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- W2777883862 abstract "To compare levels of HbA2, HbE, HbF, and red cell parameters (total Hb, PCV, MCV, and MCH) and also determine their appropriated cut-off points for initial discrimination between homozygous HbE with and without α0-thalassemia trait. Hb analysis results from capillary electrophoresis (CE) and red cell parameters of homozygous HbE without α0-thalassemia trait (n = 41) and with α0-thalassemia trait (n = 17) were reviewed. The MCV, MCH, and HbE of homozygous HbE with α0-thalassemia trait were significantly lower than those of homozygous HbE without α0-thalassemia, while HbA2 levels of the former were significantly higher than those of the latter. HbA2 at a cut-off point of 5.3% had 69.0% efficiency in discrimination between the 2 groups. It could also reduce 56.1% of homozygous HbE samples for α0-thalassemia testing. The elevated HbA2 ≥5.3% is a useful marker for initial discrimination between homozygous HbE with and without α0-thalassemia trait." @default.
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- W2777883862 date "2017-12-18" @default.
- W2777883862 modified "2023-09-23" @default.
- W2777883862 title "Comparison of HbA2, E, F and Red Cell Parameters in Homozygous HbE With and Without α0-Thalassemia Trait" @default.
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- W2777883862 doi "https://doi.org/10.1093/labmed/lmx083" @default.
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