑γ antibody was replaced by PBS and this served as the negative control group. The differences in IFN‑γ immunohistochemical staining between Aspergillus spp and Mucorales were analyzed. Staining of IFN‑γ in paraffin‑embedded samples was positive in 92.6% (25/27) of specimens in which Aspergillus spp were the causative pathogen, which was significantly higher compared with specimens in which Mucorales was causative (P<0.001), with only 4.2% (1/24) of specimens staining positive for IFN‑γ. Immunohistochemical staining of cell cultures was 100% positive for Aspergillus spp, whereas all Mucorales were negative. Thus, the results of the current study indicated that IFN‑γ antibody immunohistochemical staining may be used as a novel diagnostic tool to distinguish between Aspergillus spp and Mucorales when identifying the causative agent in FRS, providing a useful supplementary test to the current immunohistochemical methods in the clinical diagnosis of FRS." @default.
• W2777167510 created "2018-01-05" @default.
• W2777167510 creator A5000485121 @default.
• W2777167510 creator A5008532305 @default.
• W2777167510 creator A5020919204 @default.
• W2777167510 creator A5022440919 @default.
• W2777167510 creator A5023312754 @default.
• W2777167510 creator A5024162379 @default.
• W2777167510 creator A5024220393 @default.
• W2777167510 creator A5042329149 @default.
• W2777167510 creator A5058850886 @default.
• W2777167510 creator A5061956458 @default.
• W2777167510 creator A5063391448 @default.
• W2777167510 creator A5066096874 @default.
• W2777167510 creator A5067812854 @default.
• W2777167510 creator A5068846668 @default.
• W2777167510 date "2017-12-27" @default.
• W2777167510 modified "2023-09-29" @default.
• W2777167510 title "Using IFN-γ antibodies to identify the pathogens of fungal rhinosinusitis: A novel immunohistochemical approach" @default.
• W2777167510 cites W1592214152 @default.
• W2777167510 cites W1969663464 @default.
• W2777167510 cites W1978569335 @default.
• W2777167510 cites W2001403314 @default.
• W2777167510 cites W2017378923 @default.
• W2777167510 cites W2041927010 @default.
• W2777167510 cites W2051226697 @default.
• W2777167510 cites W2058271592 @default.
• W2777167510 cites W2061442098 @default.
• W2777167510 cites W2069285341 @default.
• W2777167510 cites W2073350198 @default.
• W2777167510 cites W2086710290 @default.
• W2777167510 cites W2091180725 @default.
• W2777167510 cites W2094461599 @default.
• W2777167510 cites W2101052228 @default.
• W2777167510 cites W2102009630 @default.
• W2777167510 cites W2111550372 @default.
• W2777167510 cites W2150014287 @default.
• W2777167510 cites W2163438457 @default.
• W2777167510 cites W2167017590 @default.
• W2777167510 doi "https://doi.org/10.3892/mmr.2017.8359" @default.
• W2777167510 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5802167" @default.
• W2777167510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29286163" @default.
• W2777167510 hasPublicationYear "2017" @default.
• W2777167510 type Work @default.
• W2777167510 sameAs 2777167510 @default.
• W2777167510 citedByCount "0" @default.
• W2777167510 crossrefType "journal-article" @default.
• W2777167510 hasAuthorship W2777167510A5000485121 @default.
• W2777167510 hasAuthorship W2777167510A5008532305 @default.
• W2777167510 hasAuthorship W2777167510A5020919204 @default.
• W2777167510 hasAuthorship W2777167510A5022440919 @default.
• W2777167510 hasAuthorship W2777167510A5023312754 @default.
• W2777167510 hasAuthorship W2777167510A5024162379 @default.
• W2777167510 hasAuthorship W2777167510A5024220393 @default.
• W2777167510 hasAuthorship W2777167510A5042329149 @default.
• W2777167510 hasAuthorship W2777167510A5058850886 @default.
• W2777167510 hasAuthorship W2777167510A5061956458 @default.
• W2777167510 hasAuthorship W2777167510A5063391448 @default.
• W2777167510 hasAuthorship W2777167510A5066096874 @default.
• W2777167510 hasAuthorship W2777167510A5067812854 @default.
• W2777167510 hasAuthorship W2777167510A5068846668 @default.
• W2777167510 hasBestOaLocation W27771675101 @default.
• W2777167510 hasConcept C142724271 @default.
• W2777167510 hasConcept C159654299 @default.
• W2777167510 hasConcept C203014093 @default.
• W2777167510 hasConcept C204232928 @default.
• W2777167510 hasConcept C2777292849 @default.
• W2777167510 hasConcept C2779175654 @default.
• W2777167510 hasConcept C2779696498 @default.
• W2777167510 hasConcept C71924100 @default.
• W2777167510 hasConcept C74864618 @default.
• W2777167510 hasConcept C86803240 @default.
• W2777167510 hasConcept C89423630 @default.
• W2777167510 hasConceptScore W2777167510C142724271 @default.
• W2777167510 hasConceptScore W2777167510C159654299 @default.
• W2777167510 hasConceptScore W2777167510C203014093 @default.
• W2777167510 hasConceptScore W2777167510C204232928 @default.
• W2777167510 hasConceptScore W2777167510C2777292849 @default.
• W2777167510 hasConceptScore W2777167510C2779175654 @default.
• W2777167510 hasConceptScore W2777167510C2779696498 @default.
• W2777167510 hasConceptScore W2777167510C71924100 @default.
• W2777167510 hasConceptScore W2777167510C74864618 @default.
• W2777167510 hasConceptScore W2777167510C86803240 @default.
• W2777167510 hasConceptScore W2777167510C89423630 @default.
• W2777167510 hasLocation W27771675101 @default.
• W2777167510 hasLocation W27771675102 @default.
• W2777167510 hasLocation W27771675103 @default.
• W2777167510 hasLocation W27771675104 @default.
• W2777167510 hasOpenAccess W2777167510 @default.
• W2777167510 hasPrimaryLocation W27771675101 @default.
• W2777167510 hasRelatedWork W1510635029 @default.
• W2777167510 hasRelatedWork W1514510306 @default.
• W2777167510 hasRelatedWork W1979115929 @default.
• W2777167510 hasRelatedWork W2001912479 @default.
• W2777167510 hasRelatedWork W2002981582 @default.
• W2777167510 hasRelatedWork W2023238293 @default.
• W2777167510 hasRelatedWork W2067272592 @default.
• W2777167510 hasRelatedWork W2071039804 @default.
• W2777167510 hasRelatedWork W2076748515 @default.
• W2777167510 hasRelatedWork W2157664212 @default.

• next