FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2777309499> ?p ?o ?g. }

• W2777309499 abstract "Astroviruses are important drivers of viral gastroenteritis but remain understudied in community settings and low- and middle-income countries. We present data from 8 countries with high prevalence of diarrhea and undernutrition to describe astrovirus epidemiology and assess evidence for protective immunity among children 0 to 2 years of age.We used 25 898 surveillance stools and 7077 diarrheal stools contributed by 2082 children for enteropathogen testing, and longitudinal statistical analysis to describe incidence, risk factors, and protective immunity.Thirty-five percent of children experienced astrovirus infections. Prevalence in diarrheal stools was 5.6%, and severity exceeded all enteropathogens except rotavirus. Incidence of infection and diarrhea were 2.12 and 0.88 episodes per 100 child-months, respectively. Children with astrovirus infection had 2.30 times the odds of experiencing diarrhea after adjustment for covariates (95% confidence interval [CI], 2.01-2.62; P < .001). Undernutrition was a risk factor: odds of infection and diarrhea were reduced by 10% and 13%, respectively, per increase in length-for-age z score (infection: odds ratio, 0.90 [95% CI, 0.85-0.96]; P < .001; diarrhea: odds ratio, 0.87 [95% CI, 0.79-0.96]; P = .006). Some evidence of protective immunity to infection was detected (hazard ratio, 0.84 [95% CI, 0.71-1.00], P = .052), although this was heterogeneous between sites and significant in India and Peru.Astrovirus is an overlooked cause of diarrhea among vulnerable children worldwide. With the evidence presented here, we highlight the need for future research as well as the potential for astrovirus to be a target for vaccine development." @default.
• W2777309499 created "2018-01-05" @default.
• W2777309499 creator A5006872102 @default.
• W2777309499 creator A5007061685 @default.
• W2777309499 creator A5008790762 @default.
• W2777309499 creator A5011924977 @default.
• W2777309499 creator A5024319683 @default.
• W2777309499 creator A5024473138 @default.
• W2777309499 creator A5025928805 @default.
• W2777309499 creator A5036391921 @default.
• W2777309499 creator A5037272111 @default.
• W2777309499 creator A5039433364 @default.
• W2777309499 creator A5042853615 @default.
• W2777309499 creator A5043728694 @default.
• W2777309499 creator A5051239535 @default.
• W2777309499 creator A5051818098 @default.
• W2777309499 creator A5065477615 @default.
• W2777309499 creator A5067727182 @default.
• W2777309499 creator A5069940679 @default.
• W2777309499 creator A5071816628 @default.
• W2777309499 creator A5073387169 @default.
• W2777309499 creator A5081116359 @default.
• W2777309499 creator A5082667457 @default.
• W2777309499 creator A5083229062 @default.
• W2777309499 creator A5083759768 @default.
• W2777309499 creator A5084152395 @default.
• W2777309499 creator A5084419236 @default.
• W2777309499 creator A5085793844 @default.
• W2777309499 creator A5087299636 @default.
• W2777309499 creator A5089512708 @default.
• W2777309499 date "2018-01-01" @default.
• W2777309499 modified "2023-10-14" @default.
• W2777309499 title "Astrovirus Infection and Diarrhea in 8 Countries" @default.
• W2777309499 cites W1761674311 @default.
• W2777309499 cites W1762084525 @default.
• W2777309499 cites W1821981622 @default.
• W2777309499 cites W1924064069 @default.
• W2777309499 cites W1965614634 @default.
• W2777309499 cites W1975574641 @default.
• W2777309499 cites W1983691330 @default.
• W2777309499 cites W1985969657 @default.
• W2777309499 cites W1997170466 @default.
• W2777309499 cites W2004015988 @default.
• W2777309499 cites W2012807335 @default.
• W2777309499 cites W2026035366 @default.
• W2777309499 cites W2029361479 @default.
• W2777309499 cites W2040935632 @default.
• W2777309499 cites W2041703943 @default.
• W2777309499 cites W2061702680 @default.
• W2777309499 cites W2074029700 @default.
• W2777309499 cites W2078497184 @default.
• W2777309499 cites W2090737457 @default.
• W2777309499 cites W2118198749 @default.
• W2777309499 cites W2145147225 @default.
• W2777309499 cites W2145373855 @default.
• W2777309499 cites W2150069228 @default.
• W2777309499 cites W2150243094 @default.
• W2777309499 cites W2159638395 @default.
• W2777309499 cites W2164367095 @default.
• W2777309499 cites W2166093730 @default.
• W2777309499 cites W2167470545 @default.
• W2777309499 cites W2311466146 @default.
• W2777309499 cites W2316938431 @default.
• W2777309499 cites W2331560135 @default.
• W2777309499 cites W2341508685 @default.
• W2777309499 cites W2395038787 @default.
• W2777309499 cites W2463372205 @default.
• W2777309499 cites W2468071545 @default.
• W2777309499 cites W4211204104 @default.
• W2777309499 cites W4254400776 @default.
• W2777309499 doi "https://doi.org/10.1542/peds.2017-1326" @default.
• W2777309499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29259078" @default.
• W2777309499 hasPublicationYear "2018" @default.
• W2777309499 type Work @default.
• W2777309499 sameAs 2777309499 @default.
• W2777309499 citedByCount "47" @default.
• W2777309499 countsByYear W27773094992018 @default.
• W2777309499 countsByYear W27773094992019 @default.
• W2777309499 countsByYear W27773094992020 @default.
• W2777309499 countsByYear W27773094992021 @default.
• W2777309499 countsByYear W27773094992022 @default.
• W2777309499 countsByYear W27773094992023 @default.
• W2777309499 crossrefType "journal-article" @default.
• W2777309499 hasAuthorship W2777309499A5006872102 @default.
• W2777309499 hasAuthorship W2777309499A5007061685 @default.
• W2777309499 hasAuthorship W2777309499A5008790762 @default.
• W2777309499 hasAuthorship W2777309499A5011924977 @default.
• W2777309499 hasAuthorship W2777309499A5024319683 @default.
• W2777309499 hasAuthorship W2777309499A5024473138 @default.
• W2777309499 hasAuthorship W2777309499A5025928805 @default.
• W2777309499 hasAuthorship W2777309499A5036391921 @default.
• W2777309499 hasAuthorship W2777309499A5037272111 @default.
• W2777309499 hasAuthorship W2777309499A5039433364 @default.
• W2777309499 hasAuthorship W2777309499A5042853615 @default.
• W2777309499 hasAuthorship W2777309499A5043728694 @default.
• W2777309499 hasAuthorship W2777309499A5051239535 @default.
• W2777309499 hasAuthorship W2777309499A5051818098 @default.
• W2777309499 hasAuthorship W2777309499A5065477615 @default.
• W2777309499 hasAuthorship W2777309499A5067727182 @default.
• W2777309499 hasAuthorship W2777309499A5069940679 @default.

• next