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- W2777951837 abstract "Background: Because of clinical similarities, pulmonary embolism (PE) suspicion may be difficult in COPD outpatients admitted for acute exacerbation (COPD-E), and PE may occur in inpatients hospitalized for COPD-E. Observational studies founded a wide range of PE prevalence during COPD-E. As PE prevalence may vary according to patients’ setting, we assessed PE prevalence in patients with COPD-E according to their status (outpatients vs inpatients). Methods: We performed a meta-analysis of observational prospective studies investigating PE prevalence in patients admitted for COPD-E. Included studies were only those with systematic PE assessment in patients admitted for COPD-E as the primary aim. The primary endpoint was prevalence of objectively confirmed PE, weighted by the size of the study, and thereafter according to patients’ setting. A sensitivity analysis was performed in the following subcategories: definition of COPD using spirometry, definition of COPD-E. Results: Fourteen studies (2016 patients) were included. The overall PE prevalence was 17% (95%CI [11-23], random effects model). PE prevalence (figure 1) was lower for outpatients (9% [2-19]) than inpatients (20% [11-31]), p for interaction=0.12. The prevalence was not influenced by definition of COPD using spirometry or definition of COPD-E. Conclusion: Our meta-analysis highlights that the PE prevalence varies according to patients’ setting doubling from emergency department to medical ward." @default.
- W2777951837 created "2018-01-05" @default.
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- W2777951837 date "2017-09-01" @default.
- W2777951837 modified "2023-10-04" @default.
- W2777951837 title "Impact of patients’ setting on the prevalence of pulmonary embolism in acute exacerbation of COPD: a meta-analysis of observational studies" @default.
- W2777951837 doi "https://doi.org/10.1183/1393003.congress-2017.pa2350" @default.
- W2777951837 hasPublicationYear "2017" @default.
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