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- W2777915237 abstract "Tendons adapt to load under normal physiological conditions, however, under extreme loading conditions, such as those experienced by elite endurance athletes, incomplete adaptation may occur and cause injury. The prevalence of tendinopathies in elite endurance athletes is approximately 50%, thus variability exists in an athlete’s tolerance to extreme loading. A number of intrinsic and extrinsic factors contribute to modulating injury risk, some of which are modifiable and others, such as genetic variants, are non-modifiable. It was hypothesised that elite marathon runners would possess a genotype associated with enhanced tendon function, and thus protective against tendinopathy. Here, we compared the genotype frequencies of six genetic variants (COL1A1 rs1800012, VEGFA rs699947, TIMP2 rs4789932, MMP3 rs591058, MMP3 rs650108, MMP3 rs679620), previously associated with tendinopathy, in elite (men" @default.
- W2777915237 created "2018-01-05" @default.
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- W2777915237 date "2017-12-01" @default.
- W2777915237 modified "2023-09-25" @default.
- W2777915237 title "18 No association between tendon-related genes and performance in elite european caucasian marathon runners" @default.
- W2777915237 doi "https://doi.org/10.1136/bjsports-2017-098966.22" @default.
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